Gray NS - Search Results

1

A type-II kinase inhibitor capable of inhibiting the T315I "gatekeeper" mutant of Bcr-Abl.

Choi HG, Ren P, Adrian F, Sun F, Lee HS, Wang X, Ding Q, Zhang G, Xie Y, Zhang J, Liu Y, Tuntland T, Warmuth M, Manley PW, Mestan J, Gray NS, Sim T. Choi HG, et al. Among authors: gray ns. J Med Chem. 2010 Aug 12;53(15):5439-48. doi: 10.1021/jm901808w. J Med Chem. 2010. PMID: 20604564 Free PMC article.

2

A concise and traceless linker strategy toward combinatorial libraries of 2,6,9-substituted purines.

Ding S, Gray NS, Ding Q, Schultz PG. Ding S, et al. Among authors: gray ns. J Org Chem. 2001 Nov 30;66(24):8273-6. doi: 10.1021/jo016010f. J Org Chem. 2001. PMID: 11722241 No abstract available.

3

A combinatorial scaffold approach toward kinase-directed heterocycle libraries.

Ding S, Gray NS, Wu X, Ding Q, Schultz PG. Ding S, et al. Among authors: gray ns. J Am Chem Soc. 2002 Feb 27;124(8):1594-6. doi: 10.1021/ja0170302. J Am Chem Soc. 2002. PMID: 11853431

4

Resin-capture and release strategy toward combinatorial libraries of 2,6,9-substituted purines.

Ding S, Gray NS, Ding Q, Wu X, Schultz PG. Ding S, et al. Among authors: gray ns. J Comb Chem. 2002 Mar-Apr;4(2):183-6. doi: 10.1021/cc010080i. J Comb Chem. 2002. PMID: 11886295

5

A small molecule with osteogenesis-inducing activity in multipotent mesenchymal progenitor cells.

Wu X, Ding S, Ding Q, Gray NS, Schultz PG. Wu X, et al. Among authors: gray ns. J Am Chem Soc. 2002 Dec 11;124(49):14520-1. doi: 10.1021/ja0283908. J Am Chem Soc. 2002. PMID: 12465946

6

Small molecules that induce cardiomyogenesis in embryonic stem cells.

Wu X, Ding S, Ding Q, Gray NS, Schultz PG. Wu X, et al. Among authors: gray ns. J Am Chem Soc. 2004 Feb 18;126(6):1590-1. doi: 10.1021/ja038950i. J Am Chem Soc. 2004. PMID: 14871063

7

Synthesis and target identification of hymenialdisine analogs.

Wan Y, Hur W, Cho CY, Liu Y, Adrian FJ, Lozach O, Bach S, Mayer T, Fabbro D, Meijer L, Gray NS. Wan Y, et al. Among authors: gray ns. Chem Biol. 2004 Feb;11(2):247-59. doi: 10.1016/j.chembiol.2004.01.015. Chem Biol. 2004. PMID: 15123286

8

A genome-wide overexpression screen in yeast for small-molecule target identification.

Luesch H, Wu TY, Ren P, Gray NS, Schultz PG, Supek F. Luesch H, et al. Among authors: gray ns. Chem Biol. 2005 Jan;12(1):55-63. doi: 10.1016/j.chembiol.2004.10.015. Chem Biol. 2005. PMID: 15664515

9

Allosteric inhibitors of Bcr-abl-dependent cell proliferation.

Adrián FJ, Ding Q, Sim T, Velentza A, Sloan C, Liu Y, Zhang G, Hur W, Ding S, Manley P, Mestan J, Fabbro D, Gray NS. Adrián FJ, et al. Among authors: gray ns. Nat Chem Biol. 2006 Feb;2(2):95-102. doi: 10.1038/nchembio760. Epub 2006 Jan 15. Nat Chem Biol. 2006. PMID: 16415863

10

Rational design of inhibitors that bind to inactive kinase conformations.

Liu Y, Gray NS. Liu Y, et al. Among authors: gray ns. Nat Chem Biol. 2006 Jul;2(7):358-64. doi: 10.1038/nchembio799. Nat Chem Biol. 2006. PMID: 16783341

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