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Genistein-mediated inhibition of glycosaminoglycan synthesis, which corrects storage in cells of patients suffering from mucopolysaccharidoses, acts by influencing an epidermal growth factor-dependent pathway.
Jakóbkiewicz-Banecka J, Piotrowska E, Narajczyk M, Barańska S, Wegrzyn G. Jakóbkiewicz-Banecka J, et al. Among authors: piotrowska e. J Biomed Sci. 2009 Mar 2;16(1):26. doi: 10.1186/1423-0127-16-26. J Biomed Sci. 2009. PMID: 19272193 Free PMC article.
Genistein: a natural isoflavone with a potential for treatment of genetic diseases.
Wegrzyn G, Jakóbkiewicz-Banecka J, Gabig-Cimińska M, Piotrowska E, Narajczyk M, Kloska A, Malinowska M, Dziedzic D, Gołebiewska I, Moskot M, Wegrzyn A. Wegrzyn G, et al. Among authors: piotrowska e. Biochem Soc Trans. 2010 Apr;38(2):695-701. doi: 10.1042/BST0380695. Biochem Soc Trans. 2010. PMID: 20298245 Review.
Two-year follow-up of Sanfilippo Disease patients treated with a genistein-rich isoflavone extract: assessment of effects on cognitive functions and general status of patients.
Piotrowska E, Jakobkiewicz-Banecka J, Maryniak A, Tylki-Szymanska A, Puk E, Liberek A, Wegrzyn A, Czartoryska B, Slominska-Wojewodzka M, Wegrzyn G. Piotrowska E, et al. Med Sci Monit. 2011 Apr;17(4):CR196-202. doi: 10.12659/msm.881715. Med Sci Monit. 2011. PMID: 21455105 Free PMC article. Clinical Trial.
87 results