Stewart PW - Search Results

1

Effects of uridine diphosphate glucuronosyltransferase 2B7 and 1A7 pharmacogenomics and patient clinical parameters on steady-state mycophenolic acid pharmacokinetics in glomerulonephritis.

Joy MS, Boyette T, Hu Y, Wang J, La M, Hogan SL, Stewart PW, Falk RJ, Dooley MA, Smith PC. Joy MS, et al. Among authors: stewart pw. Eur J Clin Pharmacol. 2010 Nov;66(11):1119-30. doi: 10.1007/s00228-010-0846-x. Epub 2010 Jun 22. Eur J Clin Pharmacol. 2010. PMID: 20567810 Free PMC article.

2

Variation in oral clearance of saquinavir is predicted by CYP3A5*1 genotype but not by enterocyte content of cytochrome P450 3A5.

Mouly SJ, Matheny C, Paine MF, Smith G, Lamba J, Lamba V, Pusek SN, Schuetz EG, Stewart PW, Watkins PB. Mouly SJ, et al. Among authors: stewart pw. Clin Pharmacol Ther. 2005 Dec;78(6):605-18. doi: 10.1016/j.clpt.2005.08.014. Clin Pharmacol Ther. 2005. PMID: 16338276 Clinical Trial.

3

Altered bile acid and coproporphyrin-I disposition in patients with autosomal dominant polycystic kidney disease.

Tiley JB, Beaudoin JJ, Derebail VK, Murphy WA, Park CC, Veeder JA, Tran L, Beers JL, Jia W, Stewart PW, Brouwer KLR. Tiley JB, et al. Among authors: stewart pw. Br J Clin Pharmacol. 2024 Sep 24. doi: 10.1111/bcp.16221. Online ahead of print. Br J Clin Pharmacol. 2024. PMID: 39317666

4

Do men and women differ in proximal small intestinal CYP3A or P-glycoprotein expression?

Paine MF, Ludington SS, Chen ML, Stewart PW, Huang SM, Watkins PB. Paine MF, et al. Among authors: stewart pw. Drug Metab Dispos. 2005 Mar;33(3):426-33. doi: 10.1124/dmd.104.002469. Epub 2004 Dec 17. Drug Metab Dispos. 2005. PMID: 15608139

5

Risk factors for development of cholestatic drug-induced liver injury: inhibition of hepatic basolateral bile acid transporters multidrug resistance-associated proteins 3 and 4.

Köck K, Ferslew BC, Netterberg I, Yang K, Urban TJ, Swaan PW, Stewart PW, Brouwer KL. Köck K, et al. Among authors: stewart pw. Drug Metab Dispos. 2014 Apr;42(4):665-74. doi: 10.1124/dmd.113.054304. Epub 2013 Oct 23. Drug Metab Dispos. 2014. PMID: 24154606 Free PMC article.

6

An experimental approach to evaluate the impact of impaired transport function on hepatobiliary drug disposition using Mrp2-deficient TR- rat sandwich-cultured hepatocytes in combination with Bcrp knockdown.

Yang K, Pfeifer ND, Hardwick RN, Yue W, Stewart PW, Brouwer KL. Yang K, et al. Among authors: stewart pw. Mol Pharm. 2014 Mar 3;11(3):766-75. doi: 10.1021/mp400471e. Epub 2014 Jan 30. Mol Pharm. 2014. PMID: 24410402 Free PMC article.

7

Altered morphine glucuronide and bile acid disposition in patients with nonalcoholic steatohepatitis.

Ferslew BC, Johnston CK, Tsakalozou E, Bridges AS, Paine MF, Jia W, Stewart PW, Barritt AS 4th, Brouwer KL. Ferslew BC, et al. Among authors: stewart pw. Clin Pharmacol Ther. 2015 Apr;97(4):419-27. doi: 10.1002/cpt.66. Epub 2015 Mar 15. Clin Pharmacol Ther. 2015. PMID: 25669174 Free PMC article.

8

Transporter-Mediated Alterations in Patients With NASH Increase Systemic and Hepatic Exposure to an OATP and MRP2 Substrate.

Ali I, Slizgi JR, Kaullen JD, Ivanovic M, Niemi M, Stewart PW, Barritt AS 4th, Brouwer KLR. Ali I, et al. Among authors: stewart pw. Clin Pharmacol Ther. 2017 Dec 22:10.1002/cpt.997. doi: 10.1002/cpt.997. Online ahead of print. Clin Pharmacol Ther. 2017. PMID: 29271075 Free PMC article.

9

HIV-1 viral load and phenotypic antiretroviral drug resistance assays based on reverse transcriptase activity in comparison to amplification based HIV-1 RNA and genotypic assays.

Napravnik S, Cachafeiro A, Stewart P, Eron JJ Jr, Fiscus SA. Napravnik S, et al. J Clin Virol. 2010 Jan;47(1):18-22. doi: 10.1016/j.jcv.2009.10.001. Epub 2009 Nov 5. J Clin Virol. 2010. PMID: 19896416 Free PMC article.

10

Sex and menopausal status influence human dietary requirements for the nutrient choline.

Fischer LM, daCosta KA, Kwock L, Stewart PW, Lu TS, Stabler SP, Allen RH, Zeisel SH. Fischer LM, et al. Among authors: stewart pw. Am J Clin Nutr. 2007 May;85(5):1275-85. doi: 10.1093/ajcn/85.5.1275. Am J Clin Nutr. 2007. PMID: 17490963 Free PMC article. Clinical Trial.

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