Ajikumar PK - Search Results

1

Combining metabolic and protein engineering of a terpenoid biosynthetic pathway for overproduction and selectivity control.

Leonard E, Ajikumar PK, Thayer K, Xiao WH, Mo JD, Tidor B, Stephanopoulos G, Prather KL. Leonard E, et al. Among authors: ajikumar pk. Proc Natl Acad Sci U S A. 2010 Aug 3;107(31):13654-9. doi: 10.1073/pnas.1006138107. Epub 2010 Jul 19. Proc Natl Acad Sci U S A. 2010. PMID: 20643967 Free PMC article.

2

Isoprenoid pathway optimization for Taxol precursor overproduction in Escherichia coli.

Ajikumar PK, Xiao WH, Tyo KE, Wang Y, Simeon F, Leonard E, Mucha O, Phon TH, Pfeifer B, Stephanopoulos G. Ajikumar PK, et al. Science. 2010 Oct 1;330(6000):70-4. doi: 10.1126/science.1191652. Science. 2010. PMID: 20929806 Free PMC article.

3

Engineering microbial cell factories for biosynthesis of isoprenoid molecules: beyond lycopene.

Klein-Marcuschamer D, Ajikumar PK, Stephanopoulos G. Klein-Marcuschamer D, et al. Among authors: ajikumar pk. Trends Biotechnol. 2007 Sep;25(9):417-24. doi: 10.1016/j.tibtech.2007.07.006. Epub 2007 Aug 2. Trends Biotechnol. 2007. PMID: 17681626 Review.

4

Stabilized gene duplication enables long-term selection-free heterologous pathway expression.

Tyo KE, Ajikumar PK, Stephanopoulos G. Tyo KE, et al. Among authors: ajikumar pk. Nat Biotechnol. 2009 Aug;27(8):760-5. doi: 10.1038/nbt.1555. Epub 2009 Jul 26. Nat Biotechnol. 2009. PMID: 19633654

5

Analysis of heterologous taxadiene production in K- and B-derived Escherichia coli.

Boghigian BA, Salas D, Ajikumar PK, Stephanopoulos G, Pfeifer BA. Boghigian BA, et al. Among authors: ajikumar pk. Appl Microbiol Biotechnol. 2012 Feb;93(4):1651-61. doi: 10.1007/s00253-011-3528-4. Epub 2011 Aug 18. Appl Microbiol Biotechnol. 2012. PMID: 21850432 Free PMC article.

6

The future of metabolic engineering and synthetic biology: towards a systematic practice.

Yadav VG, De Mey M, Lim CG, Ajikumar PK, Stephanopoulos G. Yadav VG, et al. Among authors: ajikumar pk. Metab Eng. 2012 May;14(3):233-41. doi: 10.1016/j.ymben.2012.02.001. Metab Eng. 2012. PMID: 22629571 Free PMC article. Review.

7

Overcoming heterologous protein interdependency to optimize P450-mediated Taxol precursor synthesis in Escherichia coli.

Biggs BW, Lim CG, Sagliani K, Shankar S, Stephanopoulos G, De Mey M, Ajikumar PK. Biggs BW, et al. Among authors: ajikumar pk. Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3209-14. doi: 10.1073/pnas.1515826113. Epub 2016 Mar 7. Proc Natl Acad Sci U S A. 2016. PMID: 26951651 Free PMC article.

8

Terpenoids: opportunities for biosynthesis of natural product drugs using engineered microorganisms.

Ajikumar PK, Tyo K, Carlsen S, Mucha O, Phon TH, Stephanopoulos G. Ajikumar PK, et al. Mol Pharm. 2008 Mar-Apr;5(2):167-90. doi: 10.1021/mp700151b. Epub 2008 Mar 21. Mol Pharm. 2008. PMID: 18355030 Review.

9

Enabling commercial success of industrial biotechnology.

Biggs BW, Alper HS, Pfleger BF, Tyo KEJ, Santos CNS, Ajikumar PK, Stephanopoulos G. Biggs BW, et al. Among authors: ajikumar pk. Science. 2021 Dec 24;374(6575):1563-1565. doi: 10.1126/science.abj5040. Epub 2021 Dec 23. Science. 2021. PMID: 34941395

10

Profiling RNA polymerase-promoter interaction by using ssDNA-dsDNA probe on a surface addressable microarray.

Ng JK, Ajikumar PK, Stephanopoulos G, Too HP. Ng JK, et al. Among authors: ajikumar pk. Chembiochem. 2007 Sep 24;8(14):1667-70. doi: 10.1002/cbic.200700340. Chembiochem. 2007. PMID: 17705343 No abstract available.

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