Boger DL - Search Results

1

Identification of broad-based HIV-1 protease inhibitors from combinatorial libraries.

Chang MW, Giffin MJ, Muller R, Savage J, Lin YC, Hong S, Jin W, Whitby LR, Elder JH, Boger DL, Torbett BE. Chang MW, et al. Among authors: boger dl. Biochem J. 2010 Aug 1;429(3):527-32. doi: 10.1042/BJ20091645. Biochem J. 2010. PMID: 20507280 Free PMC article.

2

Two comparisons of the performance of positional scanning and deletion synthesis for the identification of active constituents in mixture combinatorial libraries.

Boger DL, Lee JK, Goldberg J, Jin Q. Boger DL, et al. J Org Chem. 2000 Mar 10;65(5):1467-74. doi: 10.1021/jo9916481. J Org Chem. 2000. PMID: 10814111

3

Development of a solution-phase synthesis of minor groove binding bis-intercalators based on triostin A suitable for combinatorial synthesis.

Boger DL, Lee JK. Boger DL, et al. J Org Chem. 2000 Sep 22;65(19):5996-6000. doi: 10.1021/jo000382r. J Org Chem. 2000. PMID: 10987932

4

Identification of a novel class of small-molecule antiangiogenic agents through the screening of combinatorial libraries which function by inhibiting the binding and localization of proteinase MMP2 to integrin alpha(V)beta(3).

Boger DL, Goldberg J, Silletti S, Kessler T, Cheresh DA. Boger DL, et al. J Am Chem Soc. 2001 Feb 21;123(7):1280-8. doi: 10.1021/ja003579+. J Am Chem Soc. 2001. PMID: 11456699

5

Erythropoietin mimetics derived from solution phase combinatorial libraries.

Goldberg J, Jin Q, Ambroise Y, Satoh S, Desharnais J, Capps K, Boger DL. Goldberg J, et al. Among authors: boger dl. J Am Chem Soc. 2002 Jan 30;124(4):544-55. doi: 10.1021/ja0118789. J Am Chem Soc. 2002. PMID: 11804483

6

Solution-phase synthesis of combinatorial libraries designed to modulate protein-protein or protein-DNA interactions.

Boger DL. Boger DL. Bioorg Med Chem. 2003 Apr 17;11(8):1607-13. doi: 10.1016/s0968-0896(03)00031-2. Bioorg Med Chem. 2003. PMID: 12659745 Review.

7

Solution-phase combinatorial libraries: modulating cellular signaling by targeting protein-protein or protein-DNA interactions.

Boger DL, Desharnais J, Capps K. Boger DL, et al. Angew Chem Int Ed Engl. 2003 Sep 15;42(35):4138-76. doi: 10.1002/anie.200300574. Angew Chem Int Ed Engl. 2003. PMID: 14502729 Review.

8

An in vitro and in vivo disconnect uncovered through high-throughput identification of botulinum neurotoxin A antagonists.

Eubanks LM, Hixon MS, Jin W, Hong S, Clancy CM, Tepp WH, Baldwin MR, Malizio CJ, Goodnough MC, Barbieri JT, Johnson EA, Boger DL, Dickerson TJ, Janda KD. Eubanks LM, et al. Among authors: boger dl. Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2602-7. doi: 10.1073/pnas.0611213104. Epub 2007 Feb 9. Proc Natl Acad Sci U S A. 2007. PMID: 17293454 Free PMC article.

9

A unique class of duocarmycin and CC-1065 analogues subject to reductive activation.

Jin W, Trzupek JD, Rayl TJ, Broward MA, Vielhauer GA, Weir SJ, Hwang I, Boger DL. Jin W, et al. Among authors: boger dl. J Am Chem Soc. 2007 Dec 12;129(49):15391-7. doi: 10.1021/ja075398e. Epub 2007 Nov 17. J Am Chem Soc. 2007. PMID: 18020335 Free PMC article.

10

Unique small molecule entry inhibitors of hemorrhagic fever arenaviruses.

Lee AM, Rojek JM, Spiropoulou CF, Gundersen AT, Jin W, Shaginian A, York J, Nunberg JH, Boger DL, Oldstone MB, Kunz S. Lee AM, et al. Among authors: boger dl. J Biol Chem. 2008 Jul 4;283(27):18734-42. doi: 10.1074/jbc.M802089200. Epub 2008 May 12. J Biol Chem. 2008. PMID: 18474596 Free PMC article.

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