Towle HC - Search Results

1

Activation and repression of glucose-stimulated ChREBP requires the concerted action of multiple domains within the MondoA conserved region.

Davies MN, O'Callaghan BL, Towle HC. Davies MN, et al. Among authors: towle hc. Am J Physiol Endocrinol Metab. 2010 Oct;299(4):E665-74. doi: 10.1152/ajpendo.00349.2010. Epub 2010 Aug 3. Am J Physiol Endocrinol Metab. 2010. PMID: 20682844 Free PMC article.

2

Identification and function of phosphorylation in the glucose-regulated transcription factor ChREBP.

Tsatsos NG, Davies MN, O'Callaghan BL, Towle HC. Tsatsos NG, et al. Among authors: towle hc. Biochem J. 2008 Apr 15;411(2):261-70. doi: 10.1042/BJ20071156. Biochem J. 2008. PMID: 18215143

3

Glucose activates ChREBP by increasing its rate of nuclear entry and relieving repression of its transcriptional activity.

Davies MN, O'Callaghan BL, Towle HC. Davies MN, et al. Among authors: towle hc. J Biol Chem. 2008 Aug 29;283(35):24029-38. doi: 10.1074/jbc.M801539200. Epub 2008 Jun 30. J Biol Chem. 2008. PMID: 18591247 Free PMC article.

4

Overlapping roles of the glucose-responsive genes, S14 and S14R, in hepatic lipogenesis.

Aipoalani DL, O'Callaghan BL, Mashek DG, Mariash CN, Towle HC. Aipoalani DL, et al. Among authors: towle hc. Endocrinology. 2010 May;151(5):2071-7. doi: 10.1210/en.2009-1058. Epub 2010 Mar 16. Endocrinology. 2010. PMID: 20233797 Free PMC article.

5

Glucose regulation of the acetyl-CoA carboxylase promoter PI in rat hepatocytes.

O'Callaghan BL, Koo SH, Wu Y, Freake HC, Towle HC. O'Callaghan BL, et al. Among authors: towle hc. J Biol Chem. 2001 May 11;276(19):16033-9. doi: 10.1074/jbc.M101557200. Epub 2001 Feb 28. J Biol Chem. 2001. PMID: 11340083 Free article.

6

Glucose activation of ChREBP in hepatocytes occurs via a two-step mechanism.

Tsatsos NG, Towle HC. Tsatsos NG, et al. Among authors: towle hc. Biochem Biophys Res Commun. 2006 Feb 10;340(2):449-56. doi: 10.1016/j.bbrc.2005.12.029. Epub 2005 Dec 15. Biochem Biophys Res Commun. 2006. PMID: 16375857

7

Glucose as a regulator of eukaryotic gene transcription.

Towle HC. Towle HC. Trends Endocrinol Metab. 2005 Dec;16(10):489-94. doi: 10.1016/j.tem.2005.10.003. Epub 2005 Nov 2. Trends Endocrinol Metab. 2005. PMID: 16269245 Review.

8

Direct role of ChREBP.Mlx in regulating hepatic glucose-responsive genes.

Ma L, Tsatsos NG, Towle HC. Ma L, et al. Among authors: towle hc. J Biol Chem. 2005 Mar 25;280(12):12019-27. doi: 10.1074/jbc.M413063200. Epub 2005 Jan 20. J Biol Chem. 2005. PMID: 15664996 Free article.

9

ChREBP*Mlx is the principal mediator of glucose-induced gene expression in the liver.

Ma L, Robinson LN, Towle HC. Ma L, et al. Among authors: towle hc. J Biol Chem. 2006 Sep 29;281(39):28721-30. doi: 10.1074/jbc.M601576200. Epub 2006 Aug 2. J Biol Chem. 2006. PMID: 16885160 Free article.

10

A critical role for the loop region of the basic helix-loop-helix/leucine zipper protein Mlx in DNA binding and glucose-regulated transcription.

Ma L, Sham YY, Walters KJ, Towle HC. Ma L, et al. Among authors: towle hc. Nucleic Acids Res. 2007;35(1):35-44. doi: 10.1093/nar/gkl987. Epub 2006 Dec 5. Nucleic Acids Res. 2007. PMID: 17148476 Free PMC article.

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