Naismith JH - Search Results

1

The serine palmitoyltransferase from Sphingomonas wittichii RW1: An interesting link to an unusual acyl carrier protein.

Raman MC, Johnson KA, Clarke DJ, Naismith JH, Campopiano DJ. Raman MC, et al. Among authors: naismith jh. Biopolymers. 2010 Sep;93(9):811-22. doi: 10.1002/bip.21482. Biopolymers. 2010. PMID: 20578000 Free article.

2

The structure of serine palmitoyltransferase; gateway to sphingolipid biosynthesis.

Yard BA, Carter LG, Johnson KA, Overton IM, Dorward M, Liu H, McMahon SA, Oke M, Puech D, Barton GJ, Naismith JH, Campopiano DJ. Yard BA, et al. Among authors: naismith jh. J Mol Biol. 2007 Jul 27;370(5):870-86. doi: 10.1016/j.jmb.2007.04.086. Epub 2007 May 10. J Mol Biol. 2007. PMID: 17559874

3

The external aldimine form of serine palmitoyltransferase: structural, kinetic, and spectroscopic analysis of the wild-type enzyme and HSAN1 mutant mimics.

Raman MCC, Johnson KA, Yard BA, Lowther J, Carter LG, Naismith JH, Campopiano DJ. Raman MCC, et al. Among authors: naismith jh. J Biol Chem. 2009 Jun 19;284(25):17328-17339. doi: 10.1074/jbc.M109.008680. Epub 2009 Apr 17. J Biol Chem. 2009. PMID: 19376777 Free PMC article.

4

Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation.

Lowther J, Yard BA, Johnson KA, Carter LG, Bhat VT, Raman MC, Clarke DJ, Ramakers B, McMahon SA, Naismith JH, Campopiano DJ. Lowther J, et al. Among authors: naismith jh. Mol Biosyst. 2010 Sep;6(9):1682-93. doi: 10.1039/c003743e. Epub 2010 May 5. Mol Biosyst. 2010. PMID: 20445930 Free PMC article.

5

Structural, mechanistic and regulatory studies of serine palmitoyltransferase.

Lowther J, Naismith JH, Dunn TM, Campopiano DJ. Lowther J, et al. Among authors: naismith jh. Biochem Soc Trans. 2012 Jun 1;40(3):547-54. doi: 10.1042/BST20110769. Biochem Soc Trans. 2012. PMID: 22616865 Free article. Review.

6

The chemical basis of serine palmitoyltransferase inhibition by myriocin.

Wadsworth JM, Clarke DJ, McMahon SA, Lowther JP, Beattie AE, Langridge-Smith PR, Broughton HB, Dunn TM, Naismith JH, Campopiano DJ. Wadsworth JM, et al. Among authors: naismith jh. J Am Chem Soc. 2013 Sep 25;135(38):14276-85. doi: 10.1021/ja4059876. Epub 2013 Sep 11. J Am Chem Soc. 2013. PMID: 23957439 Free article.

7

Use of isotopically labeled substrates reveals kinetic differences between human and bacterial serine palmitoyltransferase.

Harrison PJ, Gable K, Somashekarappa N, Kelly V, Clarke DJ, Naismith JH, Dunn TM, Campopiano DJ. Harrison PJ, et al. Among authors: naismith jh. J Lipid Res. 2019 May;60(5):953-962. doi: 10.1194/jlr.M089367. Epub 2019 Feb 21. J Lipid Res. 2019. PMID: 30792183 Free PMC article.

8

Using the pimeloyl-CoA synthetase adenylation fold to synthesize fatty acid thioesters.

Wang M, Moynié L, Harrison PJ, Kelly V, Piper A, Naismith JH, Campopiano DJ. Wang M, et al. Among authors: naismith jh. Nat Chem Biol. 2017 Jun;13(6):660-667. doi: 10.1038/nchembio.2361. Epub 2017 Apr 17. Nat Chem Biol. 2017. PMID: 28414710 Free article.

9

[No title available]

[No authors listed] [No authors listed] PMID: 33487381

10

The second enzyme in pyrrolnitrin biosynthetic pathway is related to the heme-dependent dioxygenase superfamily.

De Laurentis W, Khim L, Anderson JL, Adam A, Johnson KA, Phillips RS, Chapman SK, van Pee KH, Naismith JH. De Laurentis W, et al. Among authors: naismith jh. Biochemistry. 2007 Oct 30;46(43):12393-404. doi: 10.1021/bi7012189. Epub 2007 Oct 9. Biochemistry. 2007. PMID: 17924666 Free PMC article.

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