Kaiser P - Search Results

1

Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase.

Aghajan M, Jonai N, Flick K, Fu F, Luo M, Cai X, Ouni I, Pierce N, Tang X, Lomenick B, Damoiseaux R, Hao R, Del Moral PM, Verma R, Li Y, Li C, Houk KN, Jung ME, Zheng N, Huang L, Deshaies RJ, Kaiser P, Huang J. Aghajan M, et al. Among authors: kaiser p. Nat Biotechnol. 2010 Jul;28(7):738-42. doi: 10.1038/nbt.1645. Epub 2010 Jun 27. Nat Biotechnol. 2010. PMID: 20581845 Free PMC article.

2

Regulation of transcription by ubiquitination without proteolysis: Cdc34/SCF(Met30)-mediated inactivation of the transcription factor Met4.

Kaiser P, Flick K, Wittenberg C, Reed SI. Kaiser P, et al. Cell. 2000 Aug 4;102(3):303-14. doi: 10.1016/s0092-8674(00)00036-2. Cell. 2000. PMID: 10975521 Free article.

3

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line.

Strohmaier H, Spruck CH, Kaiser P, Won KA, Sangfelt O, Reed SI. Strohmaier H, et al. Among authors: kaiser p. Nature. 2001 Sep 20;413(6853):316-22. doi: 10.1038/35095076. Nature. 2001. PMID: 11565034

4

Proteolysis-independent regulation of the transcription factor Met4 by a single Lys 48-linked ubiquitin chain.

Flick K, Ouni I, Wohlschlegel JA, Capati C, McDonald WH, Yates JR, Kaiser P. Flick K, et al. Among authors: kaiser p. Nat Cell Biol. 2004 Jul;6(7):634-41. doi: 10.1038/ncb1143. Epub 2004 Jun 20. Nat Cell Biol. 2004. PMID: 15208638

5

The yeast ubiquitin ligase SCFMet30 regulates heavy metal response.

Yen JL, Su NY, Kaiser P. Yen JL, et al. Among authors: kaiser p. Mol Biol Cell. 2005 Apr;16(4):1872-82. doi: 10.1091/mbc.e04-12-1130. Epub 2005 Feb 2. Mol Biol Cell. 2005. PMID: 15689486 Free PMC article.

6

The F-box protein Met30 is required for multiple steps in the budding yeast cell cycle.

Su NY, Flick K, Kaiser P. Su NY, et al. Among authors: kaiser p. Mol Cell Biol. 2005 May;25(10):3875-85. doi: 10.1128/MCB.25.10.3875-3885.2005. Mol Cell Biol. 2005. PMID: 15870262 Free PMC article.

7

Global approaches to understanding ubiquitination.

Kaiser P, Huang L. Kaiser P, et al. Genome Biol. 2005;6(10):233. doi: 10.1186/gb-2005-6-10-233. Epub 2005 Sep 29. Genome Biol. 2005. PMID: 16207362 Free PMC article. Review.

8

An integrated mass spectrometry-based proteomic approach: quantitative analysis of tandem affinity-purified in vivo cross-linked protein complexes (QTAX) to decipher the 26 S proteasome-interacting network.

Guerrero C, Tagwerker C, Kaiser P, Huang L. Guerrero C, et al. Among authors: kaiser p. Mol Cell Proteomics. 2006 Feb;5(2):366-78. doi: 10.1074/mcp.M500303-MCP200. Epub 2005 Nov 10. Mol Cell Proteomics. 2006. PMID: 16284124 Free article.

9

A tandem affinity tag for two-step purification under fully denaturing conditions: application in ubiquitin profiling and protein complex identification combined with in vivocross-linking.

Tagwerker C, Flick K, Cui M, Guerrero C, Dou Y, Auer B, Baldi P, Huang L, Kaiser P. Tagwerker C, et al. Among authors: kaiser p. Mol Cell Proteomics. 2006 Apr;5(4):737-48. doi: 10.1074/mcp.M500368-MCP200. Epub 2006 Jan 23. Mol Cell Proteomics. 2006. PMID: 16432255 Free article.

10

A ubiquitin-interacting motif protects polyubiquitinated Met4 from degradation by the 26S proteasome.

Flick K, Raasi S, Zhang H, Yen JL, Kaiser P. Flick K, et al. Among authors: kaiser p. Nat Cell Biol. 2006 May;8(5):509-15. doi: 10.1038/ncb1402. Epub 2006 Apr 9. Nat Cell Biol. 2006. PMID: 16604062

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