Saravanan M - Search Results

1

Generation of a manganese specific restriction endonuclease with nicking activity.

Vasu K, Saravanan M, Rajendra BV, Nagaraja V. Vasu K, et al. Among authors: saravanan m. Biochemistry. 2010 Sep 28;49(38):8425-33. doi: 10.1021/bi101035k. Biochemistry. 2010. PMID: 20734974

2

Ca(2+)-mediated site-specific DNA cleavage and suppression of promiscuous activity of KpnI restriction endonuclease.

Chandrashekaran S, Saravanan M, Radha DR, Nagaraja V. Chandrashekaran S, et al. Among authors: saravanan m. J Biol Chem. 2004 Nov 26;279(48):49736-40. doi: 10.1074/jbc.M409483200. Epub 2004 Sep 16. J Biol Chem. 2004. PMID: 15375161 Free article.

3

Type II restriction endonuclease R.KpnI is a member of the HNH nuclease superfamily.

Saravanan M, Bujnicki JM, Cymerman IA, Rao DN, Nagaraja V. Saravanan M, et al. Nucleic Acids Res. 2004 Nov 23;32(20):6129-35. doi: 10.1093/nar/gkh951. Print 2004. Nucleic Acids Res. 2004. PMID: 15562004 Free PMC article.

4

R.KpnI, an HNH superfamily REase, exhibits differential discrimination at non-canonical sequences in the presence of Ca2+ and Mg2+.

Saravanan M, Vasu K, Kanakaraj R, Rao DN, Nagaraja V. Saravanan M, et al. Nucleic Acids Res. 2007;35(8):2777-86. doi: 10.1093/nar/gkm114. Epub 2007 Apr 11. Nucleic Acids Res. 2007. PMID: 17430971 Free PMC article.

5

Dual role for Zn2+ in maintaining structural integrity and inducing DNA sequence specificity in a promiscuous endonuclease.

Saravanan M, Vasu K, Ghosh S, Nagaraja V. Saravanan M, et al. J Biol Chem. 2007 Nov 2;282(44):32320-6. doi: 10.1074/jbc.M705927200. Epub 2007 Sep 4. J Biol Chem. 2007. PMID: 17785455 Free article.

6

Structural integrity of the beta beta alpha-Metal finger motif is required for DNA binding and stable protein-DNA complex formation in R.KpnI.

Vasu K, Saravanan M, Bujnicki JM, Nagaraja V. Vasu K, et al. Among authors: saravanan m. Biochim Biophys Acta. 2008 Feb;1784(2):269-75. doi: 10.1016/j.bbapap.2007.07.011. Biochim Biophys Acta. 2008. PMID: 18329982

7

Evolution of sequence specificity in a restriction endonuclease by a point mutation.

Saravanan M, Vasu K, Nagaraja V. Saravanan M, et al. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10344-7. doi: 10.1073/pnas.0804974105. Epub 2008 Jul 22. Proc Natl Acad Sci U S A. 2008. PMID: 18647833 Free PMC article.

8

Endonuclease active site plasticity allows DNA cleavage with diverse alkaline Earth and transition metal ions.

Vasu K, Saravanan M, Nagaraja V. Vasu K, et al. Among authors: saravanan m. ACS Chem Biol. 2011 Sep 16;6(9):934-42. doi: 10.1021/cb200107y. Epub 2011 Jul 7. ACS Chem Biol. 2011. PMID: 21736285

9

Functional expression and purification of Anabaena PCC 7120 XisA protein.

Trivedi U, Kaushik S, Kunjadia P, Saravanan M, Nagaraja V, Archana G, Nareshkumar G. Trivedi U, et al. Among authors: saravanan m. Protein Expr Purif. 2016 Feb;118:64-9. doi: 10.1016/j.pep.2015.09.027. Epub 2015 Oct 3. Protein Expr Purif. 2016. PMID: 26434536

10

Interactions between the nucleosome histone core and Arp8 in the INO80 chromatin remodeling complex.

Saravanan M, Wuerges J, Bose D, McCormack EA, Cook NJ, Zhang X, Wigley DB. Saravanan M, et al. Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):20883-8. doi: 10.1073/pnas.1214735109. Epub 2012 Dec 3. Proc Natl Acad Sci U S A. 2012. PMID: 23213201 Free PMC article.

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