Ambrus G - Search Results

1

Identification of a small molecule inhibitor of importin β mediated nuclear import by confocal on-bead screening of tagged one-bead one-compound libraries.

Hintersteiner M, Ambrus G, Bednenko J, Schmied M, Knox AJ, Meisner NC, Gstach H, Seifert JM, Singer EL, Gerace L, Auer M. Hintersteiner M, et al. Among authors: ambrus g. ACS Chem Biol. 2010 Oct 15;5(10):967-79. doi: 10.1021/cb100094k. ACS Chem Biol. 2010. PMID: 20677820 Free PMC article.

2

Small molecule peptidomimetic inhibitors of importin α/β mediated nuclear transport.

Ambrus G, Whitby LR, Singer EL, Trott O, Choi E, Olson AJ, Boger DL, Gerace L. Ambrus G, et al. Bioorg Med Chem. 2010 Nov 1;18(21):7611-20. doi: 10.1016/j.bmc.2010.08.038. Epub 2010 Aug 21. Bioorg Med Chem. 2010. PMID: 20869252 Free PMC article.

3

The structure of the NXF2/NXT1 heterodimeric complex reveals the combined specificity and versatility of the NTF2-like fold.

Kerkow DE, Carmel AB, Menichelli E, Ambrus G, Hills RD Jr, Gerace L, Williamson JR. Kerkow DE, et al. Among authors: ambrus g. J Mol Biol. 2012 Jan 27;415(4):649-65. doi: 10.1016/j.jmb.2011.11.027. Epub 2011 Nov 22. J Mol Biol. 2012. PMID: 22123199 Free PMC article.

4

Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production.

Naji S, Ambrus G, Cimermančič P, Reyes JR, Johnson JR, Filbrandt R, Huber MD, Vesely P, Krogan NJ, Yates JR 3rd, Saphire AC, Gerace L. Naji S, et al. Among authors: ambrus g. Mol Cell Proteomics. 2012 Apr;11(4):M111.015313. doi: 10.1074/mcp.M111.015313. Epub 2011 Dec 15. Mol Cell Proteomics. 2012. PMID: 22174317 Free PMC article.

5

A fragment-based approach to identifying S-adenosyl-l-methionine -competitive inhibitors of catechol O-methyl transferase (COMT).

Lanier M, Ambrus G, Cole DC, Davenport R, Ellery J, Fosbeary R, Jennings AJ, Kadotani A, Kamada Y, Kamran R, Matsumoto S, Mizukami A, Okubo S, Okada K, Saikatendu K, Walsh L, Wu H, Hixon MS. Lanier M, et al. Among authors: ambrus g. J Med Chem. 2014 Jun 26;57(12):5459-63. doi: 10.1021/jm500475k. Epub 2014 Jun 4. J Med Chem. 2014. PMID: 24847974

6

Synthesis and evaluation of 2-[(5-methylbenz-1-ox-4-azin-6-yl)imino]imidazoline, a potent, peripherally acting alpha 2 adrenoceptor agonist.

Munk SA, Harcourt D, Ambrus G, Denys L, Gluchowski C, Burke JA, Kharlamb AB, Manlapaz CA, Padillo EU, Runde E, Williams L, Wheeler LA, Garst ME. Munk SA, et al. Among authors: ambrus g. J Med Chem. 1996 Aug 30;39(18):3533-8. doi: 10.1021/jm960359r. J Med Chem. 1996. PMID: 8784451

7

A neural network based classification scheme for cytotoxicity predictions:Validation on 30,000 compounds.

Molnár L, Keseru GM, Papp A, Lorincz Z, Ambrus G, Darvas F. Molnár L, et al. Among authors: ambrus g. Bioorg Med Chem Lett. 2006 Feb 15;16(4):1037-9. doi: 10.1016/j.bmcl.2005.10.079. Epub 2005 Nov 8. Bioorg Med Chem Lett. 2006. PMID: 16288868

8

Shared neural codes of recognition memory.

Ambrus GG. Ambrus GG. Sci Rep. 2024 Jul 9;14(1):15846. doi: 10.1038/s41598-024-66158-y. Sci Rep. 2024. PMID: 38982142 Free PMC article.

9

Your place or mine? The neural dynamics of personally familiar scene recognition suggests category independent familiarity encoding.

Klink H, Kaiser D, Stecher R, Ambrus GG, Kovács G. Klink H, et al. Among authors: ambrus gg. Cereb Cortex. 2023 Dec 9;33(24):11634-11645. doi: 10.1093/cercor/bhad397. Cereb Cortex. 2023. PMID: 37885126

10

A rapid solid form risk assessment workflow for ophthalmic drug candidates.

Wu K, Ambrus G. Wu K, et al. Among authors: ambrus g. Drug Dev Ind Pharm. 2023 Jun;49(6):429-437. doi: 10.1080/03639045.2023.2223288. Epub 2023 Jun 22. Drug Dev Ind Pharm. 2023. PMID: 37305975

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