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mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs.
Dowling RJ, Topisirovic I, Alain T, Bidinosti M, Fonseca BD, Petroulakis E, Wang X, Larsson O, Selvaraj A, Liu Y, Kozma SC, Thomas G, Sonenberg N. Dowling RJ, et al. Among authors: topisirovic i. Science. 2010 May 28;328(5982):1172-6. doi: 10.1126/science.1187532. Science. 2010. PMID: 20508131 Free PMC article.
p53-dependent translational control of senescence and transformation via 4E-BPs.
Petroulakis E, Parsyan A, Dowling RJ, LeBacquer O, Martineau Y, Bidinosti M, Larsson O, Alain T, Rong L, Mamane Y, Paquet M, Furic L, Topisirovic I, Shahbazian D, Livingstone M, Costa-Mattioli M, Teodoro JG, Sonenberg N. Petroulakis E, et al. Among authors: topisirovic i. Cancer Cell. 2009 Nov 6;16(5):439-46. doi: 10.1016/j.ccr.2009.09.025. Cancer Cell. 2009. PMID: 19878875 Free article.
Dissecting the role of mTOR: lessons from mTOR inhibitors.
Dowling RJ, Topisirovic I, Fonseca BD, Sonenberg N. Dowling RJ, et al. Among authors: topisirovic i. Biochim Biophys Acta. 2010 Mar;1804(3):433-9. doi: 10.1016/j.bbapap.2009.12.001. Epub 2009 Dec 11. Biochim Biophys Acta. 2010. PMID: 20005306 Review.
Cell biology. Burn out or fade away?
Topisirovic I, Sonenberg N. Topisirovic I, et al. Science. 2010 Mar 5;327(5970):1210-1. doi: 10.1126/science.1187497. Science. 2010. PMID: 20203039 No abstract available.
S6K1 plays a critical role in early adipocyte differentiation.
Carnevalli LS, Masuda K, Frigerio F, Le Bacquer O, Um SH, Gandin V, Topisirovic I, Sonenberg N, Thomas G, Kozma SC. Carnevalli LS, et al. Among authors: topisirovic i. Dev Cell. 2010 May 18;18(5):763-74. doi: 10.1016/j.devcel.2010.02.018. Dev Cell. 2010. PMID: 20493810 Free PMC article.
4E-BPs at the crossroads of oncogenic MAPK and AKT signaling.
Topisirovic I, Sonenberg N. Topisirovic I, et al. Pigment Cell Melanoma Res. 2010 Oct;23(5):585-6. doi: 10.1111/j.1755-148X.2010.00749.x. Epub 2010 Aug 5. Pigment Cell Melanoma Res. 2010. PMID: 20704686 No abstract available.
136 results