Gillemans N - Search Results

1

Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin.

Borg J, Papadopoulos P, Georgitsi M, Gutiérrez L, Grech G, Fanis P, Phylactides M, Verkerk AJ, van der Spek PJ, Scerri CA, Cassar W, Galdies R, van Ijcken W, Ozgür Z, Gillemans N, Hou J, Bugeja M, Grosveld FG, von Lindern M, Felice AE, Patrinos GP, Philipsen S. Borg J, et al. Among authors: gillemans n. Nat Genet. 2010 Sep;42(9):801-5. doi: 10.1038/ng.630. Epub 2010 Aug 1. Nat Genet. 2010. PMID: 20676099 Free PMC article.

2

The human beta-globin locus control region confers an early embryonic erythroid-specific expression pattern to a basic promoter driving the bacterial lacZ gene.

Tewari R, Gillemans N, Harper A, Wijgerde M, Zafarana G, Drabek D, Grosveld F, Philipsen S. Tewari R, et al. Among authors: gillemans n. Development. 1996 Dec;122(12):3991-9. doi: 10.1242/dev.122.12.3991. Development. 1996. PMID: 9012519

3

Erythroid Krüppel-like factor (EKLF) is active in primitive and definitive erythroid cells and is required for the function of 5'HS3 of the beta-globin locus control region.

Tewari R, Gillemans N, Wijgerde M, Nuez B, von Lindern M, Grosveld F, Philipsen S. Tewari R, et al. Among authors: gillemans n. EMBO J. 1998 Apr 15;17(8):2334-41. doi: 10.1093/emboj/17.8.2334. EMBO J. 1998. PMID: 9545245 Free PMC article.

4

The level of the tissue-specific factor GATA-1 affects the cell-cycle machinery.

Whyatt DJ, Karis A, Harkes IC, Verkerk A, Gillemans N, Elefanty AG, Vairo G, Ploemacher R, Grosveld F, Philipsen S. Whyatt DJ, et al. Among authors: gillemans n. Genes Funct. 1997 Feb;1(1):11-24. doi: 10.1046/j.1365-4624.1997.00003.x. Genes Funct. 1997. PMID: 9680325

5

Altered DNA-binding specificity mutants of EKLF and Sp1 show that EKLF is an activator of the beta-globin locus control region in vivo.

Gillemans N, Tewari R, Lindeboom F, Rottier R, de Wit T, Wijgerde M, Grosveld F, Philipsen S. Gillemans N, et al. Genes Dev. 1998 Sep 15;12(18):2863-73. doi: 10.1101/gad.12.18.2863. Genes Dev. 1998. PMID: 9744863 Free PMC article.

6

Functional and comparative analysis of globin loci in pufferfish and humans.

Gillemans N, McMorrow T, Tewari R, Wai AW, Burgtorf C, Drabek D, Ventress N, Langeveld A, Higgs D, Tan-Un K, Grosveld F, Philipsen S. Gillemans N, et al. Blood. 2003 Apr 1;101(7):2842-9. doi: 10.1182/blood-2002-09-2850. Epub 2002 Nov 27. Blood. 2003. PMID: 12517812 Free article.

7

HS5 of the human beta-globin locus control region: a developmental stage-specific border in erythroid cells.

Wai AW, Gillemans N, Raguz-Bolognesi S, Pruzina S, Zafarana G, Meijer D, Philipsen S, Grosveld F. Wai AW, et al. Among authors: gillemans n. EMBO J. 2003 Sep 1;22(17):4489-500. doi: 10.1093/emboj/cdg437. EMBO J. 2003. PMID: 12941700 Free PMC article.

8

A tissue-specific knockout reveals that Gata1 is not essential for Sertoli cell function in the mouse.

Lindeboom F, Gillemans N, Karis A, Jaegle M, Meijer D, Grosveld F, Philipsen S. Lindeboom F, et al. Among authors: gillemans n. Nucleic Acids Res. 2003 Sep 15;31(18):5405-12. doi: 10.1093/nar/gkg723. Nucleic Acids Res. 2003. PMID: 12954777 Free PMC article.

9

The active spatial organization of the beta-globin locus requires the transcription factor EKLF.

Drissen R, Palstra RJ, Gillemans N, Splinter E, Grosveld F, Philipsen S, de Laat W. Drissen R, et al. Among authors: gillemans n. Genes Dev. 2004 Oct 15;18(20):2485-90. doi: 10.1101/gad.317004. Genes Dev. 2004. PMID: 15489291 Free PMC article.

10

Dynamic regulation of Gata factor levels is more important than their identity.

Ferreira R, Wai A, Shimizu R, Gillemans N, Rottier R, von Lindern M, Ohneda K, Grosveld F, Yamamoto M, Philipsen S. Ferreira R, et al. Among authors: gillemans n. Blood. 2007 Jun 15;109(12):5481-90. doi: 10.1182/blood-2006-11-060491. Epub 2007 Feb 27. Blood. 2007. PMID: 17327407 Free article.

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