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Insertion of epicatechin gallate into the cytoplasmic membrane of methicillin-resistant Staphylococcus aureus disrupts penicillin-binding protein (PBP) 2a-mediated beta-lactam resistance by delocalizing PBP2.
Bernal P, Lemaire S, Pinho MG, Mobashery S, Hinds J, Taylor PW. Bernal P, et al. Among authors: lemaire s. J Biol Chem. 2010 Jul 30;285(31):24055-65. doi: 10.1074/jbc.M110.114793. Epub 2010 Jun 1. J Biol Chem. 2010. PMID: 20516078 Free PMC article.
Restoration of susceptibility of intracellular methicillin-resistant Staphylococcus aureus to beta-lactams: comparison of strains, cells, and antibiotics.
Lemaire S, Olivier A, Van Bambeke F, Tulkens PM, Appelbaum PC, Glupczynski Y. Lemaire S, et al. Antimicrob Agents Chemother. 2008 Aug;52(8):2797-805. doi: 10.1128/AAC.00123-08. Epub 2008 Jun 2. Antimicrob Agents Chemother. 2008. PMID: 18519727 Free PMC article.
Staphylococcus aureus invades eukaryotic cells. When methicillin-resistant S. aureus (MRSA) ATCC 33591 is phagocytized by human THP-1 macrophages, complete restoration of susceptibility to cloxacillin and meropenem is shown and the strain becomes indistinguishable from MSS …
Staphylococcus aureus invades eukaryotic cells. When methicillin-resistant S. aureus (MRSA) ATCC 33591 is phagocytized by human THP-1 …
Intracellular forms of menadione-dependent small-colony variants of methicillin-resistant Staphylococcus aureus are hypersusceptible to β-lactams in a THP-1 cell model due to cooperation between vacuolar acidic pH and oxidant species.
Garcia LG, Lemaire S, Kahl BC, Becker K, Proctor RA, Tulkens PM, Van Bambeke F. Garcia LG, et al. Among authors: lemaire s. J Antimicrob Chemother. 2012 Dec;67(12):2873-81. doi: 10.1093/jac/dks325. Epub 2012 Sep 21. J Antimicrob Chemother. 2012. PMID: 23002174
Activities of ceftobiprole and other cephalosporins against extracellular and intracellular (THP-1 macrophages and keratinocytes) forms of methicillin-susceptible and methicillin-resistant Staphylococcus aureus.
Lemaire S, Glupczynski Y, Duval V, Joris B, Tulkens PM, Van Bambeke F. Lemaire S, et al. Antimicrob Agents Chemother. 2009 Jun;53(6):2289-97. doi: 10.1128/AAC.01135-08. Epub 2009 Mar 16. Antimicrob Agents Chemother. 2009. PMID: 19289525 Free PMC article.
Cellular pharmacokinetics and intracellular activity against Listeria monocytogenes and Staphylococcus aureus of chemically modified and nanoencapsulated gentamicin.
Imbuluzqueta E, Lemaire S, Gamazo C, Elizondo E, Ventosa N, Veciana J, Van Bambeke F, Blanco-Prieto MJ. Imbuluzqueta E, et al. Among authors: lemaire s. J Antimicrob Chemother. 2012 Sep;67(9):2158-64. doi: 10.1093/jac/dks172. Epub 2012 May 21. J Antimicrob Chemother. 2012. PMID: 22615297 Free article.
Pharmacodynamic evaluation of the activity of antibiotics against hemin- and menadione-dependent small-colony variants of Staphylococcus aureus in models of extracellular (broth) and intracellular (THP-1 monocytes) infections.
Garcia LG, Lemaire S, Kahl BC, Becker K, Proctor RA, Denis O, Tulkens PM, Van Bambeke F. Garcia LG, et al. Among authors: lemaire s. Antimicrob Agents Chemother. 2012 Jul;56(7):3700-11. doi: 10.1128/AAC.00285-12. Epub 2012 May 7. Antimicrob Agents Chemother. 2012. PMID: 22564838 Free PMC article.
679 results