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Discovery and Preclinical Characterization of Fulacimstat (BAY 1142524), a Potent and Selective Chymase Inhibitor As a New Profibrinolytic Approach for Safe Thrombus Resolution.
Fürstner C, Ackerstaff J, Meier H, Straub A, Mittendorf J, Schamberger J, Schäfer M, Börngen K, Jörißen H, Zubov D, Zimmermann K, Tersteegen A, Geiss V, Hartmann E, Albrecht-Küpper B, D'Orléans-Juste P, Lapointe C, Vincent L, Heitmeier S, Tinel H. Fürstner C, et al. Among authors: meier h. J Med Chem. 2024 Nov 14. doi: 10.1021/acs.jmedchem.4c01819. Online ahead of print. J Med Chem. 2024. PMID: 39541507
Naphthol derivatives as TRPV1 inhibitors for the treatment of urinary incontinence.
Urbahns K, Yura T, Mogi M, Tajimi M, Fujishima H, Masuda T, Yoshida N, Moriwaki T, Lowinger TB, Meier H, Chan F, Madge D, Gupta JB. Urbahns K, et al. Among authors: meier h. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3354-7. doi: 10.1016/j.bmcl.2011.04.013. Epub 2011 Apr 9. Bioorg Med Chem Lett. 2011. PMID: 21531136
A lower X-gate in TASK channels traps inhibitors within the vestibule.
Rödström KEJ, Kiper AK, Zhang W, Rinné S, Pike ACW, Goldstein M, Conrad LJ, Delbeck M, Hahn MG, Meier H, Platzk M, Quigley A, Speedman D, Shrestha L, Mukhopadhyay SMM, Burgess-Brown NA, Tucker SJ, Müller T, Decher N, Carpenter EP. Rödström KEJ, et al. Among authors: meier h. Nature. 2020 Jun;582(7812):443-447. doi: 10.1038/s41586-020-2250-8. Epub 2020 Apr 29. Nature. 2020. PMID: 32499642
Historical redlining and clustering of present-day breast cancer factors.
Lima SM, Palermo TM, Aldstadt J, Tian L, Meier HCS, Louis HT Jr, Ochs-Balcom HM. Lima SM, et al. Among authors: meier hcs. Cancer Causes Control. 2025 Jan 4. doi: 10.1007/s10552-024-01950-9. Online ahead of print. Cancer Causes Control. 2025. PMID: 39755825
513 results