Wetzel R - Search Results

1

Abeta(1-40) forms five distinct amyloid structures whose beta-sheet contents and fibril stabilities are correlated.

Kodali R, Williams AD, Chemuru S, Wetzel R. Kodali R, et al. Among authors: wetzel r. J Mol Biol. 2010 Aug 20;401(3):503-17. doi: 10.1016/j.jmb.2010.06.023. Epub 2010 Jun 18. J Mol Biol. 2010. PMID: 20600131 Free PMC article.

2

Mapping abeta amyloid fibril secondary structure using scanning proline mutagenesis.

Williams AD, Portelius E, Kheterpal I, Guo JT, Cook KD, Xu Y, Wetzel R. Williams AD, et al. Among authors: wetzel r. J Mol Biol. 2004 Jan 16;335(3):833-42. doi: 10.1016/j.jmb.2003.11.008. J Mol Biol. 2004. PMID: 14687578

3

Alanine scanning mutagenesis of Abeta(1-40) amyloid fibril stability.

Williams AD, Shivaprasad S, Wetzel R. Williams AD, et al. Among authors: wetzel r. J Mol Biol. 2006 Apr 7;357(4):1283-94. doi: 10.1016/j.jmb.2006.01.041. Epub 2006 Jan 30. J Mol Biol. 2006. PMID: 16476445

4

Critical nucleus size for disease-related polyglutamine aggregation is repeat-length dependent.

Kar K, Jayaraman M, Sahoo B, Kodali R, Wetzel R. Kar K, et al. Among authors: wetzel r. Nat Struct Mol Biol. 2011 Mar;18(3):328-36. doi: 10.1038/nsmb.1992. Epub 2011 Feb 13. Nat Struct Mol Biol. 2011. PMID: 21317897 Free PMC article.

5

Slow amyloid nucleation via α-helix-rich oligomeric intermediates in short polyglutamine-containing huntingtin fragments.

Jayaraman M, Kodali R, Sahoo B, Thakur AK, Mayasundari A, Mishra R, Peterson CB, Wetzel R. Jayaraman M, et al. Among authors: wetzel r. J Mol Biol. 2012 Feb 3;415(5):881-99. doi: 10.1016/j.jmb.2011.12.010. Epub 2011 Dec 9. J Mol Biol. 2012. PMID: 22178474 Free PMC article.

6

Inhibiting the nucleation of amyloid structure in a huntingtin fragment by targeting α-helix-rich oligomeric intermediates.

Mishra R, Jayaraman M, Roland BP, Landrum E, Fullam T, Kodali R, Thakur AK, Arduini I, Wetzel R. Mishra R, et al. Among authors: wetzel r. J Mol Biol. 2012 Feb 3;415(5):900-17. doi: 10.1016/j.jmb.2011.12.011. Epub 2011 Dec 9. J Mol Biol. 2012. PMID: 22178478 Free PMC article.

7

Serine phosphorylation suppresses huntingtin amyloid accumulation by altering protein aggregation properties.

Mishra R, Hoop CL, Kodali R, Sahoo B, van der Wel PC, Wetzel R. Mishra R, et al. Among authors: wetzel r. J Mol Biol. 2012 Nov 23;424(1-2):1-14. doi: 10.1016/j.jmb.2012.09.011. Epub 2012 Sep 18. J Mol Biol. 2012. PMID: 22999956 Free PMC article.

8

β-hairpin-mediated nucleation of polyglutamine amyloid formation.

Kar K, Hoop CL, Drombosky KW, Baker MA, Kodali R, Arduini I, van der Wel PC, Horne WS, Wetzel R. Kar K, et al. Among authors: wetzel r. J Mol Biol. 2013 Apr 12;425(7):1183-97. doi: 10.1016/j.jmb.2013.01.016. Epub 2013 Jan 23. J Mol Biol. 2013. PMID: 23353826 Free PMC article.

9

C-Terminal Threonine Reduces Aβ43 Amyloidogenicity Compared with Aβ42.

Chemuru S, Kodali R, Wetzel R. Chemuru S, et al. Among authors: wetzel r. J Mol Biol. 2016 Jan 29;428(2 Pt A):274-291. doi: 10.1016/j.jmb.2015.06.008. Epub 2015 Jun 26. J Mol Biol. 2016. PMID: 26122432 Free PMC article.

10

Rapid α-oligomer formation mediated by the Aβ C terminus initiates an amyloid assembly pathway.

Misra P, Kodali R, Chemuru S, Kar K, Wetzel R. Misra P, et al. Among authors: wetzel r. Nat Commun. 2016 Aug 22;7:12419. doi: 10.1038/ncomms12419. Nat Commun. 2016. PMID: 27546208 Free PMC article.

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