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Insulin-like growth factor-binding protein-3 promotes transforming growth factor-{beta}1-mediated epithelial-to-mesenchymal transition and motility in transformed human esophageal cells.
Natsuizaka M, Ohashi S, Wong GS, Ahmadi A, Kalman RA, Budo D, Klein-Szanto AJ, Herlyn M, Diehl JA, Nakagawa H. Natsuizaka M, et al. Carcinogenesis. 2010 Aug;31(8):1344-53. doi: 10.1093/carcin/bgq108. Epub 2010 May 31. Carcinogenesis. 2010. PMID: 20513670 Free PMC article.
Fibroblast growth factor-2-mediated FGFR/Erk signaling supports maintenance of cancer stem-like cells in esophageal squamous cell carcinoma.
Maehara O, Suda G, Natsuizaka M, Ohnishi S, Komatsu Y, Sato F, Nakai M, Sho T, Morikawa K, Ogawa K, Shimazaki T, Kimura M, Asano A, Fujimoto Y, Ohashi S, Kagawa S, Kinugasa H, Naganuma S, Whelan KA, Nakagawa H, Nakagawa K, Takeda H, Sakamoto N. Maehara O, et al. Among authors: natsuizaka m. Carcinogenesis. 2017 Oct 26;38(11):1073-1083. doi: 10.1093/carcin/bgx095. Carcinogenesis. 2017. PMID: 28927233 Free PMC article.
Hypoxia activates the cyclooxygenase-2-prostaglandin E synthase axis.
Lee JJ, Natsuizaka M, Ohashi S, Wong GS, Takaoka M, Michaylira CZ, Budo D, Tobias JW, Kanai M, Shirakawa Y, Naomoto Y, Klein-Szanto AJ, Haase VH, Nakagawa H. Lee JJ, et al. Among authors: natsuizaka m. Carcinogenesis. 2010 Mar;31(3):427-34. doi: 10.1093/carcin/bgp326. Epub 2009 Dec 30. Carcinogenesis. 2010. PMID: 20042640 Free PMC article.
Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors.
Ohashi S, Natsuizaka M, Wong GS, Michaylira CZ, Grugan KD, Stairs DB, Kalabis J, Vega ME, Kalman RA, Nakagawa M, Klein-Szanto AJ, Herlyn M, Diehl JA, Rustgi AK, Nakagawa H. Ohashi S, et al. Among authors: natsuizaka m. Cancer Res. 2010 May 15;70(10):4174-84. doi: 10.1158/0008-5472.CAN-09-4614. Epub 2010 Apr 27. Cancer Res. 2010. PMID: 20424117 Free PMC article.
A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors.
Ohashi S, Natsuizaka M, Naganuma S, Kagawa S, Kimura S, Itoh H, Kalman RA, Nakagawa M, Darling DS, Basu D, Gimotty PA, Klein-Szanto AJ, Diehl JA, Herlyn M, Nakagawa H. Ohashi S, et al. Among authors: natsuizaka m. Cancer Res. 2011 Nov 1;71(21):6836-47. doi: 10.1158/0008-5472.CAN-11-0846. Epub 2011 Sep 2. Cancer Res. 2011. PMID: 21890822 Free PMC article.
Cellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor-suppressor activities.
Kagawa S, Natsuizaka M, Whelan KA, Facompre N, Naganuma S, Ohashi S, Kinugasa H, Egloff AM, Basu D, Gimotty PA, Klein-Szanto AJ, Bass AJ, Wong KK, Diehl JA, Rustgi AK, Nakagawa H. Kagawa S, et al. Among authors: natsuizaka m. Oncogene. 2015 Apr 30;34(18):2347-59. doi: 10.1038/onc.2014.169. Epub 2014 Jun 16. Oncogene. 2015. PMID: 24931169 Free PMC article.
Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance.
Whelan KA, Chandramouleeswaran PM, Tanaka K, Natsuizaka M, Guha M, Srinivasan S, Darling DS, Kita Y, Natsugoe S, Winkler JD, Klein-Szanto AJ, Amaravadi RK, Avadhani NG, Rustgi AK, Nakagawa H. Whelan KA, et al. Among authors: natsuizaka m. Oncogene. 2017 Aug 24;36(34):4843-4858. doi: 10.1038/onc.2017.102. Epub 2017 Apr 17. Oncogene. 2017. PMID: 28414310 Free PMC article.
96 results