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Phase I/II clinical study of Tosedostat, an inhibitor of aminopeptidases, in patients with acute myeloid leukemia and myelodysplasia.
Löwenberg B, Morgan G, Ossenkoppele GJ, Burnett AK, Zachée P, Dührsen U, Dierickx D, Müller-Tidow C, Sonneveld P, Krug U, Bone E, Flores N, Richardson AF, Hooftman L, Jenkins C, Zweegman S, Davies F. Löwenberg B, et al. Among authors: burnett ak. J Clin Oncol. 2010 Oct 1;28(28):4333-8. doi: 10.1200/JCO.2009.27.6295. Epub 2010 Aug 23. J Clin Oncol. 2010. PMID: 20733120 Clinical Trial.
Acute myeloid leukemia.
Löwenberg B, Downing JR, Burnett A. Löwenberg B, et al. N Engl J Med. 1999 Sep 30;341(14):1051-62. doi: 10.1056/NEJM199909303411407. N Engl J Med. 1999. PMID: 10502596 Review. No abstract available.
Dose-finding study of valspodar (PSC 833) with daunorubicin and cytarabine to reverse multidrug resistance in elderly patients with previously untreated acute myeloid leukemia.
Sonneveld P, Burnett A, Vossebeld P, Ben-Am M, Rosenkranz G, Pfister C, Verhoef G, Dekker A, Ossenkoppele G, Ferrant C, Yin L, Gratwohl A, Kovacsovics T, Vellenga E, Capdeville R, Löwenberg B. Sonneveld P, et al. Hematol J. 2000;1(6):411-21. doi: 10.1038/sj.thj.6200050. Hematol J. 2000. PMID: 11920222 Clinical Trial.
The value of the MDR1 reversal agent PSC-833 in addition to daunorubicin and cytarabine in the treatment of elderly patients with previously untreated acute myeloid leukemia (AML), in relation to MDR1 status at diagnosis.
van der Holt B, Löwenberg B, Burnett AK, Knauf WU, Shepherd J, Piccaluga PP, Ossenkoppele GJ, Verhoef GE, Ferrant A, Crump M, Selleslag D, Theobald M, Fey MF, Vellenga E, Dugan M, Sonneveld P. van der Holt B, et al. Among authors: burnett ak. Blood. 2005 Oct 15;106(8):2646-54. doi: 10.1182/blood-2005-04-1395. Epub 2005 Jun 30. Blood. 2005. PMID: 15994288 Free article. Clinical Trial.
Various distinctive cytogenetic abnormalities in patients with acute myeloid leukaemia aged 60 years and older express adverse prognostic value: results from a prospective clinical trial.
van der Holt B, Breems DA, Berna Beverloo H, van den Berg E, Burnett AK, Sonneveld P, Löwenberg B. van der Holt B, et al. Among authors: burnett ak. Br J Haematol. 2007 Jan;136(1):96-105. doi: 10.1111/j.1365-2141.2006.06403.x. Epub 2006 Nov 24. Br J Haematol. 2007. PMID: 17129222 Free article.
CD34-related coexpression of MDR1 and BCRP indicates a clinically resistant phenotype in patients with acute myeloid leukemia (AML) of older age.
van den Heuvel-Eibrink MM, van der Holt B, Burnett AK, Knauf WU, Fey MF, Verhoef GE, Vellenga E, Ossenkoppele GJ, Löwenberg B, Sonneveld P. van den Heuvel-Eibrink MM, et al. Among authors: burnett ak. Ann Hematol. 2007 May;86(5):329-37. doi: 10.1007/s00277-007-0269-7. Epub 2007 Mar 6. Ann Hematol. 2007. PMID: 17340137 Free PMC article. Clinical Trial.
Mutation of the Wilms' tumor 1 gene is a poor prognostic factor associated with chemotherapy resistance in normal karyotype acute myeloid leukemia: the United Kingdom Medical Research Council Adult Leukaemia Working Party.
Virappane P, Gale R, Hills R, Kakkas I, Summers K, Stevens J, Allen C, Green C, Quentmeier H, Drexler H, Burnett A, Linch D, Bonnet D, Lister TA, Fitzgibbon J. Virappane P, et al. J Clin Oncol. 2008 Nov 20;26(33):5429-35. doi: 10.1200/JCO.2008.16.0333. Epub 2008 Jun 30. J Clin Oncol. 2008. PMID: 18591546
310 results