Gutterman JU - Search Results

1

Natural triterpenoid avicins selectively induce tumor cell death.

Wang H, Haridas V, Gutterman JU, Xu ZX. Wang H, et al. Among authors: gutterman ju. Commun Integr Biol. 2010 May;3(3):205-8. doi: 10.4161/cib.3.3.11492. Commun Integr Biol. 2010. PMID: 20714394 Free PMC article.

2

Avicin D, a plant triterpenoid, induces cell apoptosis by recruitment of Fas and downstream signaling molecules into lipid rafts.

Xu ZX, Ding T, Haridas V, Connolly F, Gutterman JU. Xu ZX, et al. Among authors: gutterman ju. PLoS One. 2009 Dec 31;4(12):e8532. doi: 10.1371/journal.pone.0008532. PLoS One. 2009. PMID: 20046832 Free PMC article.

3

Triterpenoid electrophiles (avicins) suppress heat shock protein-70 and x-linked inhibitor of apoptosis proteins in malignant cells by activation of ubiquitin machinery: implications for proapoptotic activity.

Gaikwad A, Poblenz A, Haridas V, Zhang C, Duvic M, Gutterman J. Gaikwad A, et al. Clin Cancer Res. 2005 Mar 1;11(5):1953-62. doi: 10.1158/1078-0432.CCR-04-1704. Clin Cancer Res. 2005. PMID: 15756021

4

Avicins, natural anticancer saponins, permeabilize mitochondrial membranes.

Lemeshko VV, Haridas V, Quijano Pérez JC, Gutterman JU. Lemeshko VV, et al. Among authors: gutterman ju. Arch Biochem Biophys. 2006 Oct 15;454(2):114-22. doi: 10.1016/j.abb.2006.08.008. Epub 2006 Aug 23. Arch Biochem Biophys. 2006. PMID: 16962987

5

Avicins, a novel plant-derived metabolite lowers energy metabolism in tumor cells by targeting the outer mitochondrial membrane.

Haridas V, Li X, Mizumachi T, Higuchi M, Lemeshko VV, Colombini M, Gutterman JU. Haridas V, et al. Among authors: gutterman ju. Mitochondrion. 2007 May;7(3):234-40. doi: 10.1016/j.mito.2006.12.005. Epub 2007 Jan 12. Mitochondrion. 2007. PMID: 17317337

6

Avicins, a family of triterpenoid saponins from Acacia victoriae (Bentham), inhibit activation of nuclear factor-kappaB by inhibiting both its nuclear localization and ability to bind DNA.

Haridas V, Arntzen CJ, Gutterman JU. Haridas V, et al. Among authors: gutterman ju. Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11557-62. doi: 10.1073/pnas.191363498. Proc Natl Acad Sci U S A. 2001. PMID: 11572998 Free PMC article.

7

Avicins: triterpenoid saponins from Acacia victoriae (Bentham) induce apoptosis by mitochondrial perturbation.

Haridas V, Higuchi M, Jayatilake GS, Bailey D, Mujoo K, Blake ME, Arntzen CJ, Gutterman JU. Haridas V, et al. Among authors: gutterman ju. Proc Natl Acad Sci U S A. 2001 May 8;98(10):5821-6. doi: 10.1073/pnas.101619098. Proc Natl Acad Sci U S A. 2001. PMID: 11344312 Free PMC article.

8

Metabolomics of plant saponins: bioprospecting triterpene glycoside diversity with respect to mammalian cell targets.

Joshi L, Van Eck JM, Mayo K, Di Silvestro R, Blake Nieto ME, Ganapathi T, Haridas V, Gutterman JU, Arntzen CJ. Joshi L, et al. Among authors: gutterman ju. OMICS. 2002;6(3):235-46. doi: 10.1089/15362310260256891. OMICS. 2002. PMID: 12427275

9

Isolation and structures of avicins D and G: in vitro tumor-inhibitory saponins derived from Acacia victoriae.

Jayatilake GS, Freeberg DR, Liu Z, Richheimer SL, Blake Nieto ME, Bailey DT, Haridas V, Gutterman JU. Jayatilake GS, et al. Among authors: gutterman ju. J Nat Prod. 2003 Jun;66(6):779-83. doi: 10.1021/np020400v. J Nat Prod. 2003. PMID: 12828461

10

Triterpenoid electrophiles (avicins) activate the innate stress response by redox regulation of a gene battery.

Haridas V, Hanausek M, Nishimura G, Soehnge H, Gaikwad A, Narog M, Spears E, Zoltaszek R, Walaszek Z, Gutterman JU. Haridas V, et al. Among authors: gutterman ju. J Clin Invest. 2004 Jan;113(1):65-73. doi: 10.1172/JCI18699. J Clin Invest. 2004. PMID: 14702110 Free PMC article.

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