Chang WL - Search Results

1

2-Phenyl-5-(pyrrolidin-1-yl)-1-(3,4,5-trimethoxybenzyl)-1H-benzimidazole, a benzimidazole derivative, inhibits growth of human prostate cancer cells by affecting tubulin and c-Jun N-terminal kinase.

Chang WL, Chang CS, Chiang PC, Ho YF, Liu JF, Chang KW, Guh JH. Chang WL, et al. Among authors: chang cs, chang kw. Br J Pharmacol. 2010 Aug;160(7):1677-89. doi: 10.1111/j.1476-5381.2010.00832.x. Br J Pharmacol. 2010. PMID: 20649571 Free PMC article.

2

Mana-Hox displays anticancer activity against prostate cancer cells through tubulin depolymerization and DNA damage stress.

Hsiao CJ, Ho YF, Hsu JT, Chang WL, Chen YC, Shen YC, Lyu PC, Guh JH. Hsiao CJ, et al. Among authors: chang wl. Naunyn Schmiedebergs Arch Pharmacol. 2008 Dec;378(6):599-608. doi: 10.1007/s00210-008-0330-7. Epub 2008 Jul 29. Naunyn Schmiedebergs Arch Pharmacol. 2008. PMID: 18663430

3

Development of novel adenosine monophosphate-activated protein kinase activators.

Guh JH, Chang WL, Yang J, Lee SL, Wei S, Wang D, Kulp SK, Chen CS. Guh JH, et al. Among authors: chang wl. J Med Chem. 2010 Mar 25;53(6):2552-61. doi: 10.1021/jm901773d. J Med Chem. 2010. Retraction in: J Med Chem. 2018 Jun 14;61(11):5055. doi: 10.1021/acs.jmedchem.8b00707 PMID: 20170185 Free PMC article. Retracted.

4

Tubulin-binding agents down-regulate matrix metalloproteinase-2 and -9 in human hormone-refractory prostate cancer cells – a critical role of Cdk1 in mitotic entry.

Chang WL, Yu CC, Chen CS, Guh JH. Chang WL, et al. Biochem Pharmacol. 2015 Mar 1;94(1):12-21. doi: 10.1016/j.bcp.2015.01.005. Epub 2015 Jan 20. Biochem Pharmacol. 2015. PMID: 25615907

5

Epi-reevesioside F inhibits Na+/K+-ATPase, causing cytosolic acidification, Bak activation and apoptosis in glioblastoma.

Hsu JL, Liu FL, Hsu LC, Chang HS, Leu WJ, Yu CC, Chang WL, Chen IS, Kung FL, Guh JH. Hsu JL, et al. Among authors: chang hs, chang wl. Oncotarget. 2015 Sep 15;6(27):24032-46. doi: 10.18632/oncotarget.4429. Oncotarget. 2015. PMID: 26125228 Free PMC article.

6

Repurposing of phentolamine as a potential anticancer agent against human castration-resistant prostate cancer: A central role on microtubule stabilization and mitochondrial apoptosis pathway.

Ho CH, Hsu JL, Liu SP, Hsu LC, Chang WL, Chao CC, Guh JH. Ho CH, et al. Among authors: chang wl. Prostate. 2015 Sep;75(13):1454-66. doi: 10.1002/pros.23033. Epub 2015 Jul 14. Prostate. 2015. PMID: 26180030

7

Zerumbone, a ginger sesquiterpene, induces apoptosis and autophagy in human hormone-refractory prostate cancers through tubulin binding and crosstalk between endoplasmic reticulum stress and mitochondrial insult.

Chan ML, Liang JW, Hsu LC, Chang WL, Lee SS, Guh JH. Chan ML, et al. Among authors: chang wl. Naunyn Schmiedebergs Arch Pharmacol. 2015 Nov;388(11):1223-36. doi: 10.1007/s00210-015-1152-z. Epub 2015 Aug 6. Naunyn Schmiedebergs Arch Pharmacol. 2015. PMID: 26246051

8

Repurposing of nitroxoline as a potential anticancer agent against human prostate cancer: a crucial role on AMPK/mTOR signaling pathway and the interplay with Chk2 activation.

Chang WL, Hsu LC, Leu WJ, Chen CS, Guh JH. Chang WL, et al. Oncotarget. 2015 Nov 24;6(37):39806-20. doi: 10.18632/oncotarget.5655. Oncotarget. 2015. PMID: 26447757 Free PMC article.

9

Non-immunosuppressive triazole-based small molecule induces anticancer activity against human hormone-refractory prostate cancers: the role in inhibition of PI3K/AKT/mTOR and c-Myc signaling pathways.

Leu WJ, Swain ShP, Chan SH, Hsu JL, Liu SP, Chan ML, Yu CC, Hsu LC, Chou YL, Chang WL, Hou DR, Guh JH. Leu WJ, et al. Among authors: chang wl. Oncotarget. 2016 Nov 22;7(47):76995-77009. doi: 10.18632/oncotarget.12765. Oncotarget. 2016. PMID: 27769069 Free PMC article.

10

Retraction of "Development of Novel Adenosine Monophosphate-Activated Protein Kinase Activators".

Guh JH, Chang WL, Yang J, Lee SL, Wei S, Wang D, Kulp SK, Chen CS. Guh JH, et al. Among authors: chang wl. J Med Chem. 2018 Jun 14;61(11):5055. doi: 10.1021/acs.jmedchem.8b00707. Epub 2018 May 18. J Med Chem. 2018. PMID: 29772897 Free PMC article. No abstract available.

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