Davide JP - Search Results

1

Noninvasive imaging of lipid nanoparticle-mediated systemic delivery of small-interfering RNA to the liver.

Tao W, Davide JP, Cai M, Zhang GJ, South VJ, Matter A, Ng B, Zhang Y, Sepp-Lorenzino L. Tao W, et al. Among authors: davide jp. Mol Ther. 2010 Sep;18(9):1657-66. doi: 10.1038/mt.2010.147. Epub 2010 Jul 13. Mol Ther. 2010. PMID: 20628357 Free PMC article.

2

Evaluation of efficacy, biodistribution, and inflammation for a potent siRNA nanoparticle: effect of dexamethasone co-treatment.

Abrams MT, Koser ML, Seitzer J, Williams SC, DiPietro MA, Wang W, Shaw AW, Mao X, Jadhav V, Davide JP, Burke PA, Sachs AB, Stirdivant SM, Sepp-Lorenzino L. Abrams MT, et al. Among authors: davide jp. Mol Ther. 2010 Jan;18(1):171-80. doi: 10.1038/mt.2009.208. Epub 2009 Sep 8. Mol Ther. 2010. PMID: 19738601 Free PMC article.

3

Mechanistically probing lipid-siRNA nanoparticle-associated toxicities identifies Jak inhibitors effective in mitigating multifaceted toxic responses.

Tao W, Mao X, Davide JP, Ng B, Cai M, Burke PA, Sachs AB, Sepp-Lorenzino L. Tao W, et al. Among authors: davide jp. Mol Ther. 2011 Mar;19(3):567-75. doi: 10.1038/mt.2010.282. Epub 2010 Dec 21. Mol Ther. 2011. PMID: 21179008 Free PMC article.

4

Intratracheal Administration of siRNA Triggers mRNA Silencing in the Lung to Modulate T Cell Immune Response and Lung Inflammation.

Ng B, Cash-Mason T, Wang Y, Seitzer J, Burchard J, Brown D, Dudkin V, Davide J, Jadhav V, Sepp-Lorenzino L, Cejas PJ. Ng B, et al. Mol Ther Nucleic Acids. 2019 Jun 7;16:194-205. doi: 10.1016/j.omtn.2019.02.013. Epub 2019 Feb 26. Mol Ther Nucleic Acids. 2019. PMID: 30901578 Free PMC article.

5

An inhibitor of the kinesin spindle protein activates the intrinsic apoptotic pathway independently of p53 and de novo protein synthesis.

Tao W, South VJ, Diehl RE, Davide JP, Sepp-Lorenzino L, Fraley ME, Arrington KL, Lobell RB. Tao W, et al. Among authors: davide jp. Mol Cell Biol. 2007 Jan;27(2):689-98. doi: 10.1128/MCB.01505-06. Epub 2006 Nov 13. Mol Cell Biol. 2007. PMID: 17101792 Free PMC article.

6

Quantification of Cy-5 siRNA signal in the intra-vital multi-photon microscopy images.

Chen A, Dogdas B, Mehta S, Haskell K, Ng B, Keough E, Howell B, Meacham DA, Aslamkhan AG, Davide J, Stanton M, Bagchi A, Sepp-Lorenzino L, Tao W. Chen A, et al. Annu Int Conf IEEE Eng Med Biol Soc. 2012;2012:3712-5. doi: 10.1109/EMBC.2012.6346773. Annu Int Conf IEEE Eng Med Biol Soc. 2012. PMID: 23366734

7

Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage.

Tao W, South VJ, Zhang Y, Davide JP, Farrell L, Kohl NE, Sepp-Lorenzino L, Lobell RB. Tao W, et al. Among authors: davide jp. Cancer Cell. 2005 Jul;8(1):49-59. doi: 10.1016/j.ccr.2005.06.003. Cancer Cell. 2005. PMID: 16023598 Free article.

8

Visualization of mitotic arrest of cell cycle with bioluminescence imaging in living animals.

Zhang GJ, Chen TB, Davide J, Tao W, Vanko A, Connolly B, Williams DL Jr, Sur C. Zhang GJ, et al. Mol Imaging Biol. 2013 Aug;15(4):431-40. doi: 10.1007/s11307-013-0619-x. Mol Imaging Biol. 2013. PMID: 23440602 Free PMC article.

9

Kinesin spindle protein (KSP) inhibitors. Part 7: Design and synthesis of 3,3-disubstituted dihydropyrazolobenzoxazines as potent inhibitors of the mitotic kinesin KSP.

Garbaccio RM, Tasber ES, Neilson LA, Coleman PJ, Fraley ME, Olson C, Bergman J, Torrent M, Buser CA, Rickert K, Walsh ES, Hamilton K, Lobell RB, Tao W, South VJ, Diehl RE, Davide JP, Yan Y, Kuo LC, Li C, Prueksaritanont T, Fernandez-Metzler C, Mahan EA, Slaughter DE, Salata JJ, Kohl NE, Huber HE, Hartman GD. Garbaccio RM, et al. Among authors: davide jp. Bioorg Med Chem Lett. 2007 Oct 15;17(20):5671-6. doi: 10.1016/j.bmcl.2007.07.067. Epub 2007 Aug 21. Bioorg Med Chem Lett. 2007. PMID: 17804233

10

Kinesin spindle protein (KSP) inhibitors. 9. Discovery of (2S)-4-(2,5-difluorophenyl)-n-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide (MK-0731) for the treatment of taxane-refractory cancer.

Cox CD, Coleman PJ, Breslin MJ, Whitman DB, Garbaccio RM, Fraley ME, Buser CA, Walsh ES, Hamilton K, Schaber MD, Lobell RB, Tao W, Davide JP, Diehl RE, Abrams MT, South VJ, Huber HE, Torrent M, Prueksaritanont T, Li C, Slaughter DE, Mahan E, Fernandez-Metzler C, Yan Y, Kuo LC, Kohl NE, Hartman GD. Cox CD, et al. Among authors: davide jp. J Med Chem. 2008 Jul 24;51(14):4239-52. doi: 10.1021/jm800386y. Epub 2008 Jun 25. J Med Chem. 2008. PMID: 18578472

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