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Cord blood natural killer cells exhibit impaired lytic immunological synapse formation that is reversed with IL-2 exvivo expansion.
Xing D, Ramsay AG, Gribben JG, Decker WK, Burks JK, Munsell M, Li S, Robinson SN, Yang H, Steiner D, Shah N, McMannis JD, Champlin RE, Hosing C, Zweidler-McKay PA, Shpall EJ, Bollard CM. Xing D, et al. J Immunother. 2010 Sep;33(7):684-96. doi: 10.1097/CJI.0b013e3181e475e9. J Immunother. 2010. PMID: 20664358 Free PMC article.
Pronounced hypoxia in models of murine and human leukemia: high efficacy of hypoxia-activated prodrug PR-104.
Benito J, Shi Y, Szymanska B, Carol H, Boehm I, Lu H, Konoplev S, Fang W, Zweidler-McKay PA, Campana D, Borthakur G, Bueso-Ramos C, Shpall E, Thomas DA, Jordan CT, Kantarjian H, Wilson WR, Lock R, Andreeff M, Konopleva M. Benito J, et al. PLoS One. 2011;6(8):e23108. doi: 10.1371/journal.pone.0023108. Epub 2011 Aug 11. PLoS One. 2011. PMID: 21853076 Free PMC article.
Ex vivo fucosylation improves human cord blood engraftment in NOD-SCID IL-2Rγ(null) mice.
Robinson SN, Simmons PJ, Thomas MW, Brouard N, Javni JA, Trilok S, Shim JS, Yang H, Steiner D, Decker WK, Xing D, Shultz LD, Savoldo B, Dotti G, Bollard CM, Miller L, Champlin RE, Shpall EJ, Zweidler-McKay PA. Robinson SN, et al. Exp Hematol. 2012 Jun;40(6):445-56. doi: 10.1016/j.exphem.2012.01.015. Epub 2012 Feb 2. Exp Hematol. 2012. PMID: 22306295 Free PMC article.
Fucosylation with fucosyltransferase VI or fucosyltransferase VII improves cord blood engraftment.
Robinson SN, Thomas MW, Simmons PJ, Lu J, Yang H, Parmar S, Liu X, Shah N, Martín-Antonio B, Bollard C, Dotti G, Savoldo B, Cooper LJ, Najjar A, Rezvani K, Kaur I, McNiece IK, Champlin RE, Miller LP, Zweidler-McKay PA, Shpall EJ. Robinson SN, et al. Cytotherapy. 2014 Jan;16(1):84-9. doi: 10.1016/j.jcyt.2013.07.003. Epub 2013 Oct 1. Cytotherapy. 2014. PMID: 24094497 Free PMC article.
Expression of a surface antigen (MA6) by peripheral blood CD34+ cells is correlated with improved platelet engraftment and may explain delayed platelet engraftment following cord blood transplantation.
Simmons PJ, Robinson SN, Munsell MF, Thomas MW, Javni JA, Brouard N, Zweidler-McKay PA, Shpall EJ. Simmons PJ, et al. Stem Cells Dev. 2015 May 1;24(9):1066-72. doi: 10.1089/scd.2014.0439. Epub 2015 Mar 18. Stem Cells Dev. 2015. PMID: 25674667 Free PMC article.
Enforced fucosylation of cord blood hematopoietic cells accelerates neutrophil and platelet engraftment after transplantation.
Popat U, Mehta RS, Rezvani K, Fox P, Kondo K, Marin D, McNiece I, Oran B, Hosing C, Olson A, Parmar S, Shah N, Andreeff M, Kebriaei P, Kaur I, Yvon E, de Lima M, Cooper LJ, Tewari P, Champlin RE, Nieto Y, Andersson BS, Alousi A, Jones RB, Qazilbash MH, Bashir Q, Ciurea S, Ahmed S, Anderlini P, Bosque D, Bollard C, Molldrem JJ, Chen J, Rondon G, Thomas M, Miller L, Wolpe S, Simmons P, Robinson S, Zweidler-McKay PA, Shpall EJ. Popat U, et al. Blood. 2015 May 7;125(19):2885-92. doi: 10.1182/blood-2015-01-607366. Epub 2015 Mar 16. Blood. 2015. PMID: 25778529 Free PMC article.
93 results