Schinkel AH - Search Results

1

Effects of cytochrome P450 3A (CYP3A) and the drug transporters P-glycoprotein (MDR1/ABCB1) and MRP2 (ABCC2) on the pharmacokinetics of lopinavir.

van Waterschoot RA, ter Heine R, Wagenaar E, van der Kruijssen CM, Rooswinkel RW, Huitema AD, Beijnen JH, Schinkel AH. van Waterschoot RA, et al. Among authors: schinkel ah. Br J Pharmacol. 2010 Jul;160(5):1224-33. doi: 10.1111/j.1476-5381.2010.00759.x. Br J Pharmacol. 2010. PMID: 20590614 Free PMC article.

2

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

Schinkel AH, Wagenaar E, van Deemter L, Mol CA, Borst P. Schinkel AH, et al. J Clin Invest. 1995 Oct;96(4):1698-705. doi: 10.1172/JCI118214. J Clin Invest. 1995. PMID: 7560060 Free PMC article.

3

Multidrug resistance and the role of P-glycoprotein knockout mice.

Schinkel AH, Mol CA, Wagenaar E, van Deemter L, Smit JJ, Borst P. Schinkel AH, et al. Eur J Cancer. 1995 Jul-Aug;31A(7-8):1295-8. doi: 10.1016/0959-8049(95)00130-b. Eur J Cancer. 1995. PMID: 7577039 Review.

4

Characterization of the promoter region of the human MDR3 P-glycoprotein gene.

Smit JJ, Mol CA, van Deemter L, Wagenaar E, Schinkel AH, Borst P. Smit JJ, et al. Among authors: schinkel ah. Biochim Biophys Acta. 1995 Mar 14;1261(1):44-56. doi: 10.1016/0167-4781(94)00214-n. Biochim Biophys Acta. 1995. PMID: 7893760

5

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs.

Schinkel AH, Smit JJ, van Tellingen O, Beijnen JH, Wagenaar E, van Deemter L, Mol CA, van der Valk MA, Robanus-Maandag EC, te Riele HP, et al. Schinkel AH, et al. Cell. 1994 May 20;77(4):491-502. doi: 10.1016/0092-8674(94)90212-7. Cell. 1994. PMID: 7910522

6

Classical and novel forms of multidrug resistance and the physiological functions of P-glycoproteins in mammals.

Borst P, Schinkel AH, Smit JJ, Wagenaar E, Van Deemter L, Smith AJ, Eijdems EW, Baas F, Zaman GJ. Borst P, et al. Among authors: schinkel ah. Pharmacol Ther. 1993 Nov;60(2):289-99. doi: 10.1016/0163-7258(93)90011-2. Pharmacol Ther. 1993. PMID: 7912835 Review.

7

N-glycosylation and deletion mutants of the human MDR1 P-glycoprotein.

Schinkel AH, Kemp S, Dollé M, Rudenko G, Wagenaar E. Schinkel AH, et al. J Biol Chem. 1993 Apr 5;268(10):7474-81. J Biol Chem. 1993. PMID: 8096511 Free article.

8

Binding properties of monoclonal antibodies recognizing external epitopes of the human MDR1 P-glycoprotein.

Schinkel AH, Arceci RJ, Smit JJ, Wagenaar E, Baas F, Dollé M, Tsuruo T, Mechetner EB, Roninson IB, Borst P. Schinkel AH, et al. Int J Cancer. 1993 Sep 30;55(3):478-84. doi: 10.1002/ijc.2910550326. Int J Cancer. 1993. PMID: 8104165

9

Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease.

Smit JJ, Schinkel AH, Oude Elferink RP, Groen AK, Wagenaar E, van Deemter L, Mol CA, Ottenhoff R, van der Lugt NM, van Roon MA, et al. Smit JJ, et al. Among authors: schinkel ah. Cell. 1993 Nov 5;75(3):451-62. doi: 10.1016/0092-8674(93)90380-9. Cell. 1993. PMID: 8106172

10

P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs.

Schinkel AH, Wagenaar E, Mol CA, van Deemter L. Schinkel AH, et al. J Clin Invest. 1996 Jun 1;97(11):2517-24. doi: 10.1172/JCI118699. J Clin Invest. 1996. PMID: 8647944 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

302 results

Search Page

Filters