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Lineage-specific pathogenicity, immune evasion, and virological features of SARS-CoV-2 BA.2.86/JN.1 and EG.5.1/HK.3.
Liu Y, Zhao X, Shi J, Wang Y, Liu H, Hu YF, Hu B, Shuai H, Yuen TT, Chai Y, Liu F, Gong HR, Li J, Wang X, Jiang S, Zhang X, Zhang Y, Li X, Wang L, Hartnoll M, Zhu T, Hou Y, Huang X, Yoon C, Wang Y, He Y, Zhou M, Du L, Zhang X, Chan WM, Chen LL, Cai JP, Yuan S, Zhou J, Huang JD, Yuen KY, To KK, Chan JF, Zhang BZ, Sun L, Wang P, Chu H. Liu Y, et al. Among authors: chan wm. Nat Commun. 2024 Oct 9;15(1):8728. doi: 10.1038/s41467-024-53033-7. Nat Commun. 2024. PMID: 39379369 Free PMC article.
A cell type-aware framework for nominating non-coding variants in Mendelian regulatory disorders.
Lee AS, Ayers LJ, Kosicki M, Chan WM, Fozo LN, Pratt BM, Collins TE, Zhao B, Rose MF, Sanchis-Juan A, Fu JM, Wong I, Zhao X, Tenney AP, Lee C, Laricchia KM, Barry BJ, Bradford VR, Jurgens JA, England EM, Lek M, MacArthur DG, Lee EA, Talkowski ME, Brand H, Pennacchio LA, Engle EC. Lee AS, et al. Among authors: chan wm. Nat Commun. 2024 Sep 27;15(1):8268. doi: 10.1038/s41467-024-52463-7. Nat Commun. 2024. PMID: 39333082 Free PMC article.
Corrigendum to "The significance of recurrent de novo amino acid substitutions that emerged during chronic SARS-CoV-2 infection: an observational study" [eBioMedicine, 2024;107:105273].
Ip JD, Chu WM, Chan WM, Chu AW, Leung RC, Peng Q, Tam AR, Chan BP, Cai JP, Yuen KY, Kok KH, Shi Y, Hung IF, To KK. Ip JD, et al. Among authors: chan wm. EBioMedicine. 2024 Oct;108:105371. doi: 10.1016/j.ebiom.2024.105371. Epub 2024 Sep 24. EBioMedicine. 2024. PMID: 39321502 Free PMC article. No abstract available.
Gene identification for ocular congenital cranial motor neuron disorders using human sequencing, zebrafish screening, and protein binding microarrays.
Jurgens JA, Matos Ruiz PM, King J, Foster EE, Berube L, Chan WM, Barry BJ, Jeong R, Rothman E, Whitman MC, MacKinnon S, Rivera-Quiles C, Pratt BM, Easterbrooks T, Mensching FM, Di Gioia SA, Pais L, England EM, de Berardinis T, Magli A, Koc F, Asakawa K, Kawakami K, O'Donnell-Luria A, Hunter DG, Robson CD, Bulyk ML, Engle EC. Jurgens JA, et al. Among authors: chan wm. bioRxiv [Preprint]. 2024 Sep 15:2024.09.12.612713. doi: 10.1101/2024.09.12.612713. bioRxiv. 2024. PMID: 39314366 Free PMC article. Preprint.
Identification of novel small-molecule inhibitors of SARS-CoV-2 by chemical genetics.
Chan CC, Guo Q, Chan JF, Tang K, Cai JP, Chik KK, Huang Y, Dai M, Qin B, Ong CP, Chu AW, Chan WM, Ip JD, Wen L, Tsang JO, Wang TY, Xie Y, Qin Z, Cao J, Ye ZW, Chu H, To KK, Ge XY, Ni T, Jin DY, Cui S, Yuen KY, Yuan S. Chan CC, et al. Among authors: chan wm. Acta Pharm Sin B. 2024 Sep;14(9):4028-4044. doi: 10.1016/j.apsb.2024.05.026. Epub 2024 May 31. Acta Pharm Sin B. 2024. PMID: 39309487 Free PMC article.
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