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A novel biased allosteric compound inhibitor of parturition selectively impedes the prostaglandin F2alpha-mediated Rho/ROCK signaling pathway.
Goupil E, Tassy D, Bourguet C, Quiniou C, Wisehart V, Pétrin D, Le Gouill C, Devost D, Zingg HH, Bouvier M, Saragovi HU, Chemtob S, Lubell WD, Claing A, Hébert TE, Laporte SA. Goupil E, et al. Among authors: quiniou c. J Biol Chem. 2010 Aug 13;285(33):25624-36. doi: 10.1074/jbc.M110.115196. Epub 2010 Jun 15. J Biol Chem. 2010. PMID: 20551320 Free PMC article.
Modulation of pro-inflammatory gene expression by nuclear lysophosphatidic acid receptor type-1.
Gobeil F Jr, Bernier SG, Vazquez-Tello A, Brault S, Beauchamp MH, Quiniou C, Marrache AM, Checchin D, Sennlaub F, Hou X, Nader M, Bkaily G, Ribeiro-da-Silva A, Goetzl EJ, Chemtob S. Gobeil F Jr, et al. Among authors: quiniou c. J Biol Chem. 2003 Oct 3;278(40):38875-83. doi: 10.1074/jbc.M212481200. Epub 2003 Jul 7. J Biol Chem. 2003. PMID: 12847111 Free article.
Development of a novel noncompetitive antagonist of IL-1 receptor.
Quiniou C, Sapieha P, Lahaie I, Hou X, Brault S, Beauchamp M, Leduc M, Rihakova L, Joyal JS, Nadeau S, Heveker N, Lubell W, Sennlaub F, Gobeil F Jr, Miller G, Pshezhetsky AV, Chemtob S. Quiniou C, et al. J Immunol. 2008 May 15;180(10):6977-87. doi: 10.4049/jimmunol.180.10.6977. J Immunol. 2008. PMID: 18453620
43 results