Lévesque JP - Search Results

1

Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs.

Winkler IG, Sims NA, Pettit AR, Barbier V, Nowlan B, Helwani F, Poulton IJ, van Rooijen N, Alexander KA, Raggatt LJ, Lévesque JP. Winkler IG, et al. Among authors: levesque jp. Blood. 2010 Dec 2;116(23):4815-28. doi: 10.1182/blood-2009-11-253534. Epub 2010 Aug 16. Blood. 2010. PMID: 20713966 Free article.

2

Mobilization by either cyclophosphamide or granulocyte colony-stimulating factor transforms the bone marrow into a highly proteolytic environment.

Lévesque JP, Hendy J, Takamatsu Y, Williams B, Winkler IG, Simmons PJ. Lévesque JP, et al. Exp Hematol. 2002 May;30(5):440-9. doi: 10.1016/s0301-472x(02)00788-9. Exp Hematol. 2002. PMID: 12031650 Free article.

3

Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide.

Lévesque JP, Hendy J, Takamatsu Y, Simmons PJ, Bendall LJ. Lévesque JP, et al. J Clin Invest. 2003 Jan;111(2):187-96. doi: 10.1172/JCI15994. J Clin Invest. 2003. PMID: 12531874 Free PMC article.

4

Granulocyte colony-stimulating factor induces the release in the bone marrow of proteases that cleave c-KIT receptor (CD117) from the surface of hematopoietic progenitor cells.

Lévesque JP, Hendy J, Winkler IG, Takamatsu Y, Simmons PJ. Lévesque JP, et al. Exp Hematol. 2003 Feb;31(2):109-17. doi: 10.1016/s0301-472x(02)01028-7. Exp Hematol. 2003. PMID: 12591275 Free article.

5

Adhesion to E-selectin promotes growth inhibition and apoptosis of human and murine hematopoietic progenitor cells independent of PSGL-1.

Winkler IG, Snapp KR, Simmons PJ, Lévesque JP. Winkler IG, et al. Among authors: levesque jp. Blood. 2004 Mar 1;103(5):1685-92. doi: 10.1182/blood-2003-06-1921. Epub 2003 Oct 30. Blood. 2004. PMID: 14592840 Free article.

6

Characterization of hematopoietic progenitor mobilization in protease-deficient mice.

Levesque JP, Liu F, Simmons PJ, Betsuyaku T, Senior RM, Pham C, Link DC. Levesque JP, et al. Blood. 2004 Jul 1;104(1):65-72. doi: 10.1182/blood-2003-05-1589. Epub 2004 Mar 9. Blood. 2004. PMID: 15010367 Free article.

7

Contrasting effects of P-selectin and E-selectin on the differentiation of murine hematopoietic progenitor cells.

Eto T, Winkler I, Purton LE, Lévesque JP. Eto T, et al. Among authors: levesque jp. Exp Hematol. 2005 Feb;33(2):232-42. doi: 10.1016/j.exphem.2004.10.018. Exp Hematol. 2005. PMID: 15676218 Free article.

8

Serine protease inhibitors serpina1 and serpina3 are down-regulated in bone marrow during hematopoietic progenitor mobilization.

Winkler IG, Hendy J, Coughlin P, Horvath A, Lévesque JP. Winkler IG, et al. Among authors: levesque jp. J Exp Med. 2005 Apr 4;201(7):1077-88. doi: 10.1084/jem.20042299. Epub 2005 Mar 28. J Exp Med. 2005. PMID: 15795238 Free PMC article.

9

G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow.

Semerad CL, Christopher MJ, Liu F, Short B, Simmons PJ, Winkler I, Levesque JP, Chappel J, Ross FP, Link DC. Semerad CL, et al. Among authors: levesque jp. Blood. 2005 Nov 1;106(9):3020-7. doi: 10.1182/blood-2004-01-0272. Epub 2005 Jul 21. Blood. 2005. PMID: 16037394 Free PMC article.

10

Mechanisms of hematopoietic stem cell mobilization: when innate immunity assails the cells that make blood and bone.

Winkler IG, Lévesque JP. Winkler IG, et al. Among authors: levesque jp. Exp Hematol. 2006 Aug;34(8):996-1009. doi: 10.1016/j.exphem.2006.04.005. Exp Hematol. 2006. PMID: 16863906 Free article. Review.

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