Donehower LA - Search Results

1

Disrupting circadian homeostasis of sympathetic signaling promotes tumor development in mice.

Lee S, Donehower LA, Herron AJ, Moore DD, Fu L. Lee S, et al. Among authors: donehower la. PLoS One. 2010 Jun 7;5(6):e10995. doi: 10.1371/journal.pone.0010995. PLoS One. 2010. PMID: 20539819 Free PMC article.

2

Mouse tissues that undergo neoplastic progression after K-Ras activation are distinguished by nuclear translocation of phospho-Erk1/2 and robust tumor suppressor responses.

Parikh N, Shuck RL, Nguyen TA, Herron A, Donehower LA. Parikh N, et al. Among authors: donehower la. Mol Cancer Res. 2012 Jun;10(6):845-55. doi: 10.1158/1541-7786.MCR-12-0089. Epub 2012 Apr 24. Mol Cancer Res. 2012. PMID: 22532587 Free PMC article.

3

MMP13, Birc2 (cIAP1), and Birc3 (cIAP2), amplified on chromosome 9, collaborate with p53 deficiency in mouse osteosarcoma progression.

Ma O, Cai WW, Zender L, Dayaram T, Shen J, Herron AJ, Lowe SW, Man TK, Lau CC, Donehower LA. Ma O, et al. Among authors: donehower la. Cancer Res. 2009 Mar 15;69(6):2559-67. doi: 10.1158/0008-5472.CAN-08-2929. Epub 2009 Mar 10. Cancer Res. 2009. PMID: 19276372 Free PMC article.

4

Absence of Wip1 partially rescues Atm deficiency phenotypes in mice.

Darlington Y, Nguyen TA, Moon SH, Herron A, Rao P, Zhu C, Lu X, Donehower LA. Darlington Y, et al. Among authors: donehower la. Oncogene. 2012 Mar 1;31(9):1155-65. doi: 10.1038/onc.2011.303. Epub 2011 Jul 18. Oncogene. 2012. PMID: 21765465 Free PMC article.

5

Timed somatic deletion of p53 in mice reveals age-associated differences in tumor progression.

Hinkal G, Parikh N, Donehower LA. Hinkal G, et al. Among authors: donehower la. PLoS One. 2009 Aug 14;4(8):e6654. doi: 10.1371/journal.pone.0006654. PLoS One. 2009. PMID: 19680549 Free PMC article.

6

Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma.

Cancer Genome Atlas Research Network. Electronic address: wheeler@bcm.edu; Cancer Genome Atlas Research Network. Cancer Genome Atlas Research Network. Electronic address: wheeler@bcm.edu, et al. Cell. 2017 Jun 15;169(7):1327-1341.e23. doi: 10.1016/j.cell.2017.05.046. Cell. 2017. PMID: 28622513 Free PMC article.

7

Enhanced inflammation and attenuated tumor suppressor pathways are associated with oncogene-induced lung tumors in aged mice.

Parikh N, Shuck RL, Gagea M, Shen L, Donehower LA. Parikh N, et al. Among authors: donehower la. Aging Cell. 2018 Feb;17(1):e12691. doi: 10.1111/acel.12691. Epub 2017 Oct 18. Aging Cell. 2018. PMID: 29047229 Free PMC article.

8

Absence of p53 in a mouse mammary tumor model promotes tumor cell proliferation without affecting apoptosis.

Jones JM, Attardi L, Godley LA, Laucirica R, Medina D, Jacks T, Varmus HE, Donehower LA. Jones JM, et al. Among authors: donehower la. Cell Growth Differ. 1997 Aug;8(8):829-38. Cell Growth Differ. 1997. PMID: 9269892

9

Genetic background alters the spectrum of tumors that develop in p53-deficient mice.

Harvey M, McArthur MJ, Montgomery CA Jr, Bradley A, Donehower LA. Harvey M, et al. Among authors: donehower la. FASEB J. 1993 Jul;7(10):938-43. doi: 10.1096/fasebj.7.10.8344491. FASEB J. 1993. PMID: 8344491

10

How does suppression of IGF-1 signaling by DNA damage affect aging and longevity?

Hinkal G, Donehower LA. Hinkal G, et al. Among authors: donehower la. Mech Ageing Dev. 2008 May;129(5):243-53. doi: 10.1016/j.mad.2008.02.005. Epub 2008 Feb 17. Mech Ageing Dev. 2008. PMID: 18374391 Free PMC article. Review.

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