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Page 1
Phase 1b study of pegylated interferon lambda 1 with or without ribavirin in patients with chronic genotype 1 hepatitis C virus infection.
Muir AJ, Shiffman ML, Zaman A, Yoffe B, de la Torre A, Flamm S, Gordon SC, Marotta P, Vierling JM, Lopez-Talavera JC, Byrnes-Blake K, Fontana D, Freeman J, Gray T, Hausman D, Hunder NN, Lawitz E. Muir AJ, et al. Hepatology. 2010 Sep;52(3):822-32. doi: 10.1002/hep.23743. Hepatology. 2010. PMID: 20564352 Clinical Trial.
Recombinant interleukin-21 plus sorafenib for metastatic renal cell carcinoma: a phase 1/2 study.
Bhatia S, Curti B, Ernstoff MS, Gordon M, Heath EI, Miller WH Jr, Puzanov I, Quinn DI, Flaig TW, VanVeldhuizen P, Byrnes-Blake K, Freeman JA, Bittner R, Hunder N, Souza S, Thompson JA. Bhatia S, et al. Among authors: byrnes blake k. J Immunother Cancer. 2014 Jan 27;2:2. doi: 10.1186/2051-1426-2-2. eCollection 2014. J Immunother Cancer. 2014. PMID: 24829759 Free PMC article.
Nonclinical Profile of BLZ-100, a Tumor-Targeting Fluorescent Imaging Agent.
Parrish-Novak J, Byrnes-Blake K, Lalayeva N, Burleson S, Fidel J, Gilmore R, Gayheart-Walsten P, Bricker GA, Crumb WJ Jr, Tarlo KS, Hansen S, Wiss V, Malta E, Dernell WS, Olson JM, Miller DM. Parrish-Novak J, et al. Among authors: byrnes blake k. Int J Toxicol. 2017 Mar/Apr;36(2):104-112. doi: 10.1177/1091581817697685. Epub 2017 Mar 17. Int J Toxicol. 2017. PMID: 28403743 Free PMC article.
A first-in-human study of BLZ-100 (tozuleristide) demonstrates tolerability and safety in skin cancer patients.
Yamada M, Miller DM, Lowe M, Rowe C, Wood D, Soyer HP, Byrnes-Blake K, Parrish-Novak J, Ishak L, Olson JM, Brandt G, Griffin P, Spelman L, Prow TW. Yamada M, et al. Among authors: byrnes blake k. Contemp Clin Trials Commun. 2021 Aug 4;23:100830. doi: 10.1016/j.conctc.2021.100830. eCollection 2021 Sep. Contemp Clin Trials Commun. 2021. PMID: 34401600 Free PMC article.
Phase 1 Safety, Pharmacokinetics, and Fluorescence Imaging Study of Tozuleristide (BLZ-100) in Adults With Newly Diagnosed or Recurrent Gliomas.
Patil CG, Walker DG, Miller DM, Butte P, Morrison B, Kittle DS, Hansen SJ, Nufer KL, Byrnes-Blake KA, Yamada M, Lin LL, Pham K, Perry J, Parrish-Novak J, Ishak L, Prow T, Black K, Mamelak AN. Patil CG, et al. Among authors: byrnes blake ka. Neurosurgery. 2019 Oct 1;85(4):E641-E649. doi: 10.1093/neuros/nyz125. Neurosurgery. 2019. PMID: 31069381 Clinical Trial.
Interleukin (IL) 31 induces in cynomolgus monkeys a rapid and intense itch response that can be inhibited by an IL-31 neutralizing antibody.
Lewis KE, Holdren MS, Maurer MF, Underwood S, Meengs B, Julien SH, Byrnes-Blake KA, Freeman JA, Bukowski TR, Wolf AC, Hamacher NB, Rixon MW, Dillon SR. Lewis KE, et al. Among authors: byrnes blake ka. J Eur Acad Dermatol Venereol. 2017 Jan;31(1):142-150. doi: 10.1111/jdv.13794. Epub 2016 Aug 8. J Eur Acad Dermatol Venereol. 2017. PMID: 27501029
A potent peptide-steroid conjugate accumulates in cartilage and reverses arthritis without evidence of systemic corticosteroid exposure.
Cook Sangar ML, Girard EJ, Hopping G, Yin C, Pakiam F, Brusniak MY, Nguyen E, Ruff R, Gewe MM, Byrnes-Blake K, Nairn NW, Miller DM, Mehlin C, Strand AD, Mhyre AJ, Correnti CE, Strong RK, Simon JA, Olson JM. Cook Sangar ML, et al. Among authors: byrnes blake k. Sci Transl Med. 2020 Mar 4;12(533):eaay1041. doi: 10.1126/scitranslmed.aay1041. Sci Transl Med. 2020. PMID: 32132215
20 results