Cuny GD - Search Results

1

Identification of translational activators of glial glutamate transporter EAAT2 through cell-based high-throughput screening: an approach to prevent excitotoxicity.

Colton CK, Kong Q, Lai L, Zhu MX, Seyb KI, Cuny GD, Xian J, Glicksman MA, Lin CL. Colton CK, et al. Among authors: cuny gd. J Biomol Screen. 2010 Jul;15(6):653-62. doi: 10.1177/1087057110370998. Epub 2010 May 27. J Biomol Screen. 2010. PMID: 20508255 Free PMC article.

2

Glutamate transporter EAAT2: a new target for the treatment of neurodegenerative diseases.

Lin CL, Kong Q, Cuny GD, Glicksman MA. Lin CL, et al. Among authors: cuny gd. Future Med Chem. 2012 Sep;4(13):1689-700. doi: 10.4155/fmc.12.122. Future Med Chem. 2012. PMID: 22924507 Free PMC article.

3

Restored glial glutamate transporter EAAT2 function as a potential therapeutic approach for Alzheimer's disease.

Takahashi K, Kong Q, Lin Y, Stouffer N, Schulte DA, Lai L, Liu Q, Chang LC, Dominguez S, Xing X, Cuny GD, Hodgetts KJ, Glicksman MA, Lin CL. Takahashi K, et al. Among authors: cuny gd. J Exp Med. 2015 Mar 9;212(3):319-32. doi: 10.1084/jem.20140413. Epub 2015 Feb 23. J Exp Med. 2015. PMID: 25711212 Free PMC article.

4

Identification of small molecule inhibitors of the mitotic kinase haspin by high-throughput screening using a homogeneous time-resolved fluorescence resonance energy transfer assay.

Patnaik D, Jun Xian, Glicksman MA, Cuny GD, Stein RL, Higgins JM. Patnaik D, et al. Among authors: cuny gd. J Biomol Screen. 2008 Dec;13(10):1025-34. doi: 10.1177/1087057108326081. Epub 2008 Oct 31. J Biomol Screen. 2008. PMID: 18978305 Free PMC article.

5

Kinetic-based high-throughput screening assay to discover novel classes of macrophage migration inhibitory factor inhibitors.

Ouertatani-Sakouhi H, Liu M, El-Turk F, Cuny GD, Glicksman MA, Lashuel HA. Ouertatani-Sakouhi H, et al. Among authors: cuny gd. J Biomol Screen. 2010 Apr;15(4):347-58. doi: 10.1177/1087057110363825. Epub 2010 Mar 15. J Biomol Screen. 2010. PMID: 20231420

6

Structure-activity relationship study of pyridazine derivatives as glutamate transporter EAAT2 activators.

Xing X, Chang LC, Kong Q, Colton CK, Lai L, Glicksman MA, Lin CL, Cuny GD. Xing X, et al. Among authors: cuny gd. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5774-7. doi: 10.1016/j.bmcl.2011.08.009. Epub 2011 Aug 8. Bioorg Med Chem Lett. 2011. PMID: 21875806 Free PMC article.

7

Identification of novel compounds that increase SMN protein levels using an improved SMN2 reporter cell assay.

Cherry JJ, Evans MC, Ni J, Cuny GD, Glicksman MA, Androphy EJ. Cherry JJ, et al. Among authors: cuny gd. J Biomol Screen. 2012 Apr;17(4):481-95. doi: 10.1177/1087057111431605. Epub 2012 Jan 10. J Biomol Screen. 2012. PMID: 22233647 Free PMC article.

8

Small-molecule activator of glutamate transporter EAAT2 translation provides neuroprotection.

Kong Q, Chang LC, Takahashi K, Liu Q, Schulte DA, Lai L, Ibabao B, Lin Y, Stouffer N, Das Mukhopadhyay C, Xing X, Seyb KI, Cuny GD, Glicksman MA, Lin CL. Kong Q, et al. Among authors: cuny gd. J Clin Invest. 2014 Mar;124(3):1255-67. doi: 10.1172/JCI66163. Epub 2014 Feb 24. J Clin Invest. 2014. PMID: 24569372 Free PMC article.

9

Enzymatic Characterization of ER Stress-Dependent Kinase, PERK, and Development of a High-Throughput Assay for Identification of PERK Inhibitors.

Pytel D, Seyb K, Liu M, Ray SS, Concannon J, Huang M, Cuny GD, Diehl JA, Glicksman MA. Pytel D, et al. Among authors: cuny gd. J Biomol Screen. 2014 Aug;19(7):1024-34. doi: 10.1177/1087057114525853. Epub 2014 Mar 5. J Biomol Screen. 2014. PMID: 24598103 Free PMC article.

10

Small-molecule inhibitors of phosphatidylcholine transfer protein/StarD2 identified by high-throughput screening.

Wagle N, Xian J, Shishova EY, Wei J, Glicksman MA, Cuny GD, Stein RL, Cohen DE. Wagle N, et al. Among authors: cuny gd. Anal Biochem. 2008 Dec 1;383(1):85-92. doi: 10.1016/j.ab.2008.07.039. Epub 2008 Aug 12. Anal Biochem. 2008. PMID: 18762160 Free PMC article.

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