Lu H - Search Results

1

Novel recombinant engineered gp41 N-terminal heptad repeat trimers and their potential as anti-HIV-1 therapeutics or microbicides.

Chen X, Lu L, Qi Z, Lu H, Wang J, Yu X, Chen Y, Jiang S. Chen X, et al. Among authors: lu h, lu l. J Biol Chem. 2010 Aug 13;285(33):25506-15. doi: 10.1074/jbc.M110.101170. Epub 2010 Jun 10. J Biol Chem. 2010. PMID: 20538590 Free PMC article.

2

Design of a protein surface antagonist based on alpha-helix mimicry: inhibition of gp41 assembly and viral fusion.

Ernst JT, Kutzki O, Debnath AK, Jiang S, Lu H, Hamilton AD. Ernst JT, et al. Among authors: lu h. Angew Chem Int Ed Engl. 2002 Jan 18;41(2):278-81. doi: 10.1002/1521-3773(20020118)41:2<278::aid-anie278>3.0.co;2-a. Angew Chem Int Ed Engl. 2002. PMID: 12491408 No abstract available.

3

Automatic quantitation of HIV-1 mediated cell-to-cell fusion with a digital image analysis system (DIAS): application for rapid screening of HIV-1 fusion inhibitors.

Lu H, Zhao Q, Xu Z, Jiang S. Lu H, et al. J Virol Methods. 2003 Feb;107(2):155-61. doi: 10.1016/s0166-0934(02)00213-6. J Virol Methods. 2003. PMID: 12505629

4

Development of a cell-based enzyme-linked immunosorbent assay for high-throughput screening of HIV type 1 entry inhibitors targeting the coreceptor CXCR4.

Zhao Q, Lu H, Schols D, De Clercq E, Jiang S. Zhao Q, et al. Among authors: lu h. AIDS Res Hum Retroviruses. 2003 Nov;19(11):947-55. doi: 10.1089/088922203322588297. AIDS Res Hum Retroviruses. 2003. PMID: 14678601

5

Rapid and automated fluorescence-linked immunosorbent assay for high-throughput screening of HIV-1 fusion inhibitors targeting gp41.

Liu S, Boyer-Chatenet L, Lu H, Jiang S. Liu S, et al. Among authors: lu h. J Biomol Screen. 2003 Dec;8(6):685-93. doi: 10.1177/1087057103259155. J Biomol Screen. 2003. PMID: 14711394

6

Synthesis and anti-HIV-1 activity of 4-[4-(4,6-bisphenylamino-triazin-2-ylamino)-5-methoxy-2-methylphenylazo]-5-hydroxynaphthalene-2,7-disulfonic acid and its derivatives.

Naicker KP, Jiang S, Lu H, Ni J, Boyer-Chatenet L, Wang LX, Debnath AK. Naicker KP, et al. Among authors: lu h. Bioorg Med Chem. 2004 Mar 1;12(5):1215-20. doi: 10.1016/j.bmc.2003.11.006. Bioorg Med Chem. 2004. PMID: 14980633

7

N-substituted pyrrole derivatives as novel human immunodeficiency virus type 1 entry inhibitors that interfere with the gp41 six-helix bundle formation and block virus fusion.

Jiang S, Lu H, Liu S, Zhao Q, He Y, Debnath AK. Jiang S, et al. Among authors: lu h. Antimicrob Agents Chemother. 2004 Nov;48(11):4349-59. doi: 10.1128/AAC.48.11.4349-4359.2004. Antimicrob Agents Chemother. 2004. PMID: 15504864 Free PMC article.

8

Different from the HIV fusion inhibitor C34, the anti-HIV drug Fuzeon (T-20) inhibits HIV-1 entry by targeting multiple sites in gp41 and gp120.

Liu S, Lu H, Niu J, Xu Y, Wu S, Jiang S. Liu S, et al. Among authors: lu h. J Biol Chem. 2005 Mar 25;280(12):11259-73. doi: 10.1074/jbc.M411141200. Epub 2005 Jan 7. J Biol Chem. 2005. PMID: 15640162 Free article.

9

Receptor-binding domain of severe acute respiratory syndrome coronavirus spike protein contains multiple conformation-dependent epitopes that induce highly potent neutralizing antibodies.

He Y, Lu H, Siddiqui P, Zhou Y, Jiang S. He Y, et al. Among authors: lu h. J Immunol. 2005 Apr 15;174(8):4908-15. doi: 10.4049/jimmunol.174.8.4908. J Immunol. 2005. PMID: 15814718

10

Theaflavin derivatives in black tea and catechin derivatives in green tea inhibit HIV-1 entry by targeting gp41.

Liu S, Lu H, Zhao Q, He Y, Niu J, Debnath AK, Wu S, Jiang S. Liu S, et al. Among authors: lu h. Biochim Biophys Acta. 2005 May 25;1723(1-3):270-81. doi: 10.1016/j.bbagen.2005.02.012. Epub 2005 Mar 24. Biochim Biophys Acta. 2005. PMID: 15823507

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