Tanzi RE - Search Results

1

Age-dependent effect of apolipoprotein E4 on functional outcome after controlled cortical impact in mice.

Mannix RC, Zhang J, Park J, Zhang X, Bilal K, Walker K, Tanzi RE, Tesco G, Whalen MJ. Mannix RC, et al. Among authors: tanzi re. J Cereb Blood Flow Metab. 2011 Jan;31(1):351-61. doi: 10.1038/jcbfm.2010.99. Epub 2010 Jun 30. J Cereb Blood Flow Metab. 2011. PMID: 20588316 Free PMC article.

2

Abrogation of the presenilin 1/beta-catenin interaction and preservation of the heterodimeric presenilin 1 complex following caspase activation.

Tesco G, Kim TW, Diehlmann A, Beyreuther K, Tanzi RE. Tesco G, et al. Among authors: tanzi re. J Biol Chem. 1998 Dec 18;273(51):33909-14. doi: 10.1074/jbc.273.51.33909. J Biol Chem. 1998. PMID: 9852041 Free article.

3

Presenilin-mediated modulation of capacitative calcium entry.

Yoo AS, Cheng I, Chung S, Grenfell TZ, Lee H, Pack-Chung E, Handler M, Shen J, Xia W, Tesco G, Saunders AJ, Ding K, Frosch MP, Tanzi RE, Kim TW. Yoo AS, et al. Among authors: tanzi re. Neuron. 2000 Sep;27(3):561-72. doi: 10.1016/s0896-6273(00)00066-0. Neuron. 2000. PMID: 11055438 Free article.

4

GSK3 beta forms a tetrameric complex with endogenous PS1-CTF/NTF and beta-catenin. Effects of the D257/D385A and FAD-linked mutations.

Tesco G, Tanzi RE. Tesco G, et al. Among authors: tanzi re. Ann N Y Acad Sci. 2000;920:227-32. doi: 10.1111/j.1749-6632.2000.tb06927.x. Ann N Y Acad Sci. 2000. PMID: 11193155

5

Caspase activation increases beta-amyloid generation independently of caspase cleavage of the beta-amyloid precursor protein (APP).

Tesco G, Koh YH, Tanzi RE. Tesco G, et al. Among authors: tanzi re. J Biol Chem. 2003 Nov 14;278(46):46074-80. doi: 10.1074/jbc.M307809200. Epub 2003 Sep 5. J Biol Chem. 2003. PMID: 12960154 Free article.

6

Generation of the beta-amyloid peptide and the amyloid precursor protein C-terminal fragment gamma are potentiated by FE65L1.

Chang Y, Tesco G, Jeong WJ, Lindsley L, Eckman EA, Eckman CB, Tanzi RE, Guénette SY. Chang Y, et al. Among authors: tanzi re. J Biol Chem. 2003 Dec 19;278(51):51100-7. doi: 10.1074/jbc.M309561200. Epub 2003 Oct 3. J Biol Chem. 2003. PMID: 14527950 Free article.

7

BACE is degraded via the lysosomal pathway.

Koh YH, von Arnim CA, Hyman BT, Tanzi RE, Tesco G. Koh YH, et al. Among authors: tanzi re. J Biol Chem. 2005 Sep 16;280(37):32499-504. doi: 10.1074/jbc.M506199200. Epub 2005 Jul 20. J Biol Chem. 2005. PMID: 16033761 Free article.

8

APP substitutions V715F and L720P alter PS1 conformation and differentially affect Abeta and AICD generation.

Tesco G, Ginestroni A, Hiltunen M, Kim M, Dolios G, Hyman BT, Wang R, Berezovska O, Tanzi RE. Tesco G, et al. Among authors: tanzi re. J Neurochem. 2005 Oct;95(2):446-56. doi: 10.1111/j.1471-4159.2005.03381.x. Epub 2005 Aug 8. J Neurochem. 2005. PMID: 16086682 Free article.

9

Hypocapnia induces caspase-3 activation and increases Abeta production.

Xie Z, Moir RD, Romano DM, Tesco G, Kovacs DM, Tanzi RE. Xie Z, et al. Among authors: tanzi re. Neurodegener Dis. 2004;1(1):29-37. doi: 10.1159/000076667. Neurodegener Dis. 2004. PMID: 16908971

10

Ubiquilin 1 modulates amyloid precursor protein trafficking and Abeta secretion.

Hiltunen M, Lu A, Thomas AV, Romano DM, Kim M, Jones PB, Xie Z, Kounnas MZ, Wagner SL, Berezovska O, Hyman BT, Tesco G, Bertram L, Tanzi RE. Hiltunen M, et al. Among authors: tanzi re. J Biol Chem. 2006 Oct 27;281(43):32240-53. doi: 10.1074/jbc.M603106200. Epub 2006 Aug 31. J Biol Chem. 2006. PMID: 16945923 Free article.

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