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The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors.
Marrs WR, Blankman JL, Horne EA, Thomazeau A, Lin YH, Coy J, Bodor AL, Muccioli GG, Hu SS, Woodruff G, Fung S, Lafourcade M, Alexander JP, Long JZ, Li W, Xu C, Möller T, Mackie K, Manzoni OJ, Cravatt BF, Stella N. Marrs WR, et al. Among authors: blankman jl. Nat Neurosci. 2010 Aug;13(8):951-7. doi: 10.1038/nn.2601. Epub 2010 Jul 25. Nat Neurosci. 2010. PMID: 20657592 Free PMC article.
Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system.
Schlosburg JE, Blankman JL, Long JZ, Nomura DK, Pan B, Kinsey SG, Nguyen PT, Ramesh D, Booker L, Burston JJ, Thomas EA, Selley DE, Sim-Selley LJ, Liu QS, Lichtman AH, Cravatt BF. Schlosburg JE, et al. Among authors: blankman jl. Nat Neurosci. 2010 Sep;13(9):1113-9. doi: 10.1038/nn.2616. Epub 2010 Aug 22. Nat Neurosci. 2010. PMID: 20729846 Free PMC article.
Endocannabinoid overload.
Lichtman AH, Blankman JL, Cravatt BF. Lichtman AH, et al. Among authors: blankman jl. Mol Pharmacol. 2010 Dec;78(6):993-5. doi: 10.1124/mol.110.069427. Epub 2010 Oct 15. Mol Pharmacol. 2010. PMID: 20952498 Free PMC article. Review.
Chemical probes of endocannabinoid metabolism.
Blankman JL, Cravatt BF. Blankman JL, et al. Pharmacol Rev. 2013 Mar 19;65(2):849-71. doi: 10.1124/pr.112.006387. Print 2013 Apr. Pharmacol Rev. 2013. PMID: 23512546 Free PMC article. Review.
Two novel mutations in ABHD12: expansion of the mutation spectrum in PHARC and assessment of their functional effects.
Chen DH, Naydenov A, Blankman JL, Mefford HC, Davis M, Sul Y, Barloon AS, Bonkowski E, Wolff J, Matsushita M, Smith C, Cravatt BF, Mackie K, Raskind WH, Stella N, Bird TD. Chen DH, et al. Among authors: blankman jl. Hum Mutat. 2013 Dec;34(12):1672-8. doi: 10.1002/humu.22437. Epub 2013 Oct 2. Hum Mutat. 2013. PMID: 24027063 Free PMC article.
25 results