Basu R - Search Results

1

Early activation of matrix metalloproteinases underlies the exacerbated systolic and diastolic dysfunction in mice lacking TIMP3 following myocardial infarction.

Kandalam V, Basu R, Abraham T, Wang X, Awad A, Wang W, Lopaschuk GD, Maeda N, Oudit GY, Kassiri Z. Kandalam V, et al. Among authors: basu r. Am J Physiol Heart Circ Physiol. 2010 Oct;299(4):H1012-23. doi: 10.1152/ajpheart.00246.2010. Epub 2010 Jul 30. Am J Physiol Heart Circ Physiol. 2010. PMID: 20675565 Free PMC article.

2

Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function.

Basu R, Oudit GY, Wang X, Zhang L, Ussher JR, Lopaschuk GD, Kassiri Z. Basu R, et al. Am J Physiol Heart Circ Physiol. 2009 Dec;297(6):H2096-108. doi: 10.1152/ajpheart.00452.2009. Epub 2009 Oct 2. Am J Physiol Heart Circ Physiol. 2009. PMID: 19801494 Free article.

3

Loss of angiotensin-converting enzyme 2 accelerates maladaptive left ventricular remodeling in response to myocardial infarction.

Kassiri Z, Zhong J, Guo D, Basu R, Wang X, Liu PP, Scholey JW, Penninger JM, Oudit GY. Kassiri Z, et al. Among authors: basu r. Circ Heart Fail. 2009 Sep;2(5):446-55. doi: 10.1161/CIRCHEARTFAILURE.108.840124. Epub 2009 Jun 15. Circ Heart Fail. 2009. PMID: 19808375

4

TIMP2 deficiency accelerates adverse post-myocardial infarction remodeling because of enhanced MT1-MMP activity despite lack of MMP2 activation.

Kandalam V, Basu R, Abraham T, Wang X, Soloway PD, Jaworski DM, Oudit GY, Kassiri Z. Kandalam V, et al. Among authors: basu r. Circ Res. 2010 Mar 5;106(4):796-808. doi: 10.1161/CIRCRESAHA.109.209189. Epub 2010 Jan 7. Circ Res. 2010. PMID: 20056917

5

Loss of PI3Kγ enhances cAMP-dependent MMP remodeling of the myocardial N-cadherin adhesion complexes and extracellular matrix in response to early biomechanical stress.

Guo D, Kassiri Z, Basu R, Chow FL, Kandalam V, Damilano F, Liang W, Izumo S, Hirsch E, Penninger JM, Backx PH, Oudit GY. Guo D, et al. Among authors: basu r. Circ Res. 2010 Nov 12;107(10):1275-89. doi: 10.1161/CIRCRESAHA.110.229054. Epub 2010 Sep 16. Circ Res. 2010. PMID: 20847309

6

Tissue inhibitor of metalloproteinases (TIMPs) in heart failure.

Moore L, Fan D, Basu R, Kandalam V, Kassiri Z. Moore L, et al. Among authors: basu r. Heart Fail Rev. 2012 Sep;17(4-5):693-706. doi: 10.1007/s10741-011-9266-y. Heart Fail Rev. 2012. PMID: 21717224 Review.

7

Lack of tissue inhibitor of metalloproteinases 2 leads to exacerbated left ventricular dysfunction and adverse extracellular matrix remodeling in response to biomechanical stress.

Kandalam V, Basu R, Moore L, Fan D, Wang X, Jaworski DM, Oudit GY, Kassiri Z. Kandalam V, et al. Among authors: basu r. Circulation. 2011 Nov 8;124(19):2094-105. doi: 10.1161/CIRCULATIONAHA.111.030338. Epub 2011 Oct 10. Circulation. 2011. PMID: 21986284

8

Loss of TIMP3 selectively exacerbates diabetic nephropathy.

Basu R, Lee J, Wang Z, Patel VB, Fan D, Das SK, Liu GC, John R, Scholey JW, Oudit GY, Kassiri Z. Basu R, et al. Am J Physiol Renal Physiol. 2012 Nov 1;303(9):F1341-52. doi: 10.1152/ajprenal.00349.2012. Epub 2012 Aug 15. Am J Physiol Renal Physiol. 2012. PMID: 22896043 Free PMC article.

9

Loss of Timp3 gene leads to abdominal aortic aneurysm formation in response to angiotensin II.

Basu R, Fan D, Kandalam V, Lee J, Das SK, Wang X, Baldwin TA, Oudit GY, Kassiri Z. Basu R, et al. J Biol Chem. 2012 Dec 28;287(53):44083-96. doi: 10.1074/jbc.M112.425652. Epub 2012 Nov 9. J Biol Chem. 2012. PMID: 23144462 Free PMC article.

10

TIMP3 is the primary TIMP to regulate agonist-induced vascular remodelling and hypertension.

Basu R, Lee J, Morton JS, Takawale A, Fan D, Kandalam V, Wang X, Davidge ST, Kassiri Z. Basu R, et al. Cardiovasc Res. 2013 Jun 1;98(3):360-71. doi: 10.1093/cvr/cvt067. Epub 2013 Mar 21. Cardiovasc Res. 2013. PMID: 23524300

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