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Page 1
Integrative genomic analyses of neurofibromatosis tumours identify SOX9 as a biomarker and survival gene.
Miller SJ, Jessen WJ, Mehta T, Hardiman A, Sites E, Kaiser S, Jegga AG, Li H, Upadhyaya M, Giovannini M, Muir D, Wallace MR, Lopez E, Serra E, Nielsen GP, Lazaro C, Stemmer-Rachamimov A, Page G, Aronow BJ, Ratner N. Miller SJ, et al. Among authors: jessen wj. EMBO Mol Med. 2009 Jul;1(4):236-48. doi: 10.1002/emmm.200900027. EMBO Mol Med. 2009. PMID: 20049725 Free PMC article.
Ras-driven transcriptome analysis identifies aurora kinase A as a potential malignant peripheral nerve sheath tumor therapeutic target.
Patel AV, Eaves D, Jessen WJ, Rizvi TA, Ecsedy JA, Qian MG, Aronow BJ, Perentesis JP, Serra E, Cripe TP, Miller SJ, Ratner N. Patel AV, et al. Among authors: jessen wj. Clin Cancer Res. 2012 Sep 15;18(18):5020-30. doi: 10.1158/1078-0432.CCR-12-1072. Epub 2012 Jul 18. Clin Cancer Res. 2012. PMID: 22811580 Free PMC article.
MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors.
Jessen WJ, Miller SJ, Jousma E, Wu J, Rizvi TA, Brundage ME, Eaves D, Widemann B, Kim MO, Dombi E, Sabo J, Hardiman Dudley A, Niwa-Kawakita M, Page GP, Giovannini M, Aronow BJ, Cripe TP, Ratner N. Jessen WJ, et al. J Clin Invest. 2013 Jan;123(1):340-7. doi: 10.1172/JCI60578. Epub 2012 Dec 10. J Clin Invest. 2013. PMID: 23221341 Free PMC article. Clinical Trial.
The SWI/SNF ATPase Brm is a gatekeeper of proliferative control in prostate cancer.
Shen H, Powers N, Saini N, Comstock CE, Sharma A, Weaver K, Revelo MP, Gerald W, Williams E, Jessen WJ, Aronow BJ, Rosson G, Weissman B, Muchardt C, Yaniv M, Knudsen KE. Shen H, et al. Among authors: jessen wj. Cancer Res. 2008 Dec 15;68(24):10154-62. doi: 10.1158/0008-5472.CAN-08-1794. Cancer Res. 2008. PMID: 19074882 Free PMC article.
PTEN and NF1 inactivation in Schwann cells produces a severe phenotype in the peripheral nervous system that promotes the development and malignant progression of peripheral nerve sheath tumors.
Keng VW, Rahrmann EP, Watson AL, Tschida BR, Moertel CL, Jessen WJ, Rizvi TA, Collins MH, Ratner N, Largaespada DA. Keng VW, et al. Among authors: jessen wj. Cancer Res. 2012 Jul 1;72(13):3405-13. doi: 10.1158/0008-5472.CAN-11-4092. Epub 2012 Jun 14. Cancer Res. 2012. PMID: 22700876 Free PMC article.
Insertional Mutagenesis Identifies a STAT3/Arid1b/β-catenin Pathway Driving Neurofibroma Initiation.
Wu J, Keng VW, Patmore DM, Kendall JJ, Patel AV, Jousma E, Jessen WJ, Choi K, Tschida BR, Silverstein KA, Fan D, Schwartz EB, Fuchs JR, Zou Y, Kim MO, Dombi E, Levy DE, Huang G, Cancelas JA, Stemmer-Rachamimov AO, Spinner RJ, Largaespada DA, Ratner N. Wu J, et al. Among authors: jessen wj. Cell Rep. 2016 Mar 1;14(8):1979-90. doi: 10.1016/j.celrep.2016.01.074. Epub 2016 Feb 18. Cell Rep. 2016. PMID: 26904939 Free PMC article.
Cxcr3-expressing leukocytes are necessary for neurofibroma formation in mice.
Fletcher JS, Wu J, Jessen WJ, Pundavela J, Miller JA, Dombi E, Kim MO, Rizvi TA, Chetal K, Salomonis N, Ratner N. Fletcher JS, et al. Among authors: jessen wj. JCI Insight. 2019 Feb 7;4(3):e98601. doi: 10.1172/jci.insight.98601. JCI Insight. 2019. PMID: 30728335 Free PMC article.
26 results