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Down-regulation of SREBP-1c is associated with the development of burned-out NASH.
Nagaya T, Tanaka N, Suzuki T, Sano K, Horiuchi A, Komatsu M, Nakajima T, Nishizawa T, Joshita S, Umemura T, Ichijo T, Matsumoto A, Yoshizawa K, Nakayama J, Tanaka E, Aoyama T. Nagaya T, et al. Among authors: aoyama t. J Hepatol. 2010 Oct;53(4):724-31. doi: 10.1016/j.jhep.2010.04.033. Epub 2010 Jul 1. J Hepatol. 2010. PMID: 20655124
Steatogenesis in adult-onset type II citrullinemia is associated with down-regulation of PPARα.
Komatsu M, Kimura T, Yazaki M, Tanaka N, Yang Y, Nakajima T, Horiuchi A, Fang ZZ, Joshita S, Matsumoto A, Umemura T, Tanaka E, Gonzalez FJ, Ikeda S, Aoyama T. Komatsu M, et al. Among authors: aoyama t. Biochim Biophys Acta. 2015 Mar;1852(3):473-81. doi: 10.1016/j.bbadis.2014.12.011. Epub 2014 Dec 20. Biochim Biophys Acta. 2015. PMID: 25533124 Free PMC article.
[PPAR and NASH].
Tanaka N, Aoyama T. Tanaka N, et al. Among authors: aoyama t. Nihon Rinsho. 2006 Jun;64(6):1089-94. Nihon Rinsho. 2006. PMID: 16768114 Review. Japanese.
Insulin resistance and hepatitis C virus: a case-control study of non-obese, non-alcoholic and non-steatotic hepatitis virus carriers with persistently normal serum aminotransferase.
Tanaka N, Nagaya T, Komatsu M, Horiuchi A, Tsuruta G, Shirakawa H, Umemura T, Ichijo T, Matsumoto A, Yoshizawa K, Aoyama T, Kiyosawa K, Tanaka E. Tanaka N, et al. Among authors: aoyama t. Liver Int. 2008 Sep;28(8):1104-11. doi: 10.1111/j.1478-3231.2008.01737.x. Epub 2008 Apr 7. Liver Int. 2008. PMID: 18397231
Bezafibrate at clinically relevant doses decreases serum/liver triglycerides via down-regulation of sterol regulatory element-binding protein-1c in mice: a novel peroxisome proliferator-activated receptor alpha-independent mechanism.
Nakajima T, Tanaka N, Kanbe H, Hara A, Kamijo Y, Zhang X, Gonzalez FJ, Aoyama T. Nakajima T, et al. Among authors: aoyama t. Mol Pharmacol. 2009 Apr;75(4):782-92. doi: 10.1124/mol.108.052928. Epub 2009 Jan 5. Mol Pharmacol. 2009. PMID: 19124612 Free PMC article.
2,348 results