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Nicotine inhibits Fc epsilon RI-induced cysteinyl leukotrienes and cytokine production without affecting mast cell degranulation through alpha 7/alpha 9/alpha 10-nicotinic receptors.
Mishra NC, Rir-sima-ah J, Boyd RT, Singh SP, Gundavarapu S, Langley RJ, Razani-Boroujerdi S, Sopori ML. Mishra NC, et al. Among authors: singh sp. J Immunol. 2010 Jul 1;185(1):588-96. doi: 10.4049/jimmunol.0902227. Epub 2010 May 26. J Immunol. 2010. PMID: 20505147 Free PMC article.
Chronic nicotine inhibits inflammation and promotes influenza infection.
Razani-Boroujerdi S, Singh SP, Knall C, Hahn FF, Peña-Philippides JC, Kalra R, Langley RJ, Sopori ML. Razani-Boroujerdi S, et al. Among authors: singh sp. Cell Immunol. 2004 Jul;230(1):1-9. doi: 10.1016/j.cellimm.2004.07.007. Cell Immunol. 2004. PMID: 15541713
T cells express alpha7-nicotinic acetylcholine receptor subunits that require a functional TCR and leukocyte-specific protein tyrosine kinase for nicotine-induced Ca2+ response.
Razani-Boroujerdi S, Boyd RT, Dávila-García MI, Nandi JS, Mishra NC, Singh SP, Pena-Philippides JC, Langley R, Sopori ML. Razani-Boroujerdi S, et al. Among authors: singh sp. J Immunol. 2007 Sep 1;179(5):2889-98. doi: 10.4049/jimmunol.179.5.2889. J Immunol. 2007. PMID: 17709503
Maternal exposure to secondhand cigarette smoke primes the lung for induction of phosphodiesterase-4D5 isozyme and exacerbated Th2 responses: rolipram attenuates the airway hyperreactivity and muscarinic receptor expression but not lung inflammation and atopy.
Singh SP, Mishra NC, Rir-Sima-Ah J, Campen M, Kurup V, Razani-Boroujerdi S, Sopori ML. Singh SP, et al. J Immunol. 2009 Aug 1;183(3):2115-21. doi: 10.4049/jimmunol.0900826. Epub 2009 Jul 13. J Immunol. 2009. PMID: 19596983 Free PMC article.
The role of IL-1β in nicotine-induced immunosuppression and neuroimmune communication.
Razani-Boroujerdi S, Langley RJ, Singh SP, Pena-Philippides JC, Rir-sima-ah J, Gundavarapu S, Mishra NC, Sopori ML. Razani-Boroujerdi S, et al. Among authors: singh sp. J Neuroimmune Pharmacol. 2011 Dec;6(4):585-96. doi: 10.1007/s11481-011-9284-5. Epub 2011 Jun 14. J Neuroimmune Pharmacol. 2011. PMID: 21671006 Free PMC article.
Role of nicotinic receptors and acetylcholine in mucous cell metaplasia, hyperplasia, and airway mucus formation in vitro and in vivo.
Gundavarapu S, Wilder JA, Mishra NC, Rir-Sima-Ah J, Langley RJ, Singh SP, Saeed AI, Jaramillo RJ, Gott KM, Peña-Philippides JC, Harrod KS, McIntosh JM, Buch S, Sopori ML. Gundavarapu S, et al. Among authors: singh sp. J Allergy Clin Immunol. 2012 Sep;130(3):770-780.e11. doi: 10.1016/j.jaci.2012.04.002. Epub 2012 May 9. J Allergy Clin Immunol. 2012. PMID: 22578901 Free PMC article.
Gestational Exposure to Sidestream (Secondhand) Cigarette Smoke Promotes Transgenerational Epigenetic Transmission of Exacerbated Allergic Asthma and Bronchopulmonary Dysplasia.
Singh SP, Chand HS, Langley RJ, Mishra N, Barrett T, Rudolph K, Tellez C, Filipczak PT, Belinsky S, Saeed AI, Sheybani A, Exil V, Agarwal H, Sidhaye VK, Sussan T, Biswal S, Sopori M. Singh SP, et al. J Immunol. 2017 May 15;198(10):3815-3822. doi: 10.4049/jimmunol.1700014. Epub 2017 Apr 5. J Immunol. 2017. PMID: 28381639 Free PMC article.
2,833 results