House L - Search Results

1

A pharmacogenetic study of vorinostat glucuronidation.

Kang SP, Ramirez J, House L, Zhang W, Mirkov S, Liu W, Haverfield E, Ratain MJ. Kang SP, et al. Among authors: house l. Pharmacogenet Genomics. 2010 Oct;20(10):638-41. doi: 10.1097/FPC.0b013e32833e1b37. Pharmacogenet Genomics. 2010. PMID: 20729791 Free PMC article.

2

Glucuronidation of OTS167 in Humans Is Catalyzed by UDP-Glucuronosyltransferases UGT1A1, UGT1A3, UGT1A8, and UGT1A10.

Ramírez J, Mirkov S, House LK, Ratain MJ. Ramírez J, et al. Drug Metab Dispos. 2015 Jul;43(7):928-35. doi: 10.1124/dmd.115.063271. Epub 2015 Apr 13. Drug Metab Dispos. 2015. PMID: 25870101 Free PMC article.

3

The UGT1A1*28 polymorphism correlates with erlotinib's effect on SN-38 glucuronidation.

Liu Y, Ramírez J, House L, Ratain MJ. Liu Y, et al. Among authors: house l. Eur J Cancer. 2010 Jul;46(11):2097-103. doi: 10.1016/j.ejca.2010.04.022. Epub 2010 May 23. Eur J Cancer. 2010. PMID: 20580994 Free PMC article.

4

Comparison of the drug-drug interactions potential of erlotinib and gefitinib via inhibition of UDP-glucuronosyltransferases.

Liu Y, Ramírez J, House L, Ratain MJ. Liu Y, et al. Among authors: house l. Drug Metab Dispos. 2010 Jan;38(1):32-9. doi: 10.1124/dmd.109.029660. Drug Metab Dispos. 2010. PMID: 19850672 Free PMC article.

5

Evaluation of utility of pharmacokinetic studies in phase I trials of two oncology drugs.

Wu K, House L, Ramírez J, Seminerio MJ, Ratain MJ. Wu K, et al. Among authors: house l. Clin Cancer Res. 2013 Nov 1;19(21):6039-43. doi: 10.1158/1078-0432.CCR-13-0597. Epub 2013 Sep 20. Clin Cancer Res. 2013. PMID: 24056785 Free PMC article.

6

In vitro glucuronidation of aprepitant: a moderate inhibitor of UGT2B7.

House L, Ramirez J, Seminerio M, Mirkov S, Ratain MJ. House L, et al. Xenobiotica. 2015;45(11):990-8. doi: 10.3109/00498254.2015.1038743. Epub 2015 Jun 8. Xenobiotica. 2015. PMID: 26053558 Free PMC article.

7

Metabolism of megestrol acetate in vitro and the role of oxidative metabolites.

House L, Seminerio MJ, Mirkov S, Ramirez J, Skor M, Sachleben JR, Isikbay M, Singhal H, Greene GL, Vander Griend D, Conzen SD, Ratain MJ. House L, et al. Xenobiotica. 2018 Oct;48(10):973-983. doi: 10.1080/00498254.2017.1386335. Epub 2017 Nov 10. Xenobiotica. 2018. PMID: 29050522 Free PMC article.

8

Influence of N-acetyltransferase 2 gene polymorphisms on the in vitro metabolism of the epidermal growth factor receptor inhibitor rociletinib.

Ramirez J, House LK, Ratain MJ. Ramirez J, et al. Br J Clin Pharmacol. 2021 Nov;87(11):4313-4322. doi: 10.1111/bcp.14848. Epub 2021 Apr 27. Br J Clin Pharmacol. 2021. PMID: 33818816 Free article.

9

Dose-finding and pharmacokinetic study to optimize the dosing of irinotecan according to the UGT1A1 genotype of patients with cancer.

Innocenti F, Schilsky RL, Ramírez J, Janisch L, Undevia S, House LK, Das S, Wu K, Turcich M, Marsh R, Karrison T, Maitland ML, Salgia R, Ratain MJ. Innocenti F, et al. Among authors: house lk. J Clin Oncol. 2014 Aug 1;32(22):2328-34. doi: 10.1200/JCO.2014.55.2307. Epub 2014 Jun 23. J Clin Oncol. 2014. PMID: 24958824 Free PMC article. Clinical Trial.

10

A phase I and pharmacokinetic study of the quinoxaline antitumour Agent R(+)XK469 in patients with advanced solid tumours.

Undevia SD, Innocenti F, Ramirez J, House L, Desai AA, Skoog LA, Singh DA, Karrison T, Kindler HL, Ratain MJ. Undevia SD, et al. Among authors: house l. Eur J Cancer. 2008 Aug;44(12):1684-92. doi: 10.1016/j.ejca.2008.05.018. Epub 2008 Jul 21. Eur J Cancer. 2008. PMID: 18650079 Free PMC article. Clinical Trial.

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