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SIK2 is a centrosome kinase required for bipolar mitotic spindle formation that provides a potential target for therapy in ovarian cancer.
Ahmed AA, Lu Z, Jennings NB, Etemadmoghadam D, Capalbo L, Jacamo RO, Barbosa-Morais N, Le XF; Australian Ovarian Cancer Study Group; Vivas-Mejia P, Lopez-Berestein G, Grandjean G, Bartholomeusz G, Liao W, Andreeff M, Bowtell D, Glover DM, Sood AK, Bast RC Jr. Ahmed AA, et al. Among authors: lu z. Cancer Cell. 2010 Aug 9;18(2):109-21. doi: 10.1016/j.ccr.2010.06.018. Cancer Cell. 2010. PMID: 20708153 Free PMC article.
Prevention and early detection of ovarian cancer: mission impossible?
Bast RC Jr, Brewer M, Zou C, Hernandez MA, Daley M, Ozols R, Lu K, Lu Z, Badgwell D, Mills GB, Skates S, Zhang Z, Chan D, Lokshin A, Yu Y. Bast RC Jr, et al. Among authors: lu z, lu k. Recent Results Cancer Res. 2007;174:91-100. doi: 10.1007/978-3-540-37696-5_9. Recent Results Cancer Res. 2007. PMID: 17302189 Review.
Urinary mesothelin provides greater sensitivity for early stage ovarian cancer than serum mesothelin, urinary hCG free beta subunit and urinary hCG beta core fragment.
Badgwell D, Lu Z, Cole L, Fritsche H, Atkinson EN, Somers E, Allard J, Moore RG, Lu KH, Bast RC Jr. Badgwell D, et al. Among authors: lu z, lu kh. Gynecol Oncol. 2007 Sep;106(3):490-7. doi: 10.1016/j.ygyno.2007.04.022. Epub 2007 May 25. Gynecol Oncol. 2007. PMID: 17532030 Free PMC article.
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