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Central nociceptin/orphanin FQ system elevates food consumption by both increasing energy intake and reducing aversive responsiveness.
Olszewski PK, Grace MK, Fard SS, Le Grevès M, Klockars A, Massi M, Schiöth HB, Levine AS. Olszewski PK, et al. Among authors: klockars a. Am J Physiol Regul Integr Comp Physiol. 2010 Aug;299(2):R655-63. doi: 10.1152/ajpregu.00556.2009. Epub 2010 Apr 28. Am J Physiol Regul Integr Comp Physiol. 2010. PMID: 20427724 Free PMC article.
Fto immunoreactivity is widespread in the rodent brain and abundant in feeding-related sites, but the number of Fto-positive cells is not affected by changes in energy balance.
Olszewski PK, Radomska KJ, Ghimire K, Klockars A, Ingman C, Olszewska AM, Fredriksson R, Levine AS, Schiöth HB. Olszewski PK, et al. Among authors: klockars a. Physiol Behav. 2011 May 3;103(2):248-53. doi: 10.1016/j.physbeh.2011.01.022. Epub 2011 Feb 2. Physiol Behav. 2011. PMID: 21295049
Expression levels of genes encoding melanin concentrating hormone (MCH) and MCH receptor change in taste aversion, but MCH injections do not alleviate aversive responses.
Mitra A, Klockars A, Gosnell BA, Le Grevès M, Olszewski PK, Levine AS, Schiöth HB. Mitra A, et al. Among authors: klockars a. Pharmacol Biochem Behav. 2012 Jan;100(3):581-6. doi: 10.1016/j.pbb.2011.08.009. Epub 2011 Sep 7. Pharmacol Biochem Behav. 2012. PMID: 21925200 Free PMC article.
Neurobeachin, a regulator of synaptic protein targeting, is associated with body fat mass and feeding behavior in mice and body-mass index in humans.
Olszewski PK, Rozman J, Jacobsson JA, Rathkolb B, Strömberg S, Hans W, Klockars A, Alsiö J, Risérus U, Becker L, Hölter SM, Elvert R, Ehrhardt N, Gailus-Durner V, Fuchs H, Fredriksson R, Wolf E, Klopstock T, Wurst W, Levine AS, Marcus C, de Angelis MH, Klingenspor M, Schiöth HB, Kilimann MW. Olszewski PK, et al. Among authors: klockars a. PLoS Genet. 2012;8(3):e1002568. doi: 10.1371/journal.pgen.1002568. Epub 2012 Mar 15. PLoS Genet. 2012. PMID: 22438821 Free PMC article.
Exposure to bisphenol A affects lipid metabolism in Drosophila melanogaster.
Williams MJ, Wang Y, Klockars A, Monica Lind P, Fredriksson R, Schiöth HB. Williams MJ, et al. Among authors: klockars a. Basic Clin Pharmacol Toxicol. 2014 May;114(5):414-20. doi: 10.1111/bcpt.12170. Epub 2013 Dec 11. Basic Clin Pharmacol Toxicol. 2014. PMID: 24215246 Free article.
51 results