Bauman DR - Search Results

1

Non-stereo-selective cytosolic human brain tissue 3-ketosteroid reductase is refractory to inhibition by AKR1C inhibitors.

Steckelbroeck S, Lütjohann D, Bauman DR, Ludwig M, Friedl A, Hans VH, Penning TM, Klingmüller D. Steckelbroeck S, et al. Among authors: bauman dr. Biochim Biophys Acta. 2010 Nov;1801(11):1221-31. doi: 10.1016/j.bbalip.2010.07.005. Epub 2010 Jul 29. Biochim Biophys Acta. 2010. PMID: 20673851 Free PMC article.

2

Human type 3 3alpha-hydroxysteroid dehydrogenase (aldo-keto reductase 1C2) and androgen metabolism in prostate cells.

Rizner TL, Lin HK, Peehl DM, Steckelbroeck S, Bauman DR, Penning TM. Rizner TL, et al. Among authors: bauman dr. Endocrinology. 2003 Jul;144(7):2922-32. doi: 10.1210/en.2002-0032. Endocrinology. 2003. PMID: 12810547

3

Aldo-keto reductase (AKR) 1C3: role in prostate disease and the development of specific inhibitors.

Penning TM, Steckelbroeck S, Bauman DR, Miller MW, Jin Y, Peehl DM, Fung KM, Lin HK. Penning TM, et al. Among authors: bauman dr. Mol Cell Endocrinol. 2006 Mar 27;248(1-2):182-91. doi: 10.1016/j.mce.2005.12.009. Epub 2006 Jan 18. Mol Cell Endocrinol. 2006. PMID: 16417966

4

Transcript profiling of the androgen signal in normal prostate, benign prostatic hyperplasia, and prostate cancer.

Bauman DR, Steckelbroeck S, Peehl DM, Penning TM. Bauman DR, et al. Endocrinology. 2006 Dec;147(12):5806-16. doi: 10.1210/en.2006-0627. Epub 2006 Sep 7. Endocrinology. 2006. PMID: 16959841

5

Identification of the major oxidative 3alpha-hydroxysteroid dehydrogenase in human prostate that converts 5alpha-androstane-3alpha,17beta-diol to 5alpha-dihydrotestosterone: a potential therapeutic target for androgen-dependent disease.

Bauman DR, Steckelbroeck S, Williams MV, Peehl DM, Penning TM. Bauman DR, et al. Mol Endocrinol. 2006 Feb;20(2):444-58. doi: 10.1210/me.2005-0287. Epub 2005 Sep 22. Mol Endocrinol. 2006. PMID: 16179381

6

Identification of the molecular switch that regulates access of 5alpha-DHT to the androgen receptor.

Penning TM, Bauman DR, Jin Y, Rizner TL. Penning TM, et al. Among authors: bauman dr. Mol Cell Endocrinol. 2007 Feb;265-266:77-82. doi: 10.1016/j.mce.2006.12.007. Epub 2007 Jan 16. Mol Cell Endocrinol. 2007. PMID: 17223255 Free PMC article. Review.

7

Pre-receptor regulation of the androgen receptor.

Penning TM, Jin Y, Rizner TL, Bauman DR. Penning TM, et al. Among authors: bauman dr. Mol Cell Endocrinol. 2008 Jan 16;281(1-2):1-8. doi: 10.1016/j.mce.2007.10.008. Epub 2007 Oct 22. Mol Cell Endocrinol. 2008. PMID: 18060684 Free PMC article. Review.

8

The roles of aldo-keto reductases in steroid hormone action.

Bauman DR, Steckelbroeck S, Penning TM. Bauman DR, et al. Drug News Perspect. 2004 Nov;17(9):563-78. doi: 10.1358/dnp.2004.17.9.872570. Drug News Perspect. 2004. PMID: 15645014 Review.

9

Fluorogenic metabolic probes for direct activity readout of redox enzymes: Selective measurement of human AKR1C2 in living cells.

Yee DJ, Balsanek V, Bauman DR, Penning TM, Sames D. Yee DJ, et al. Among authors: bauman dr. Proc Natl Acad Sci U S A. 2006 Sep 5;103(36):13304-9. doi: 10.1073/pnas.0604672103. Epub 2006 Aug 28. Proc Natl Acad Sci U S A. 2006. PMID: 16938874 Free PMC article.

10

Development of nonsteroidal anti-inflammatory drug analogs and steroid carboxylates selective for human aldo-keto reductase isoforms: potential antineoplastic agents that work independently of cyclooxygenase isozymes.

Bauman DR, Rudnick SI, Szewczuk LM, Jin Y, Gopishetty S, Penning TM. Bauman DR, et al. Mol Pharmacol. 2005 Jan;67(1):60-8. doi: 10.1124/mol.104.006569. Epub 2004 Oct 8. Mol Pharmacol. 2005. PMID: 15475569

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