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703 results

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Page 1
Novel pyrrolidine heterocycles as CCR1 antagonists.
Merritt JR, James R, Paradkar VM, Zhang C, Liu R, Liu J, Jacob B, Chiriac C, Ohlmeyer MJ, Quadros E, Wines P, Postelnek J, Hicks CM, Chen W, Kimble EF, O'Brien L, White N, Desai H, Appell KC, Webb ML. Merritt JR, et al. Among authors: desai h. Bioorg Med Chem Lett. 2010 Sep 15;20(18):5477-9. doi: 10.1016/j.bmcl.2010.07.082. Epub 2010 Jul 24. Bioorg Med Chem Lett. 2010. PMID: 20708929
Novel pyrrolidine ureas as C-C chemokine receptor 1 (CCR1) antagonists.
Merritt JR, Liu J, Quadros E, Morris ML, Liu R, Zhang R, Jacob B, Postelnek J, Hicks CM, Chen W, Kimble EF, Rogers WL, O'Brien L, White N, Desai H, Bansal S, King G, Ohlmeyer MJ, Appell KC, Webb ML. Merritt JR, et al. Among authors: desai h. J Med Chem. 2009 Mar 12;52(5):1295-301. doi: 10.1021/jm801416q. J Med Chem. 2009. PMID: 19183043
Discovery of novel quinolinone adenosine A2B antagonists.
McGuinness BF, Ho KK, Stauffer TM, Rokosz LL, Mannava N, Kultgen SG, Saionz K, Klon A, Chen W, Desai H, Rogers WL, Webb M, Yin J, Jiang Y, Li T, Yan H, Jing K, Zhang S, Majumdar KK, Srivastava V, Saha S. McGuinness BF, et al. Among authors: desai h. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7414-20. doi: 10.1016/j.bmcl.2010.10.030. Epub 2010 Nov 4. Bioorg Med Chem Lett. 2010. PMID: 21055932
Identification and optimization of novel 2-(4-oxo-2-aryl-quinazolin-3(4H)-yl)acetamide vasopressin V3 (V1b) receptor antagonists.
Letourneau JJ, Riviello CM, Li H, Cole AG, Ho KK, Zanetakos HA, Desai H, Zhao J, Auld DS, Napier SE, Thomson FJ, Goan KA, Morphy JR, Ohlmeyer MH, Webb ML. Letourneau JJ, et al. Among authors: desai h. Bioorg Med Chem Lett. 2010 Sep 15;20(18):5394-7. doi: 10.1016/j.bmcl.2010.07.118. Epub 2010 Aug 1. Bioorg Med Chem Lett. 2010. PMID: 20719508
Synthesis and SAR studies of novel 2-(4-oxo-2-aryl-quinazolin-3(4H)-yl)acetamide vasopressin V1b receptor antagonists.
Napier SE, Letourneau JJ, Ansari N, Auld DS, Baker J, Best S, Campbell-Wan L, Chan JH, Craighead M, Desai H, Goan KA, Ho KK, Hulskotte EG, MacSweeney CP, Milne R, Morphy JR, Neagu I, Ohlmeyer MH, Peeters AW, Presland J, Riviello C, Ruigt GS, Thomson FJ, Zanetakos HA, Zhao J, Webb ML. Napier SE, et al. Among authors: desai h. Bioorg Med Chem Lett. 2011 Mar 15;21(6):1871-5. doi: 10.1016/j.bmcl.2010.12.081. Epub 2010 Dec 21. Bioorg Med Chem Lett. 2011. PMID: 21353540
Synthesis and SAR studies of novel 2-(6-aminomethylaryl-2-aryl-4-oxo-quinazolin-3(4H)-yl)acetamide vasopressin V1b receptor antagonists.
Napier SE, Letourneau JJ, Ansari N, Auld DS, Baker J, Best S, Campbell-Wan L, Chan R, Craighead M, Desai H, Ho KK, MacSweeney C, Milne R, Richard Morphy J, Neagu I, Ohlmeyer MH, Pick J, Presland J, Riviello C, Zanetakos HA, Zhao J, Webb ML. Napier SE, et al. Among authors: desai h. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3813-7. doi: 10.1016/j.bmcl.2011.04.022. Epub 2011 Apr 13. Bioorg Med Chem Lett. 2011. PMID: 21596563
703 results