Kay MA - Search Results

1

Hyperactive sleeping beauty transposase enables persistent phenotypic correction in mice and a canine model for hemophilia B.

Hausl MA, Zhang W, Müther N, Rauschhuber C, Franck HG, Merricks EP, Nichols TC, Kay MA, Ehrhardt A. Hausl MA, et al. Among authors: kay ma. Mol Ther. 2010 Nov;18(11):1896-906. doi: 10.1038/mt.2010.169. Epub 2010 Aug 17. Mol Ther. 2010. PMID: 20717103 Free PMC article.

2

A direct comparison of two nonviral gene therapy vectors for somatic integration: in vivo evaluation of the bacteriophage integrase phiC31 and the Sleeping Beauty transposase.

Ehrhardt A, Xu H, Huang Z, Engler JA, Kay MA. Ehrhardt A, et al. Among authors: kay ma. Mol Ther. 2005 May;11(5):695-706. doi: 10.1016/j.ymthe.2005.01.010. Mol Ther. 2005. PMID: 15851008 Free article.

3

A rapid protocol for construction and production of high-capacity adenoviral vectors.

Jager L, Hausl MA, Rauschhuber C, Wolf NM, Kay MA, Ehrhardt A. Jager L, et al. Among authors: kay ma. Nat Protoc. 2009;4(4):547-64. doi: 10.1038/nprot.2009.4. Nat Protoc. 2009. PMID: 19373227

4

A gene-deleted adenoviral vector results in phenotypic correction of canine hemophilia B without liver toxicity or thrombocytopenia.

Ehrhardt A, Xu H, Dillow AM, Bellinger DA, Nichols TC, Kay MA. Ehrhardt A, et al. Among authors: kay ma. Blood. 2003 Oct 1;102(7):2403-11. doi: 10.1182/blood-2003-01-0314. Epub 2003 Jun 12. Blood. 2003. PMID: 12805062 Free article.

5

Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo.

Chen ZY, He CY, Ehrhardt A, Kay MA. Chen ZY, et al. Among authors: kay ma. Mol Ther. 2003 Sep;8(3):495-500. doi: 10.1016/s1525-0016(03)00168-0. Mol Ther. 2003. PMID: 12946323 Free article.

6

Somatic integration from an adenoviral hybrid vector into a hot spot in mouse liver results in persistent transgene expression levels in vivo.

Ehrhardt A, Yant SR, Giering JC, Xu H, Engler JA, Kay MA. Ehrhardt A, et al. Among authors: kay ma. Mol Ther. 2007 Jan;15(1):146-56. doi: 10.1038/sj.mt.6300011. Mol Ther. 2007. PMID: 17164786 Free article.

7

Adenovirus transduction is required for the correction of diabetes using Pdx-1 or Neurogenin-3 in the liver.

Wang AY, Ehrhardt A, Xu H, Kay MA. Wang AY, et al. Among authors: kay ma. Mol Ther. 2007 Feb;15(2):255-63. doi: 10.1038/sj.mt.6300032. Mol Ther. 2007. PMID: 17235302 Free article.

8

Translational data from adeno-associated virus-mediated gene therapy of hemophilia B in dogs.

Nichols TC, Whitford MH, Arruda VR, Stedman HH, Kay MA, High KA. Nichols TC, et al. Among authors: kay ma. Hum Gene Ther Clin Dev. 2015 Mar;26(1):5-14. doi: 10.1089/humc.2014.153. Epub 2015 Feb 12. Hum Gene Ther Clin Dev. 2015. PMID: 25675273 Free PMC article. Review.

9

Optimization of cis-acting elements for gene expression from nonviral vectors in vivo.

Ehrhardt A, Peng PD, Xu H, Meuse L, Kay MA. Ehrhardt A, et al. Among authors: kay ma. Hum Gene Ther. 2003 Feb 10;14(3):215-25. doi: 10.1089/10430340360535779. Hum Gene Ther. 2003. PMID: 12639302

10

The host response to adenovirus, helper-dependent adenovirus, and adeno-associated virus in mouse liver.

McCaffrey AP, Fawcett P, Nakai H, McCaffrey RL, Ehrhardt A, Pham TT, Pandey K, Xu H, Feuss S, Storm TA, Kay MA. McCaffrey AP, et al. Among authors: kay ma. Mol Ther. 2008 May;16(5):931-41. doi: 10.1038/mt.2008.37. Epub 2008 Mar 18. Mol Ther. 2008. PMID: 18388926 Free article.

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