Watkins H - Search Results

1

Normal passive viscoelasticity but abnormal myofibrillar force generation in human hypertrophic cardiomyopathy.

Hoskins AC, Jacques A, Bardswell SC, McKenna WJ, Tsang V, dos Remedios CG, Ehler E, Adams K, Jalilzadeh S, Avkiran M, Watkins H, Redwood C, Marston SB, Kentish JC. Hoskins AC, et al. Among authors: watkins h. J Mol Cell Cardiol. 2010 Nov;49(5):737-45. doi: 10.1016/j.yjmcc.2010.06.006. Epub 2010 Jul 6. J Mol Cell Cardiol. 2010. PMID: 20615414 Free PMC article.

2

Two mutations in troponin I that cause hypertrophic cardiomyopathy have contrasting effects on cardiac muscle contractility.

Burton D, Abdulrazzak H, Knott A, Elliott K, Redwood C, Watkins H, Marston S, Ashley C. Burton D, et al. Among authors: watkins h. Biochem J. 2002 Mar 1;362(Pt 2):443-51. doi: 10.1042/0264-6021:3620443. Biochem J. 2002. PMID: 11853553 Free PMC article.

3

Mutations of the light meromyosin domain of the beta-myosin heavy chain rod in hypertrophic cardiomyopathy.

Blair E, Redwood C, de Jesus Oliveira M, Moolman-Smook JC, Brink P, Corfield VA, Ostman-Smith I, Watkins H. Blair E, et al. Among authors: watkins h. Circ Res. 2002 Feb 22;90(3):263-9. doi: 10.1161/hh0302.104532. Circ Res. 2002. PMID: 11861413

4

Alterations in thin filament regulation induced by a human cardiac troponin T mutant that causes dilated cardiomyopathy are distinct from those induced by troponin T mutants that cause hypertrophic cardiomyopathy.

Robinson P, Mirza M, Knott A, Abdulrazzak H, Willott R, Marston S, Watkins H, Redwood C. Robinson P, et al. Among authors: watkins h. J Biol Chem. 2002 Oct 25;277(43):40710-6. doi: 10.1074/jbc.M203446200. Epub 2002 Aug 18. J Biol Chem. 2002. PMID: 12186860 Free article.

5

Identification of novel interactions between domains of Myosin binding protein-C that are modulated by hypertrophic cardiomyopathy missense mutations.

Moolman-Smook J, Flashman E, de Lange W, Li Z, Corfield V, Redwood C, Watkins H. Moolman-Smook J, et al. Among authors: watkins h. Circ Res. 2002 Oct 18;91(8):704-11. doi: 10.1161/01.res.0000036750.81083.83. Circ Res. 2002. PMID: 12386147

6

Hypertrophic cardiomyopathy:a paradigm for myocardial energy depletion.

Ashrafian H, Redwood C, Blair E, Watkins H. Ashrafian H, et al. Among authors: watkins h. Trends Genet. 2003 May;19(5):263-8. doi: 10.1016/S0168-9525(03)00081-7. Trends Genet. 2003. PMID: 12711218 Review.

7

Hypertrophic cardiomyopathy due to sarcomeric gene mutations is characterized by impaired energy metabolism irrespective of the degree of hypertrophy.

Crilley JG, Boehm EA, Blair E, Rajagopalan B, Blamire AM, Styles P, McKenna WJ, Ostman-Smith I, Clarke K, Watkins H. Crilley JG, et al. Among authors: watkins h. J Am Coll Cardiol. 2003 May 21;41(10):1776-82. doi: 10.1016/s0735-1097(02)03009-7. J Am Coll Cardiol. 2003. PMID: 12767664 Free article.

8

Ascertainment strategies and genotype:phenotype correlations in hypertrophic cardiomyopathy.

Blair E, Redwood C, Watkins H. Blair E, et al. Among authors: watkins h. Circulation. 2003 Jul 29;108(4):e24-5; author reply e24-5. doi: 10.1161/01.CIR.0000081440.49766.A6. Circulation. 2003. PMID: 12885737 No abstract available.

9

Mutation analysis of AMP-activated protein kinase subunits in inherited cardiomyopathies: implications for kinase function and disease pathogenesis.

Oliveira SM, Ehtisham J, Redwood CS, Ostman-Smith I, Blair EM, Watkins H. Oliveira SM, et al. Among authors: watkins h. J Mol Cell Cardiol. 2003 Oct;35(10):1251-5. doi: 10.1016/s0022-2828(03)00237-2. J Mol Cell Cardiol. 2003. PMID: 14519435

10

Cardiac myosin binding protein C: its role in physiology and disease.

Flashman E, Redwood C, Moolman-Smook J, Watkins H. Flashman E, et al. Among authors: watkins h. Circ Res. 2004 May 28;94(10):1279-89. doi: 10.1161/01.RES.0000127175.21818.C2. Circ Res. 2004. PMID: 15166115 Review.

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