Sepp-Lorenzino L - Search Results

1

Noninvasive imaging of lipid nanoparticle-mediated systemic delivery of small-interfering RNA to the liver.

Tao W, Davide JP, Cai M, Zhang GJ, South VJ, Matter A, Ng B, Zhang Y, Sepp-Lorenzino L. Tao W, et al. Mol Ther. 2010 Sep;18(9):1657-66. doi: 10.1038/mt.2010.147. Epub 2010 Jul 13. Mol Ther. 2010. PMID: 20628357 Free PMC article.

2

Evaluation of efficacy, biodistribution, and inflammation for a potent siRNA nanoparticle: effect of dexamethasone co-treatment.

Abrams MT, Koser ML, Seitzer J, Williams SC, DiPietro MA, Wang W, Shaw AW, Mao X, Jadhav V, Davide JP, Burke PA, Sachs AB, Stirdivant SM, Sepp-Lorenzino L. Abrams MT, et al. Mol Ther. 2010 Jan;18(1):171-80. doi: 10.1038/mt.2009.208. Epub 2009 Sep 8. Mol Ther. 2010. PMID: 19738601 Free PMC article.

3

Mechanistically probing lipid-siRNA nanoparticle-associated toxicities identifies Jak inhibitors effective in mitigating multifaceted toxic responses.

Tao W, Mao X, Davide JP, Ng B, Cai M, Burke PA, Sachs AB, Sepp-Lorenzino L. Tao W, et al. Mol Ther. 2011 Mar;19(3):567-75. doi: 10.1038/mt.2010.282. Epub 2010 Dec 21. Mol Ther. 2011. PMID: 21179008 Free PMC article.

4

Biodistribution of small interfering RNA at the organ and cellular levels after lipid nanoparticle-mediated delivery.

Shi B, Keough E, Matter A, Leander K, Young S, Carlini E, Sachs AB, Tao W, Abrams M, Howell B, Sepp-Lorenzino L. Shi B, et al. J Histochem Cytochem. 2011 Aug;59(8):727-40. doi: 10.1369/0022155411410885. J Histochem Cytochem. 2011. PMID: 21804077 Free PMC article.

5

An inhibitor of the kinesin spindle protein activates the intrinsic apoptotic pathway independently of p53 and de novo protein synthesis.

Tao W, South VJ, Diehl RE, Davide JP, Sepp-Lorenzino L, Fraley ME, Arrington KL, Lobell RB. Tao W, et al. Mol Cell Biol. 2007 Jan;27(2):689-98. doi: 10.1128/MCB.01505-06. Epub 2006 Nov 13. Mol Cell Biol. 2007. PMID: 17101792 Free PMC article.

6

Systematic chemical modifications of single stranded siRNAs significantly improved CTNNB1 mRNA silencing.

Chang W, Pei Y, Guidry EN, Zewge D, Parish CA, Sherer EC, DiMuzio J, Zhang H, South VJ, Strapps WR, Sepp-Lorenzino L, Colletti SL, Stanton MG. Chang W, et al. Bioorg Med Chem Lett. 2016 Sep 15;26(18):4513-4517. doi: 10.1016/j.bmcl.2016.07.064. Epub 2016 Jul 28. Bioorg Med Chem Lett. 2016. PMID: 27503684

7

Intratracheal Administration of siRNA Triggers mRNA Silencing in the Lung to Modulate T Cell Immune Response and Lung Inflammation.

Ng B, Cash-Mason T, Wang Y, Seitzer J, Burchard J, Brown D, Dudkin V, Davide J, Jadhav V, Sepp-Lorenzino L, Cejas PJ. Ng B, et al. Among authors: sepp lorenzino l. Mol Ther Nucleic Acids. 2019 Jun 7;16:194-205. doi: 10.1016/j.omtn.2019.02.013. Epub 2019 Feb 26. Mol Ther Nucleic Acids. 2019. PMID: 30901578 Free PMC article.

8

Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage.

Tao W, South VJ, Zhang Y, Davide JP, Farrell L, Kohl NE, Sepp-Lorenzino L, Lobell RB. Tao W, et al. Cancer Cell. 2005 Jul;8(1):49-59. doi: 10.1016/j.ccr.2005.06.003. Cancer Cell. 2005. PMID: 16023598 Free article.

9

Quantification of Cy-5 siRNA signal in the intra-vital multi-photon microscopy images.

Chen A, Dogdas B, Mehta S, Haskell K, Ng B, Keough E, Howell B, Meacham DA, Aslamkhan AG, Davide J, Stanton M, Bagchi A, Sepp-Lorenzino L, Tao W. Chen A, et al. Annu Int Conf IEEE Eng Med Biol Soc. 2012;2012:3712-5. doi: 10.1109/EMBC.2012.6346773. Annu Int Conf IEEE Eng Med Biol Soc. 2012. PMID: 23366734

10

Silencing Myostatin Using Cholesterol-conjugated siRNAs Induces Muscle Growth.

Khan T, Weber H, DiMuzio J, Matter A, Dogdas B, Shah T, Thankappan A, Disa J, Jadhav V, Lubbers L, Sepp-Lorenzino L, Strapps WR, Tadin-Strapps M. Khan T, et al. Mol Ther Nucleic Acids. 2016 Aug 2;5(8):e342. doi: 10.1038/mtna.2016.55. Mol Ther Nucleic Acids. 2016. PMID: 27483025 Free PMC article.

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