Johnson ME - Search Results

1

Severe acute respiratory syndrome coronavirus papain-like novel protease inhibitors: design, synthesis, protein-ligand X-ray structure and biological evaluation.

Ghosh AK, Takayama J, Rao KV, Ratia K, Chaudhuri R, Mulhearn DC, Lee H, Nichols DB, Baliji S, Baker SC, Johnson ME, Mesecar AD. Ghosh AK, et al. Among authors: johnson me. J Med Chem. 2010 Jul 8;53(13):4968-79. doi: 10.1021/jm1004489. J Med Chem. 2010. PMID: 20527968 Free PMC article.

2

Examination of HIV-1 protease secondary structure specificity using conformationally constrained inhibitors.

Kahn M, Nakanishi H, Chrusciel RA, Fitzpatrick D, Johnson ME. Kahn M, et al. Among authors: johnson me. J Med Chem. 1991 Dec;34(12):3395-9. doi: 10.1021/jm00116a009. J Med Chem. 1991. PMID: 1766005 No abstract available.

3

Hemoglobin S antigelation agents based on 5-bromotryptophan with potential for sickle cell anemia.

De Croos PZ, Sangdee P, Stockwell BL, Kar L, Thompson EB, Johnson ME, Currie BL. De Croos PZ, et al. Among authors: johnson me. J Med Chem. 1990 Dec;33(12):3138-42. doi: 10.1021/jm00174a008. J Med Chem. 1990. PMID: 2258900

4

Structure-based design and synthesis of novel thrombin inhibitors based on phosphinic peptide mimetics.

Li M, Lin Z, Johnson ME. Li M, et al. Among authors: johnson me. Bioorg Med Chem Lett. 1999 Jul 19;9(14):1957-62. doi: 10.1016/s0960-894x(99)00319-4. Bioorg Med Chem Lett. 1999. PMID: 10450962

5

An oxyanion-hole selective serine protease inhibitor in complex with trypsin.

Cui J, Marankan F, Fu W, Crich D, Mesecar A, Johnson ME. Cui J, et al. Among authors: johnson me. Bioorg Med Chem. 2002 Jan;10(1):41-6. doi: 10.1016/s0968-0896(01)00259-0. Bioorg Med Chem. 2002. PMID: 11738605

6

Regioselective covalent modification of hemoglobin in search of antisickling agents.

Park S, Hayes BL, Marankan F, Mulhearn DC, Wanna L, Mesecar AD, Santarsiero BD, Johnson ME, Venton DL. Park S, et al. Among authors: johnson me. J Med Chem. 2003 Mar 13;46(6):936-53. doi: 10.1021/jm020361k. J Med Chem. 2003. PMID: 12620071

7

Design, synthesis, and evaluation of oxyanion-hole selective inhibitor substituents for the S1 subsite of factor Xa.

Rumthao S, Lee O, Sheng Q, Fu W, Mulhearn DC, Crich D, Mesecar AD, Johnson ME. Rumthao S, et al. Among authors: johnson me. Bioorg Med Chem Lett. 2004 Oct 18;14(20):5165-70. doi: 10.1016/j.bmcl.2004.07.054. Bioorg Med Chem Lett. 2004. PMID: 15380220

8

Design and synthesis of peptidomimetic severe acute respiratory syndrome chymotrypsin-like protease inhibitors.

Ghosh AK, Xi K, Ratia K, Santarsiero BD, Fu W, Harcourt BH, Rota PA, Baker SC, Johnson ME, Mesecar AD. Ghosh AK, et al. Among authors: johnson me. J Med Chem. 2005 Nov 3;48(22):6767-71. doi: 10.1021/jm050548m. J Med Chem. 2005. PMID: 16250632

9

Structural and functional analysis of two glutamate racemase isozymes from Bacillus anthracis and implications for inhibitor design.

May M, Mehboob S, Mulhearn DC, Wang Z, Yu H, Thatcher GR, Santarsiero BD, Johnson ME, Mesecar AD. May M, et al. Among authors: johnson me. J Mol Biol. 2007 Aug 31;371(5):1219-37. doi: 10.1016/j.jmb.2007.05.093. Epub 2007 Jun 4. J Mol Biol. 2007. PMID: 17610893 Free PMC article.

10

Structure-based design, synthesis, and biological evaluation of peptidomimetic SARS-CoV 3CLpro inhibitors.

Ghosh AK, Xi K, Grum-Tokars V, Xu X, Ratia K, Fu W, Houser KV, Baker SC, Johnson ME, Mesecar AD. Ghosh AK, et al. Among authors: johnson me. Bioorg Med Chem Lett. 2007 Nov 1;17(21):5876-80. doi: 10.1016/j.bmcl.2007.08.031. Epub 2007 Aug 19. Bioorg Med Chem Lett. 2007. PMID: 17855091 Free PMC article.

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