Endo S - Search Results

1

Factorizing the role of a critical leucine residue in the binding of substrate to human 20alpha-hydroxysteroid dehydrogenase (AKR1C1): molecular modeling and kinetic studies of the Leu308Val mutant enzyme.

Dhagat U, Endo S, Soda M, Hara A, El-Kabbani O. Dhagat U, et al. Among authors: endo s. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5274-6. doi: 10.1016/j.bmcl.2010.06.137. Epub 2010 Jul 1. Bioorg Med Chem Lett. 2010. PMID: 20656485

2

Enzymatic properties of a member (AKR1C20) of the aldo-keto reductase family.

Matsumoto K, Endo S, Ishikura S, Matsunaga T, Tajima K, El-Kabbani O, Hara A. Matsumoto K, et al. Among authors: endo s. Biol Pharm Bull. 2006 Mar;29(3):539-42. doi: 10.1248/bpb.29.539. Biol Pharm Bull. 2006. PMID: 16508162 Free article.

3

Substrate specificity of a mouse aldo-keto reductase (AKR1C12).

Endo S, Matsumoto K, Matsunaga T, Ishikura S, Tajima K, El-Kabbani O, Hara A. Endo S, et al. Biol Pharm Bull. 2006 Dec;29(12):2488-92. doi: 10.1248/bpb.29.2488. Biol Pharm Bull. 2006. PMID: 17142987 Free article.

4

Rat NAD+-dependent 3alpha-hydroxysteroid dehydrogenase (AKR1C17): a member of the aldo-keto reductase family highly expressed in kidney cytosol.

Sanai M, Endo S, Matsunaga T, Ishikura S, Tajima K, El-Kabbani O, Hara A. Sanai M, et al. Among authors: endo s. Arch Biochem Biophys. 2007 Aug 1;464(1):122-9. doi: 10.1016/j.abb.2007.04.003. Epub 2007 Apr 17. Arch Biochem Biophys. 2007. PMID: 17475203

5

Enzymatic characteristics of an aldo-keto reductase family protein (AKR1C15) and its localization in rat tissues.

Endo S, Matsunaga T, Horie K, Tajima K, Bunai Y, Carbone V, El-Kabbani O, Hara A. Endo S, et al. Arch Biochem Biophys. 2007 Sep 1;465(1):136-47. doi: 10.1016/j.abb.2007.05.008. Epub 2007 May 30. Arch Biochem Biophys. 2007. PMID: 17574202

6

Structures of dimeric dihydrodiol dehydrogenase apoenzyme and inhibitor complex: probing the subunit interface with site-directed mutagenesis.

Carbone V, Endo S, Sumii R, Chung RP, Matsunaga T, Hara A, El-Kabbani O. Carbone V, et al. Among authors: endo s. Proteins. 2008 Jan 1;70(1):176-87. doi: 10.1002/prot.21566. Proteins. 2008. PMID: 17654552

7

Characterization of an oligomeric carbonyl reductase of dog liver: its identity with peroxisomal tetrameric carbonyl reductase.

Endo S, Matsunaga T, Nagano M, Abe H, Ishikura S, Imamura Y, Hara A. Endo S, et al. Biol Pharm Bull. 2007 Sep;30(9):1787-91. doi: 10.1248/bpb.30.1787. Biol Pharm Bull. 2007. PMID: 17827741 Free article.

8

Characterization of rat and mouse NAD+-dependent 3alpha/17beta/20alpha-hydroxysteroid dehydrogenases and identification of substrate specificity determinants by site-directed mutagenesis.

Endo S, Sanai M, Horie K, Matsunaga T, Ishikura S, Tajima K, El-Kabbani O, Hara A. Endo S, et al. Arch Biochem Biophys. 2007 Nov 1;467(1):76-86. doi: 10.1016/j.abb.2007.08.011. Epub 2007 Aug 24. Arch Biochem Biophys. 2007. PMID: 17888864

9

Structure of 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) holoenzyme from an orthorhombic crystal form: an insight into the bifunctionality of the enzyme.

Dhagat U, Carbone V, Chung RP, Schulze-Briese C, Endo S, Hara A, El-Kabbani O. Dhagat U, et al. Among authors: endo s. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Oct 1;63(Pt 10):825-30. doi: 10.1107/S1744309107040985. Epub 2007 Sep 19. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007. PMID: 17909281 Free PMC article.

10

A salicylic acid-based analogue discovered from virtual screening as a potent inhibitor of human 20alpha-hydroxysteroid dehydrogenase.

Dhagat U, Carbone V, Chung RP, Matsunaga T, Endo S, Hara A, El-Kabbani O. Dhagat U, et al. Among authors: endo s. Med Chem. 2007 Nov;3(6):546-50. doi: 10.2174/157340607782360399. Med Chem. 2007. PMID: 18045204

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