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Page 1
Metabolic networks of longevity.
Houtkooper RH, Williams RW, Auwerx J. Houtkooper RH, et al. Among authors: williams rw. Cell. 2010 Jul 9;142(1):9-14. doi: 10.1016/j.cell.2010.06.029. Cell. 2010. PMID: 20603007 Free PMC article.
Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics.
Koutnikova H, Laakso M, Lu L, Combe R, Paananen J, Kuulasmaa T, Kuusisto J, Häring HU, Hansen T, Pedersen O, Smith U, Hanefeld M, Williams RW, Auwerx J. Koutnikova H, et al. Among authors: williams rw. PLoS Genet. 2009 Aug;5(8):e1000591. doi: 10.1371/journal.pgen.1000591. Epub 2009 Aug 7. PLoS Genet. 2009. PMID: 19662162 Free PMC article.
Murine gut microbiota is defined by host genetics and modulates variation of metabolic traits.
McKnite AM, Perez-Munoz ME, Lu L, Williams EG, Brewer S, Andreux PA, Bastiaansen JW, Wang X, Kachman SD, Auwerx J, Williams RW, Benson AK, Peterson DA, Ciobanu DC. McKnite AM, et al. Among authors: williams rw, williams eg. PLoS One. 2012;7(6):e39191. doi: 10.1371/journal.pone.0039191. Epub 2012 Jun 18. PLoS One. 2012. PMID: 22723961 Free PMC article.
Mitonuclear protein imbalance as a conserved longevity mechanism.
Houtkooper RH, Mouchiroud L, Ryu D, Moullan N, Katsyuba E, Knott G, Williams RW, Auwerx J. Houtkooper RH, et al. Among authors: williams rw. Nature. 2013 May 23;497(7450):451-7. doi: 10.1038/nature12188. Nature. 2013. PMID: 23698443 Free PMC article.
Joint mouse-human phenome-wide association to test gene function and disease risk.
Wang X, Pandey AK, Mulligan MK, Williams EG, Mozhui K, Li Z, Jovaisaite V, Quarles LD, Xiao Z, Huang J, Capra JA, Chen Z, Taylor WL, Bastarache L, Niu X, Pollard KS, Ciobanu DC, Reznik AO, Tishkov AV, Zhulin IB, Peng J, Nelson SF, Denny JC, Auwerx J, Lu L, Williams RW. Wang X, et al. Among authors: williams rw, williams eg. Nat Commun. 2016 Feb 2;7:10464. doi: 10.1038/ncomms10464. Nat Commun. 2016. PMID: 26833085 Free PMC article.
Bayesian association scan reveals loci associated with human lifespan and linked biomarkers.
McDaid AF, Joshi PK, Porcu E, Komljenovic A, Li H, Sorrentino V, Litovchenko M, Bevers RPJ, Rüeger S, Reymond A, Bochud M, Deplancke B, Williams RW, Robinson-Rechavi M, Paccaud F, Rousson V, Auwerx J, Wilson JF, Kutalik Z. McDaid AF, et al. Among authors: williams rw. Nat Commun. 2017 Jul 27;8:15842. doi: 10.1038/ncomms15842. Nat Commun. 2017. PMID: 28748955 Free PMC article.
An Integrated Systems Genetics and Omics Toolkit to Probe Gene Function.
Li H, Wang X, Rukina D, Huang Q, Lin T, Sorrentino V, Zhang H, Bou Sleiman M, Arends D, McDaid A, Luan P, Ziari N, Velázquez-Villegas LA, Gariani K, Kutalik Z, Schoonjans K, Radcliffe RA, Prins P, Morgenthaler S, Williams RW, Auwerx J. Li H, et al. Among authors: williams rw. Cell Syst. 2018 Jan 24;6(1):90-102.e4. doi: 10.1016/j.cels.2017.10.016. Epub 2017 Nov 30. Cell Syst. 2018. PMID: 29199021 Free article.
Genetic cartography of longevity in humans and mice: Current landscape and horizons.
Hook M, Roy S, Williams EG, Bou Sleiman M, Mozhui K, Nelson JF, Lu L, Auwerx J, Williams RW. Hook M, et al. Among authors: williams rw, williams eg. Biochim Biophys Acta Mol Basis Dis. 2018 Sep;1864(9 Pt A):2718-2732. doi: 10.1016/j.bbadis.2018.01.026. Epub 2018 Feb 2. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 29410319 Free PMC article. Review.
620 results