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Page 1
Decoy oligodeoxyribonucleotides and peptide nucleic acids-DNA chimeras targeting nuclear factor kappa-B: inhibition of IL-8 gene expression in cystic fibrosis cells infected with Pseudomonas aeruginosa.
Gambari R, Borgatti M, Bezzerri V, Nicolis E, Lampronti I, Dechecchi MC, Mancini I, Tamanini A, Cabrini G. Gambari R, et al. Among authors: mancini i. Biochem Pharmacol. 2010 Dec 15;80(12):1887-94. doi: 10.1016/j.bcp.2010.06.047. Epub 2010 Jul 6. Biochem Pharmacol. 2010. PMID: 20615393 Review.
Targeting transcription factor activity as a strategy to inhibit pro-inflammatory genes involved in cystic fibrosis: decoy oligonucleotides and low-molecular weight compounds.
Cabrini G, Bezzerri V, Mancini I, Nicolis E, Dechecchi MC, Tamanini A, Lampronti I, Piccagli L, Bianchi N, Borgatti M, Gambari R. Cabrini G, et al. Among authors: mancini i. Curr Med Chem. 2010;17(35):4392-404. doi: 10.2174/092986710793361243. Curr Med Chem. 2010. PMID: 20939807 Review.
Induction of IL-6 gene expression in a CF bronchial epithelial cell line by Pseudomonas aeruginosa is dependent on transcription factors belonging to the Sp1 superfamily.
Borgatti M, Bezzerri V, Mancini I, Nicolis E, Dechecchi MC, Lampronti I, Rizzotti P, Cabrini G, Gambari R. Borgatti M, et al. Among authors: mancini i. Biochem Biophys Res Commun. 2007 Jun 15;357(4):977-83. doi: 10.1016/j.bbrc.2007.04.081. Epub 2007 Apr 20. Biochem Biophys Res Commun. 2007. PMID: 17466942
Docking of molecules identified in bioactive medicinal plants extracts into the p50 NF-kappaB transcription factor: correlation with inhibition of NF-kappaB/DNA interactions and inhibitory effects on IL-8 gene expression.
Piccagli L, Fabbri E, Borgatti M, Bezzerri V, Mancini I, Nicolis E, Dechecchi MC, Lampronti I, Cabrini G, Gambari R. Piccagli L, et al. Among authors: mancini i. BMC Struct Biol. 2008 Sep 3;8:38. doi: 10.1186/1472-6807-8-38. BMC Struct Biol. 2008. PMID: 18768082 Free PMC article.
Modulation of expression of IL-8 gene in bronchial epithelial cells by 5-methoxypsoralen.
Nicolis E, Lampronti I, Dechecchi MC, Borgatti M, Tamanini A, Bezzerri V, Bianchi N, Mazzon M, Mancini I, Giri MG, Rizzotti P, Gambari R, Cabrini G. Nicolis E, et al. Among authors: mancini i. Int Immunopharmacol. 2009 Nov;9(12):1411-22. doi: 10.1016/j.intimp.2009.08.013. Epub 2009 Aug 29. Int Immunopharmacol. 2009. PMID: 19720161
Virtual screening against nuclear factor κB (NF-κB) of a focus library: Identification of bioactive furocoumarin derivatives inhibiting NF-κB dependent biological functions involved in cystic fibrosis.
Piccagli L, Borgatti M, Nicolis E, Bianchi N, Mancini I, Lampronti I, Vevaldi D, Dall'Acqua F, Cabrini G, Gambari R. Piccagli L, et al. Among authors: mancini i. Bioorg Med Chem. 2010 Dec 1;18(23):8341-9. doi: 10.1016/j.bmc.2010.09.063. Epub 2010 Oct 1. Bioorg Med Chem. 2010. PMID: 20980154
Effects of decoy molecules targeting NF-kappaB transcription factors in Cystic fibrosis IB3-1 cells: recruitment of NF-kappaB to the IL-8 gene promoter and transcription of the IL-8 gene.
Finotti A, Borgatti M, Bezzerri V, Nicolis E, Lampronti I, Dechecchi M, Mancini I, Cabrini G, Saviano M, Avitabile C, Romanelli A, Gambari R. Finotti A, et al. Among authors: mancini i. Artif DNA PNA XNA. 2012 Apr-Jun;3(2):97-296. doi: 10.4161/adna.21061. Epub 2012 Apr 1. Artif DNA PNA XNA. 2012. PMID: 22772035 Free PMC article.
278 results