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The hormone replacement therapy drug tibolone acts very similar to medroxyprogesterone acetate in an estrogen-and progesterone-responsive endometrial cancer cell line.
Hanifi-Moghaddam P, Sijmons B, Ott MC, van Ijcken WF, Nowzari D, Kuhne EC, van der Spek P, Kloosterboer HJ, Burger CW, Blok LJ. Hanifi-Moghaddam P, et al. Among authors: van ijcken wf, van der spek p. J Mol Endocrinol. 2006 Dec;37(3):405-13. doi: 10.1677/jme.1.02057. J Mol Endocrinol. 2006. PMID: 17170081
HPV related VIN: highly proliferative and diminished responsiveness to extracellular signals.
Santegoets LA, Seters Mv, Helmerhorst TJ, Heijmans-Antonissen C, Hanifi-Moghaddam P, Ewing PC, van Ijcken WF, van der Spek PJ, van der Meijden WI, Blok LJ. Santegoets LA, et al. Among authors: van der spek pj, van ijcken wf, van der meijden wi. Int J Cancer. 2007 Aug 15;121(4):759-66. doi: 10.1002/ijc.22769. Int J Cancer. 2007. PMID: 17471573
Difference in signalling between various hormone therapies in endometrium, myometrium and upper part of the vagina.
Hanifi-Moghaddam P, Boers-Sijmons B, Klaassens AH, van Wijk FH, Van Ijcken WF, Van der Spek P, Verheul HA, Kloosterboer HJ, Burger CW, Blok LJ. Hanifi-Moghaddam P, et al. Among authors: van wijk fh, van ijcken wf, van der spek p. Hum Reprod. 2008 Feb;23(2):298-305. doi: 10.1093/humrep/dem366. Epub 2007 Dec 11. Hum Reprod. 2008. PMID: 18077316 Clinical Trial.
Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene.
Kayser M, Liu F, Janssens AC, Rivadeneira F, Lao O, van Duijn K, Vermeulen M, Arp P, Jhamai MM, van Ijcken WF, den Dunnen JT, Heath S, Zelenika D, Despriet DD, Klaver CC, Vingerling JR, de Jong PT, Hofman A, Aulchenko YS, Uitterlinden AG, Oostra BA, van Duijn CM. Kayser M, et al. Among authors: van duijn k, van duijn cm, van ijcken wf. Am J Hum Genet. 2008 Feb;82(2):411-23. doi: 10.1016/j.ajhg.2007.10.003. Epub 2008 Jan 25. Am J Hum Genet. 2008. PMID: 18252221 Free PMC article.
Physiological thyroid hormone levels regulate numerous skeletal muscle transcripts.
Visser WE, Heemstra KA, Swagemakers SM, Ozgür Z, Corssmit EP, Burggraaf J, van Ijcken WF, van der Spek PJ, Smit JW, Visser TJ. Visser WE, et al. Among authors: van der spek pj, van ijcken wf. J Clin Endocrinol Metab. 2009 Sep;94(9):3487-96. doi: 10.1210/jc.2009-0782. Epub 2009 Jun 30. J Clin Endocrinol Metab. 2009. PMID: 19567520
Unacylated ghrelin rapidly modulates lipogenic and insulin signaling pathway gene expression in metabolically active tissues of GHSR deleted mice.
Delhanty PJ, Sun Y, Visser JA, van Kerkwijk A, Huisman M, van Ijcken WF, Swagemakers S, Smith RG, Themmen AP, van der Lely AJ. Delhanty PJ, et al. Among authors: van ijcken wf, van der lely aj, van kerkwijk a. PLoS One. 2010 Jul 26;5(7):e11749. doi: 10.1371/journal.pone.0011749. PLoS One. 2010. PMID: 20668691 Free PMC article.
Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin.
Borg J, Papadopoulos P, Georgitsi M, Gutiérrez L, Grech G, Fanis P, Phylactides M, Verkerk AJ, van der Spek PJ, Scerri CA, Cassar W, Galdies R, van Ijcken W, Ozgür Z, Gillemans N, Hou J, Bugeja M, Grosveld FG, von Lindern M, Felice AE, Patrinos GP, Philipsen S. Borg J, et al. Nat Genet. 2010 Sep;42(9):801-5. doi: 10.1038/ng.630. Epub 2010 Aug 1. Nat Genet. 2010. PMID: 20676099 Free PMC article.
285 results