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The angiotensin-converting enzyme 2/angiogenesis-(1-7)/Mas axis confers cardiopulmonary protection against lung fibrosis and pulmonary hypertension.
Shenoy V, Ferreira AJ, Qi Y, Fraga-Silva RA, Díez-Freire C, Dooies A, Jun JY, Sriramula S, Mariappan N, Pourang D, Venugopal CS, Francis J, Reudelhuber T, Santos RA, Patel JM, Raizada MK, Katovich MJ. Shenoy V, et al. Among authors: jun jy. Am J Respir Crit Care Med. 2010 Oct 15;182(8):1065-72. doi: 10.1164/rccm.200912-1840OC. Epub 2010 Jun 25. Am J Respir Crit Care Med. 2010. PMID: 20581171 Free PMC article.
ACE2 activation promotes antithrombotic activity.
Fraga-Silva RA, Sorg BS, Wankhede M, Dedeugd C, Jun JY, Baker MB, Li Y, Castellano RK, Katovich MJ, Raizada MK, Ferreira AJ. Fraga-Silva RA, et al. Among authors: jun jy. Mol Med. 2010 May-Jun;16(5-6):210-5. doi: 10.2119/molmed.2009.00160. Epub 2010 Jan 22. Mol Med. 2010. PMID: 20111697 Free PMC article.
Diminazene attenuates pulmonary hypertension and improves angiogenic progenitor cell functions in experimental models.
Shenoy V, Gjymishka A, Jarajapu YP, Qi Y, Afzal A, Rigatto K, Ferreira AJ, Fraga-Silva RA, Kearns P, Douglas JY, Agarwal D, Mubarak KK, Bradford C, Kennedy WR, Jun JY, Rathinasabapathy A, Bruce E, Gupta D, Cardounel AJ, Mocco J, Patel JM, Francis J, Grant MB, Katovich MJ, Raizada MK. Shenoy V, et al. Among authors: jun jy. Am J Respir Crit Care Med. 2013 Mar 15;187(6):648-57. doi: 10.1164/rccm.201205-0880OC. Epub 2013 Jan 31. Am J Respir Crit Care Med. 2013. PMID: 23370913 Free PMC article.
Brain microglial cytokines in neurogenic hypertension.
Shi P, Diez-Freire C, Jun JY, Qi Y, Katovich MJ, Li Q, Sriramula S, Francis J, Sumners C, Raizada MK. Shi P, et al. Among authors: jun jy. Hypertension. 2010 Aug;56(2):297-303. doi: 10.1161/HYPERTENSIONAHA.110.150409. Epub 2010 Jun 14. Hypertension. 2010. PMID: 20547972 Free PMC article.
Chronic knockdown of the nucleus of the solitary tract AT1 receptors increases blood inflammatory-endothelial progenitor cell ratio and exacerbates hypertension in the spontaneously hypertensive rat.
Shan Z, Zubcevic J, Shi P, Jun JY, Dong Y, Murça TM, Lamont GJ, Cuadra A, Yuan W, Qi Y, Li Q, Paton JF, Katovich MJ, Sumners C, Raizada MK. Shan Z, et al. Among authors: jun jy. Hypertension. 2013 Jun;61(6):1328-33. doi: 10.1161/HYPERTENSIONAHA.111.00156. Epub 2013 Apr 1. Hypertension. 2013. PMID: 23547238 Free PMC article.
Altered inflammatory response is associated with an impaired autonomic input to the bone marrow in the spontaneously hypertensive rat.
Zubcevic J, Jun JY, Kim S, Perez PD, Afzal A, Shan Z, Li W, Santisteban MM, Yuan W, Febo M, Mocco J, Feng Y, Scott E, Baekey DM, Raizada MK. Zubcevic J, et al. Among authors: jun jy. Hypertension. 2014 Mar;63(3):542-50. doi: 10.1161/HYPERTENSIONAHA.113.02722. Epub 2013 Dec 23. Hypertension. 2014. PMID: 24366083 Free PMC article.
186 results