Junttila I - Search Results

1

Sustained IL-4 exposure leads to a novel pathway for hemophagocytosis, inflammation, and tissue macrophage accumulation.

Milner JD, Orekov T, Ward JM, Cheng L, Torres-Velez F, Junttila I, Sun G, Buller M, Morris SC, Finkelman FD, Paul WE. Milner JD, et al. Among authors: junttila i. Blood. 2010 Oct 7;116(14):2476-83. doi: 10.1182/blood-2009-11-255174. Epub 2010 Jun 22. Blood. 2010. PMID: 20570861 Free PMC article.

2

Regulation of Jak2 tyrosine kinase by protein kinase C during macrophage differentiation of IL-3-dependent myeloid progenitor cells.

Kovanen PE, Junttila I, Takaluoma K, Saharinen P, Valmu L, Li W, Silvennoinen O. Kovanen PE, et al. Among authors: junttila i. Blood. 2000 Mar 1;95(5):1626-32. Blood. 2000. PMID: 10688817 Free article.

3

Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity.

Junttila IS, Mizukami K, Dickensheets H, Meier-Schellersheim M, Yamane H, Donnelly RP, Paul WE. Junttila IS, et al. J Exp Med. 2008 Oct 27;205(11):2595-608. doi: 10.1084/jem.20080452. Epub 2008 Oct 13. J Exp Med. 2008. PMID: 18852293 Free PMC article.

4

Type I IL-4Rs selectively activate IRS-2 to induce target gene expression in macrophages.

Heller NM, Qi X, Junttila IS, Shirey KA, Vogel SN, Paul WE, Keegan AD. Heller NM, et al. Sci Signal. 2008 Dec 23;1(51):ra17. doi: 10.1126/scisignal.1164795. Sci Signal. 2008. PMID: 19109239 Free PMC article.

5

The transcription factor GATA3 actively represses RUNX3 protein-regulated production of interferon-gamma.

Yagi R, Junttila IS, Wei G, Urban JF Jr, Zhao K, Paul WE, Zhu J. Yagi R, et al. Immunity. 2010 Apr 23;32(4):507-17. doi: 10.1016/j.immuni.2010.04.004. Epub 2010 Apr 15. Immunity. 2010. PMID: 20399120 Free PMC article.

6

Cytokine-induced cytokine production by conventional and innate lymphoid cells.

Guo L, Junttila IS, Paul WE. Guo L, et al. Trends Immunol. 2012 Dec;33(12):598-606. doi: 10.1016/j.it.2012.07.006. Epub 2012 Sep 5. Trends Immunol. 2012. PMID: 22959641 Free PMC article. Review.

7

Redirecting cell-type specific cytokine responses with engineered interleukin-4 superkines.

Junttila IS, Creusot RJ, Moraga I, Bates DL, Wong MT, Alonso MN, Suhoski MM, Lupardus P, Meier-Schellersheim M, Engleman EG, Utz PJ, Fathman CG, Paul WE, Garcia KC. Junttila IS, et al. Nat Chem Biol. 2012 Dec;8(12):990-8. doi: 10.1038/nchembio.1096. Epub 2012 Oct 28. Nat Chem Biol. 2012. PMID: 23103943 Free PMC article.

8

Efficient cytokine-induced IL-13 production by mast cells requires both IL-33 and IL-3.

Junttila IS, Watson C, Kummola L, Chen X, Hu-Li J, Guo L, Yagi R, Paul WE. Junttila IS, et al. J Allergy Clin Immunol. 2013 Sep;132(3):704-712.e10. doi: 10.1016/j.jaci.2013.03.033. Epub 2013 May 14. J Allergy Clin Immunol. 2013. PMID: 23683462 Free PMC article.

9

TSLP expression: analysis with a ZsGreen TSLP reporter mouse.

Dewas C, Chen X, Honda T, Junttila I, Linton J, Udey MC, Porcella SF, Sturdevant DE, Feigenbaum L, Koo L, Williams J, Paul WE. Dewas C, et al. Among authors: junttila i. J Immunol. 2015 Feb 1;194(3):1372-80. doi: 10.4049/jimmunol.1400519. Epub 2014 Dec 24. J Immunol. 2015. PMID: 25539812 Free PMC article.

10

IL-7Rα Expression Regulates Murine Dendritic Cell Sensitivity to Thymic Stromal Lymphopoietin.

Kummola L, Ortutay Z, Chen X, Caucheteux S, Hämäläinen S, Aittomäki S, Yagi R, Zhu J, Pesu M, Paul WE, Junttila IS. Kummola L, et al. J Immunol. 2017 May 15;198(10):3909-3918. doi: 10.4049/jimmunol.1600753. Epub 2017 Apr 12. J Immunol. 2017. PMID: 28404633 Free PMC article.

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